Large-scale exome sequencing study implicates both developmental and functional changes in the neurobiology of autism FK Satterstrom, JA Kosmicki, J Wang, MS Breen, S De Rubeis, JY An, ... Cell 180 (3), 568-584. e23, 2020 | 1692 | 2020 |
Epistasis as the primary factor in molecular evolution MS Breen, C Kemena, PK Vlasov, C Notredame, FA Kondrashov Nature 490 (7421), 535-538, 2012 | 427 | 2012 |
Gene networks specific for innate immunity define post-traumatic stress disorder MS Breen, AX Maihofer, SJ Glatt, DS Tylee, SD Chandler, MT Tsuang, ... Molecular psychiatry 20 (12), 1538-1545, 2015 | 197 | 2015 |
Large-scale proteomic analysis of human brain identifies proteins associated with cognitive trajectory in advanced age AP Wingo, EB Dammer, MS Breen, BA Logsdon, DM Duong, ... Nature communications 10 (1), 1619, 2019 | 159 | 2019 |
PTSD blood transcriptome mega-analysis: shared inflammatory pathways across biological sex and modes of trauma MS Breen, DS Tylee, AX Maihofer, TC Neylan, D Mehta, EB Binder, ... Neuropsychopharmacology 43 (3), 469-481, 2018 | 112 | 2018 |
Gene expression analysis of TIL rich HPV-driven head and neck tumors reveals a distinct B-cell signature when compared to HPV independent tumors O Wood, J Woo, G Seumois, N Savelyeva, KJ McCann, D Singh, T Jones, ... Oncotarget 7 (35), 56781, 2016 | 107 | 2016 |
Whole-genome and RNA sequencing reveal variation and transcriptomic coordination in the developing human prefrontal cortex DM Werling, S Pochareddy, J Choi, JY An, B Sheppard, M Peng, Z Li, ... Cell reports 31 (1), 2020 | 94 | 2020 |
Global landscape and genetic regulation of RNA editing in cortical samples from individuals with schizophrenia MS Breen, A Dobbyn, Q Li, P Roussos, GE Hoffman, E Stahl, A Chess, ... Nature neuroscience 22 (9), 1402-1412, 2019 | 66 | 2019 |
MW State, AE Cicek, ME Talkowski, DJ Cutler, B. Devlin, SJ Sanders, K. Roeder, MJ Daly, JD Buxbaum, Large-scale exome sequencing study implicates both developmental and … FK Satterstrom, JA Kosmicki, J Wang, MS Breen, S De Rubeis, JY An, ... Cell 180 (568-584), e23, 2020 | 58* | 2020 |
Lithium-responsive genes and gene networks in bipolar disorder patient-derived lymphoblastoid cell lines MS Breen, CH White, T Shekhtman, K Lin, D Looney, CH Woelk, ... The pharmacogenomics journal 16 (5), 446-453, 2016 | 53 | 2016 |
Acute psychological stress induces short-term variable immune response MS Breen, N Beliakova-Bethell, LR Mujica-Parodi, JM Carlson, ... Brain, Behavior, and Immunity 53, 172-182, 2016 | 51 | 2016 |
Analysis of genetically regulated gene expression identifies a prefrontal PTSD gene, SNRNP35, specific to military cohorts LM Huckins, C Chatzinakos, MS Breen, J Hartmann, T Klengel, ... Cell reports 31 (9), 2020 | 50 | 2020 |
Novel genes for autism implicate both excitatory and inhibitory cell lineages in risk FK Satterstrom, JA Kosmicki, J Wang, MS Breen, SD Rubeis, JY An, ... BioRxiv, 484113, 2018 | 49 | 2018 |
Candidate gene networks and blood biomarkers of methamphetamine-associated psychosis: an integrative RNA-sequencing report MS Breen, A Uhlmann, CM Nday, SJ Glatt, M Mitt, A Metsalpu, DJ Stein, ... Translational psychiatry 6 (5), e802-e802, 2016 | 44 | 2016 |
Cell-type-specific impact of glucocorticoid receptor activation on the developing brain: a cerebral organoid study C Cruceanu, L Dony, AC Krontira, DS Fischer, S Roeh, R Di Giaimo, ... American Journal of Psychiatry 179 (5), 375-387, 2022 | 42 | 2022 |
Episignatures stratifying Helsmoortel-Van Der Aa syndrome show modest correlation with phenotype MS Breen, P Garg, L Tang, D Mendonca, T Levy, M Barbosa, AB Arnett, ... The American Journal of Human Genetics 107 (3), 555-563, 2020 | 40 | 2020 |
Gene expression in cord blood links genetic risk for neurodevelopmental disorders with maternal psychological distress and adverse childhood outcomes MS Breen, AP Wingo, N Koen, KA Donald, HJ Zar, KJ Ressler, ... Brain, Behavior, and Immunity, S0889-1591(18)30189-2, 2018 | 38 | 2018 |
Differential transcriptional response following glucocorticoid activation in cultured blood immune cells: a novel approach to PTSD biomarker development MS Breen, LM Bierer, NP Daskalakis, HN Bader, I Makotkine, ... Translational psychiatry 9 (1), 201, 2019 | 34 | 2019 |
B7-CD28 co-stimulation modulates central tolerance via thymic clonal deletion and Treg generation through distinct mechanisms M Watanabe, Y Lu, M Breen, RJ Hodes Nature Communications 11 (1), 6264, 2020 | 33 | 2020 |
Transcriptional signatures of participant-derived neural progenitor cells and neurons implicate altered Wnt signaling in Phelan-McDermid syndrome and autism MS Breen, A Browne, GE Hoffman, S Stathopoulos, K Brennand, ... Molecular autism 11, 1-23, 2020 | 32 | 2020 |