Alastair Droop
Alastair Droop
Wellcome Sanger Institute
Verified email at sanger.ac.uk - Homepage
TitleCited byYear
Gene expression profiling of human prostate cancer stem cells reveals a pro-inflammatory phenotype and the importance of extracellular matrix interactions
R Birnie, SD Bryce, C Roome, V Dussupt, A Droop, SH Lang, PA Berry, ...
Genome biology 9 (5), R83, 2008
2012008
Genomic Subtypes of Non-invasive Bladder Cancer with Distinct Metabolic Profile and Female Gender Bias in KDM6A Mutation Frequency
CD Hurst, O Alder, FM Platt, A Droop, LF Stead, JE Burns, GJ Burghel, ...
Cancer Cell 32 (5), 701-715. e7, 2017
482017
Prediction of clinical outcome in glioblastoma using a biologically relevant nine-microRNA signature
J Hayes, H Thygesen, C Tumilson, A Droop, M Boissinot, TA Hughes, ...
Molecular oncology 9 (3), 704-714, 2015
422015
Loss of CSL unlocks a hypoxic response and enhanced tumor growth potential in breast cancer cells
EB Braune, YL Tsoi, YP Phoon, S Landor, HS Cascales, D Ramsköld, ...
Stem cell reports 6 (5), 643-651, 2016
29*2016
Retinoic acid and androgen receptors combine to achieve tissue specific control of human prostatic transglutaminase expression: a novel regulatory network with broader significance
GC Rivera-Gonzalez, AP Droop, HJ Rippon, K Tiemann, D Pellacani, ...
Nucleic acids research 40 (11), 4825-4840, 2012
272012
DNA hypermethylation in prostate cancer is a consequence of aberrant epithelial differentiation and hyperproliferation
D Pellacani, D Kestoras, AP Droop, FM Frame, PA Berry, MG Lawrence, ...
Cell death and differentiation 21 (5), 761, 2014
262014
The calcium sensor STIM1 is regulated by androgens in prostate stromal cells
PA Berry, R Birnie, AP Droop, NJ Maitland, AT Collins
The Prostate 71 (15), 1646-1655, 2011
212011
Simulation validation: exploring the suitability of a simulation of cell division and differentiation in the prostate
FAC Polack, A Droop, P Garnett, T Ghetiu, S Stepney
Proceedings of the 2011 Workshop on Complex Systems Modelling and Simulation …, 2011
202011
Elucidating drivers of oral epithelial dysplasia formation and malignant transformation to cancer using RNAseq
C Conway, JL Graham, P Chengot, C Daly, R Chalkley, L Ross, A Droop, ...
Oncotarget 6 (37), 40186, 2015
172015
Multiple model simulation: modelling cell division and differentiation in the prostate
A Droop, P Garnett, FAC Polack, S Stepney
Proceedings of the 2011 Workshop on Complex Systems Modelling and Simulation …, 2011
152011
Engineering Simulations as Scientific Instruments: A Pattern Language: With Kieran Alden, Paul S. Andrews, James L. Bown, Alastair Droop, Richard B. Greaves, Mark Read, Adam T …
S Stepney, FAC Polack
Springer International Publishing, 2018
142018
Prognostic microRNAs in high-grade glioma reveal a link to oligodendrocyte precursor differentiation
J Hayes, H Thygesen, A Droop, TA Hughes, D Westhead, SE Lawler, ...
Oncoscience 2 (3), 252, 2015
122015
Prostate-regenerating capacity of cultured human adult prostate epithelial cells
M Yao, RA Taylor, MG Richards, P Sved, J Wong, D Eisinger, C Xie, ...
Cells Tissues Organs 191 (3), 203-212, 2010
112010
Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa
A Buskin, L Zhu, V Chichagova, B Basu, S Mozaffari-Jovin, D Dolan, ...
Nature communications 9 (1), 4234, 2018
92018
β-Catenin–mediated immune evasion pathway frequently operates in primary cutaneous melanomas
J Nsengimana, J Laye, A Filia, S O’Shea, S Muralidhar, J Poźniak, ...
The Journal of clinical investigation 128 (5), 2048-2063, 2018
92018
A quantitative measure of non-neutral evolutionary activity for systems that exhibit intrinsic fitness
A Droop, S Hickinbotham
Artificial Life Conference Proceedings 12, 45-52, 2012
92012
A case-matched gender comparison transcriptomic screen identifies eIF4E and eIF5 as potential prognostic markers in male breast cancer
MP Humphries, SS Rajan, A Droop, CAB Suleman, C Carbone, C Nilsson, ...
Clinical Cancer Research 23 (10), 2575-2583, 2017
82017
Properties of biological mutation networks and their implications for alife
AP Droop, SJ Hickinbotham
Artificial Life 17 (4), 353-364, 2011
82011
Changes in plasma chemokine CC motif ligand 2 levels during treatment with eicosapentaenoic acid predict outcome in patients undergoing surgery for colorectal cancer liver …
M Volpato, SL Perry, G Marston, N Ingram, AJ Cockbain, H Burghel, ...
Oncotarget 7 (19), 28139, 2016
72016
KHS101 disrupts energy metabolism in human glioblastoma cells and reduces tumor growth in mice
ES Polson, VB Kuchler, C Abbosh, EM Ross, RK Mathew, HA Beard, ...
Science translational medicine 10 (454), eaar2718, 2018
62018
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