Norman JC
Norman JC
Group Leader, Beatson Institute
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TitleCited byYear
Mutant p53 drives invasion by promoting integrin recycling
PAJ Muller, PT Caswell, B Doyle, MP Iwanicki, EH Tan, S Karim, ...
Cell 139 (7), 1327-1341, 2009
Integrins: masters and slaves of endocytic transport
PT Caswell, S Vadrevu, JC Norman
Nature reviews Molecular cell biology 10 (12), 843, 2009
Stimulation of tumor growth and angiogenesis by low concentrations of RGD-mimetic integrin inhibitors
AR Reynolds, IR Hart, AR Watson, JC Welti, RG Silva, SD Robinson, ...
Nature medicine 15 (4), 392, 2009
p53 and its mutants in tumor cell migration and invasion
PAJ Muller, KH Vousden, JC Norman
The Journal of cell biology 192 (2), 209-218, 2011
Rab25 associates with α5β1 integrin to promote invasive migration in 3D microenvironments
PT Caswell, HJ Spence, M Parsons, DP White, K Clark, KW Cheng, ...
Developmental cell 13 (4), 496-510, 2007
Integrin trafficking and the control of cell migration
PT Caswell, JC Norman
Traffic 7 (1), 14-21, 2006
PDGF-regulated rab4-dependent recycling of αvβ3 integrin from early endosomes is necessary for cell adhesion and spreading
M Roberts, S Barry, A Woods, P van der Sluijs, J Norman
Current Biology 11 (18), 1392-1402, 2001
Rab-coupling protein coordinates recycling of α5β1 integrin and EGFR1 to promote cell migration in 3D microenvironments
PT Caswell, M Chan, AJ Lindsay, MW McCaffrey, D Boettiger, JC Norman
J Cell Biol 183 (1), 143-155, 2008
Mechanisms of integrin activation and trafficking
C Margadant, HN Monsuur, JC Norman, A Sonnenberg
Current opinion in cell biology 23 (5), 607-614, 2011
Endocytic recycling pathways: emerging regulators of cell migration
MC Jones, PT Caswell, JC Norman
Current opinion in cell biology 18 (5), 549-557, 2006
Structure and function of the complex formed by the tuberculosis virulence factors CFP‐10 and ESAT‐6
PS Renshaw, KL Lightbody, V Veverka, FW Muskett, G Kelly, TA Frenkiel, ...
The EMBO journal 24 (14), 2491-2498, 2005
RhoB and actin polymerization coordinate Src activation with endosome-mediated delivery to the membrane
E Sandilands, C Cans, VJ Fincham, VG Brunton, H Mellor, ...
Developmental cell 7 (6), 855-869, 2004
αvβ3 and α5β1 integrin recycling pathways dictate downstream Rho kinase signaling to regulate persistent cell migration
DP White, PT Caswell, JC Norman
J Cell Biol 177 (3), 515-525, 2007
Endocytic transport of integrins during cell migration and invasion
P Caswell, J Norman
Trends in cell biology 18 (6), 257-263, 2008
Neuropilin-1/GIPC1 signaling regulates α5β1 integrin traffic and function in endothelial cells
D Valdembri, PT Caswell, KI Anderson, JP Schwarz, I König, E Astanina, ...
PLoS biology 7 (1), e1000025, 2009
Rab25 and CLIC3 collaborate to promote integrin recycling from late endosomes/lysosomes and drive cancer progression
MA Dozynkiewicz, NB Jamieson, I MacPherson, J Grindlay, ...
Developmental cell 22 (1), 131-145, 2012
PKD1/PKCμ promotes αvβ3 integrin recycling and delivery to nascent focal adhesions
AJ Woods, DP White, PT Caswell, JC Norman
The EMBO journal 23 (13), 2531-2543, 2004
Protein kinase B/Akt acts via glycogen synthase kinase 3 to regulate recycling of αvβ3 and α5β1 integrins
MS Roberts, AJ Woods, TC Dale, P van der Sluijs, JC Norman
Molecular and cellular biology 24 (4), 1505-1515, 2004
VEGF regulates the mobilization of VEGFR2/KDR from an intracellular endothelial storage compartment
A Gampel, L Moss, MC Jones, V Brunton, JC Norman, H Mellor
Blood 108 (8), 2624-2631, 2006
ARF1 mediates paxillin recruitment to focal adhesions and potentiates Rho-stimulated stress fiber formation in intact and permeabilized Swiss 3T3 fibroblasts
JC Norman, D Jones, ST Barry, MR Holt, S Cockcroft, DR Critchley
J Cell Biol 143 (7), 1981-1995, 1998
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