|FK228 (depsipeptide) as a natural prodrug that inhibits class I histone deacetylases|
R Furumai, A Matsuyama, N Kobashi, KH Lee, M Nishiyama, H Nakajima, ...
Cancer research 62 (17), 4916-4921, 2002
|Histone deacetylase as a new target for cancer chemotherapy|
M Yoshida, R Furumai, M Nishiyama, Y Komatsu, N Nishino, S Horinouchi
Cancer chemotherapy and pharmacology 48 (1), S20-S26, 2001
|X-ray structure and site-directed mutagenesis of a nitrite reductase from Alcaligenes faecalis S-6: roles of two copper atoms in nitrite reduction|
M Kukimoto, M Nishiyama, MEP Murphy, S Turley, ET Adman, ...
Biochemistry 33 (17), 5246-5252, 1994
|Determinants of protein thermostability observed in the 1.9-. ANG. crystal structure of malate dehydrogenase from the thermophilic bacterium Thermus flavus|
CA Kelly, M Nishiyama, Y Ohnishi, T Beppu, JJ Birktoft
Biochemistry 32 (15), 3913-3922, 1993
|Primary structure of AfsR, a global regulatory protein for secondary metabolite formation in Streptomyces coelicolor A3(2)|
S Horinouchi, M Kito, M Nishiyama, K Furuya, SK Hong, K Miyake, ...
Gene 95 (1), 49-56, 1990
|Amidase coupled with low‐molecular‐mass nitrile hydratase from Rhodococcus rhodochrous J1: Sequencing and expression of the gene and purification and …|
M Kobayashi, H KOMEDA, T NAGASAWA, M NISHIYAMA, ...
European journal of biochemistry 217 (1), 327-336, 1993
|Cloning and characterization of genes responsible for metabolism of nitrile compounds from Pseudomonas chlororaphis B23.|
M Nishiyama, S Horinouchi, M Kobayashi, T Nagasawa, H Yamada, ...
Journal of bacteriology 173 (8), 2465-2472, 1991
|Cloning, nucleotide sequence and expression in Escherichia coli of two cobalt-containing nitrile hydratase genes from Rhodococcus rhodochrous J1|
M Kobayashi, M Nishiyama, T Nagasawa, S Horinouchi, T Beppu, ...
Biochimica et Biophysica Acta (BBA)-Gene Structure and Expression 1129 (1 …, 1991
|Package medium system having URL hyper-linked to data in removable storage|
T Ozaki, T Kuwabara, T Oda, M Nishiyama, T Takeuchi, J Miyauchi
US Patent 5,991,798, 1999
|Primary structure of nitrile hydratase deduced from the nucleotide sequence of a Rhodococcus species and its expression in Escherichia coli|
O Ikehata, M NISHIYAMA, S HORINOUCHI, T BEPPU
European journal of biochemistry 181 (3), 563-570, 1989
|A prokaryotic gene cluster involved in synthesis of lysine through the amino adipate pathway: a key to the evolution of amino acid biosynthesis|
H Nishida, M Nishiyama, N Kobashi, T Kosuge, T Hoshino, H Yamane
Genome Research 9 (12), 1175-1183, 1999
|Catalytic roles for two water bridged residues (Asp-98 and His-255) in the active site of copper-containing nitrite reductase|
MJ Boulanger, M Kukimoto, M Nishiyama, S Horinouchi, MEP Murphy
Journal of Biological Chemistry 275 (31), 23957-23964, 2000
|Molecular cloning and characterization of a cDNA encoding ent‐cassa‐12,15‐diene synthase, a putative diterpenoid phytoalexin biosynthetic enzyme, from …|
EM Cho, A Okada, H Kenmoku, K Otomo, T Toyomasu, W Mitsuhashi, ...
The Plant Journal 37 (1), 1-8, 2004
|Structure of Alcaligenes faecalis nitrite reductase and a copper site mutant, M150E, that contains zinc|
MEP Murphy, S Turley, M Kukimoto, M Nishiyama, S Horinouchi, H Sasaki, ...
Biochemistry 34 (38), 12107-12117, 1995
|Nucleotide sequence of the streptothricin acetyltransferase gene from Streptomyces lavendulae and its expression in heterologous hosts.|
S Horinouchi, K Furuya, M Nishiyama, H Suzuki, T Beppu
Journal of bacteriology 169 (5), 1929-1937, 1987
|Development of a host-vector system in a Rhodococcus strain and its use for expression of the cloned nitrile hydratase gene cluster|
Y Hashimoto, M Nishiyama, F Yu, I Watanabe, S Horinouchi, T Beppu
Microbiology 138 (5), 1003-1010, 1992
|Nucleotide sequence of the malate dehydrogenase gene of Thermus flavus and its mutation directing an increase in enzyme activity.|
M Nishiyama, N Matsubara, K Yamamoto, S Iijima, T Uozumi, T Beppu
Journal of Biological Chemistry 261 (30), 14178-14183, 1986
|A novel− 66T/C polymorphism in FcεRI α-chain promoter affecting the transcription activity: possible relationship to allergic diseases|
M Hasegawa, C Nishiyama, M Nishiyama, Y Akizawa, K Mitsuishi, T Ito, ...
The Journal of Immunology 171 (4), 1927-1933, 2003
|Regulation of human FcεRI α-chain gene expression by multiple transcription factors|
C Nishiyama, M Hasegawa, M Nishiyama, K Takahashi, Y Akizawa, ...
The Journal of Immunology 168 (9), 4546-4552, 2002
|Site-Directed Mutants of Pseudoazurin: Explanation of Increased Redox Potentials from X-ray Structures and from Calculation of Redox Potential Differences,|
CAP Libeu, M Kukimoto, M Nishiyama, S Horinouchi, ET Adman
Biochemistry 36 (43), 13160-13179, 1997