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Robert E MacLaren
Robert E MacLaren
Verified email at eye.ox.ac.uk - Homepage
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Cited by
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Retinal repair by transplantation of photoreceptor precursors
RE MacLaren, RA Pearson, A MacNeil, RH Douglas, TE Salt, M Akimoto, ...
Nature 444 (7116), 203-207, 2006
12982006
Retinal gene therapy in patients with choroideremia: initial findings from a phase 1/2 clinical trial
RE MacLaren, M Groppe, AR Barnard, CL Cottriall, T Tolmachova, ...
The Lancet 383 (9923), 1129-1137, 2014
8682014
Effective gene therapy with nonintegrating lentiviral vectors
RJ Yánez-Munoz, KS Balaggan, A MacNeil, SJ Howe, M Schmidt, ...
Nature medicine 12 (3), 348-353, 2006
5682006
Subretinal visual implant alpha IMS–clinical trial interim report
K Stingl, KU Bartz-Schmidt, D Besch, CK Chee, CL Cottriall, F Gekeler, ...
Vision research 111, 149-160, 2015
4012015
Comprehensive rare variant analysis via whole-genome sequencing to determine the molecular pathology of inherited retinal disease
KJ Carss, G Arno, M Erwood, J Stephens, A Sanchis-Juan, S Hull, K Megy, ...
The American Journal of Human Genetics 100 (1), 75-90, 2017
3922017
Reversal of end-stage retinal degeneration and restoration of visual function by photoreceptor transplantation
MS Singh, P Charbel Issa, R Butler, C Martin, DM Lipinski, S Sekaran, ...
Proceedings of the National Academy of Sciences 110 (3), 1101-1106, 2013
2932013
The drusenlike phenotype in aging Ccl2-knockout mice is caused by an accelerated accumulation of swollen autofluorescent subretinal macrophages
UFO Luhmann, S Robbie, PMG Munro, SE Barker, Y Duran, V Luong, ...
Investigative ophthalmology & visual science 50 (12), 5934-5943, 2009
2512009
Half-dose photodynamic therapy versus high-density subthreshold micropulse laser treatment in patients with chronic central serous chorioretinopathy: the PLACE trial
EHC van Dijk, S Fauser, MB Breukink, R Blanco-Garavito, ...
Ophthalmology 125 (10), 1547-1555, 2018
2422018
Transplanted photoreceptor precursors transfer proteins to host photoreceptors by a mechanism of cytoplasmic fusion
MS Singh, J Balmer, AR Barnard, SA Aslam, D Moralli, CM Green, ...
Nature communications 7 (1), 13537, 2016
2292016
Initial results from a first-in-human gene therapy trial on X-linked retinitis pigmentosa caused by mutations in RPGR
J Cehajic-Kapetanovic, K Xue, C Martinez-Fernandez de la Camara, ...
Nature medicine 26 (3), 354-359, 2020
2282020
Visual acuity after retinal gene therapy for choroideremia
TL Edwards, JK Jolly, M Groppe, AR Barnard, CL Cottriall, T Tolmachova, ...
New England Journal of Medicine 374 (20), 1996-1998, 2016
2192016
CRISPR-Cas9 DNA base-editing and prime-editing
A Kantor, ME McClements, RE MacLaren
International journal of molecular sciences 21 (17), 6240, 2020
2182020
Interim results of a multicenter trial with the new electronic subretinal implant alpha AMS in 15 patients blind from inherited retinal degenerations
K Stingl, R Schippert, KU Bartz-Schmidt, D Besch, CL Cottriall, ...
Frontiers in neuroscience 11, 445, 2017
1972017
Pharmacological disruption of the outer limiting membrane leads to increased retinal integration of transplanted photoreceptor precursors
EL West, RA Pearson, M Tschernutter, JC Sowden, RE MacLaren, RR Ali
Experimental eye research 86 (4), 601-611, 2008
1912008
Immunological instability of persistent adenovirus vectors in the brain: peripheral exposure to vector leads to renewed inflammation, reduced gene expression, and demyelination
AP Byrnes, RE MacLaren, HM Charlton
Journal of Neuroscience 16 (9), 3045-3055, 1996
1871996
First-in-human study of the safety and viability of intraocular robotic surgery
TL Edwards, K Xue, HCM Meenink, MJ Beelen, GJL Naus, MP Simunovic, ...
Nature biomedical engineering 2 (9), 649-656, 2018
1842018
Assessment of the electronic retinal implant alpha AMS in restoring vision to blind patients with end-stage retinitis pigmentosa
TL Edwards, CL Cottriall, K Xue, MP Simunovic, JD Ramsden, E Zrenner, ...
Ophthalmology 125 (3), 432-443, 2018
1702018
Beneficial effects on vision in patients undergoing retinal gene therapy for choroideremia
K Xue, JK Jolly, AR Barnard, A Rudenko, AP Salvetti, MI Patrício, ...
Nature medicine 24 (10), 1507-1512, 2018
1692018
Autologous transplantation of the retinal pigment epithelium and choroid in the treatment of neovascular age-related macular degeneration
RE MacLaren, GS Uppal, KS Balaggan, A Tufail, PMG Munro, AB Milliken, ...
Ophthalmology 114 (3), 561-570. e2, 2007
1692007
Retinal stem cell transplantation: Balancing safety and potential
MS Singh, SS Park, TA Albini, MV Canto-Soler, H Klassen, RE MacLaren, ...
Progress in retinal and eye research 75, 100779, 2020
1642020
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