| Benzothiazinones kill Mycobacterium tuberculosis by blocking arabinan synthesis V Makarov, G Manina, K Mikusova, U Möllmann, O Ryabova, ... Science 324 (5928), 801-804, 2009 | 839 | 2009 |
| Structural Basis for Benzothiazinone-Mediated Killing of Mycobacterium tuberculosis J Neres, F Pojer, E Molteni, LR Chiarelli, N Dhar, S Boy-Röttger, S Buroni, ... Science Translational Medicine 4 (150), 150ra121-150ra121, 2012 | 206 | 2012 |
| Arylamine N-acetyltransferases: structural and functional implications of polymorphisms E Sim, N Lack, CJ Wang, H Long, I Westwood, E Fullam, A Kawamura Toxicology 254 (3), 170-183, 2008 | 155 | 2008 |
| Arylamine N-acetyltransferases E Sim, I Westwood, E Fullam Informa UK Ltd 3 (2), 169-184, 2007 | 89 | 2007 |
| Evaluation of the Antimicrobial Activity of Cationic Polymers Against Mycobacteria: Towards Anti-Tubercular Macromolecules DJ Phillips, J Harrison, SJ Richards, DE Mitchell, E Tichauer, ... Biomacromolecules, 2017 | 80 | 2017 |
| Binding of the anti‐tubercular drug isoniazid to the arylamine N‐acetyltransferase protein from Mycobacterium smegmatis J Sandy, S Holton, E Fullam, E Sim, M Noble Protein science 14 (3), 775-782, 2005 | 78 | 2005 |
| Structure and mechanism of arylamine N-acetyltransferases IM Westwood, A Kawamura, E Fullam, AJ Russell, SG Davies, E Sim Current topics in medicinal chemistry 6 (15), 1641-1654, 2006 | 65 | 2006 |
| Identification of arylamine N-acetyltransferase inhibitors as an approach towards novel anti-tuberculars IM Westwood, S Bhakta, AJ Russell, E Fullam, MC Anderton, A Kawamura, ... Protein & Cell 1 (1), 82-95, 2010 | 63 | 2010 |
| Discrimination between Bacterial Phenotypes using Glyco-Nanoparticles and the Impact of Polymer Coating on Detection Readouts MI Gibson, E Fullam, GS Besra, SJ Richards Journal of Materials Chemistry B, 2014 | 62 | 2014 |
| Divergence of cofactor recognition across evolution: coenzyme A binding in a prokaryotic arylamine N-acetyltransferase E Fullam, IM Westwood, MC Anderton, ED Lowe, E Sim, MEM Noble Journal of molecular biology 375 (1), 178-191, 2008 | 60 | 2008 |
| Arylamine N-acetyltransferases in mycobacteria E Sim, J Sandy, D Evangelopoulos, E Fullam, S Bhakta, I Westwood, ... Current drug metabolism 9 (6), 510, 2008 | 52 | 2008 |
| Temperature stability of proteins essential for the intracellular survival of Mycobacterium tuberculosis N Lack, A Kawamura, E Fullam, N Laurieri, S Beard, A Russell, ... Biochem. J 418, 369-378, 2009 | 50 | 2009 |
| Structure and function of the transketolase from Mycobacterium tuberculosis and comparison with the human enzyme E Fullam, F Pojer, T Bergfors, TA Jones, ST Cole Open Biology 2 (1), 2012 | 48 | 2012 |
| Multivalent Antimicrobial Polymer Nanoparticles Target Mycobacteria and Gram-Negative Bacteria by Distinct Mechanisms SJ Richards, K Isulfi, LE Wilkins, J Lipecki, E Fullam, MI Gibson Biomacromolecules, 2017 | 43 | 2017 |
| Piperidinols That Show Anti-Tubercular Activity as Inhibitors of Arylamine N-Acetyltransferase: An Essential Enzyme for Mycobacterial Survival Inside Macrophages A Abuhammad, E Fullam, ED Lowe, D Staunton, A Kawamura, ... PloS one 7 (12), e52790, 2012 | 36 | 2012 |
| Design, synthesis and structure-activity relationships of 3, 5-diaryl-1< i> H</i>-pyrazoles as inhibitors of arylamine< i> N</i>-acetyltransferase E Fullam, J Talbot, A Abuhammed, I Westwood, SG Davies, AJ Russell, ... Bioorganic & Medicinal Chemistry Letters, 2013 | 35 | 2013 |
| Structural and functional determination of homologs of the Mycobacterium tuberculosis N-acetylglucosamine-6-phosphate deacetylase (NagA) MS Ahangar, CM Furze, CS Guy, C Cooper, KS Maskew, B Graham, ... Journal of Biological Chemistry, jbc. RA118. 002597, 2018 | 31 | 2018 |
| Probing the architecture of the Mycobacterium marinum arylamine N-acetyltransferase active site AM Abuhammad, ED Lowe, E Fullam, M Noble, EF Garman, E Sim Protein & Cell 1 (4), 384-392, 2010 | 28 | 2010 |
| Analysis of β-amino alcohols as inhibitors of the potential anti-tubercular target N-acetyltransferase E Fullam, A Abuhammad, DL Wilson, MC Anderton, SG Davies, ... Bioorganic & medicinal chemistry letters 21 (4), 1185-1190, 2011 | 25 | 2011 |
| Structural and functional analysis of the solute-binding protein UspC from Mycobacterium tuberculosis that is specific for amino sugars E Fullam, I Prokes, K Fütterer, GS Besra Open Biology 6 (6), 160105, 2016 | 24 | 2016 |
