Nicola Conran
Nicola Conran
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Altered levels of cytokines and inflammatory mediators in plasma and leukocytes of sickle cell anemia patients and effects of hydroxyurea therapy
C Lanaro, CF Franco‐Penteado, DM Albuqueque, STO Saad, N Conran, ...
Journal of leukocyte biology 85 (2), 235-242, 2009
Newer aspects of the pathophysiology of sickle cell disease vaso-occlusion
N Conran, CF Franco-Penteado, FF Costa
Hemoglobin 33 (1), 1-16, 2009
Chronic myeloid leukemia patients with the e13a2 BCR-ABL fusion transcript have inferior responses to imatinib compared to patients with the e14a2 transcript
CM Lucas, RJ Harris, A Giannoudis, A Davies, K Knight, SJ Watmough, ...
haematologica 94 (10), 1362, 2009
Hydroxyurea and a cGMP-amplifying agent have immediate benefits on acute vaso-occlusive events in sickle cell disease mice
CB Almeida, C Scheiermann, JE Jang, C Prophete, FF Costa, N Conran, ...
Blood 120 (14), 2879-2888, 2012
Red cell DAMPs and inflammation
R Mendonça, AAA Silveira, N Conran
Inflammation Research 65 (9), 665-678, 2016
Increased adhesive properties of neutrophils in sickle cell disease may be reversed by pharmacological nitric oxide donation.
AA Canalli, CF Franco-Penteado, STO Saad, N Conran, FF Costa
haematologica, 2008
Hemoglobin disorders and endothelial cell interactions
N Conran, FF Costa
Clinical biochemistry 42 (18), 1824-1838, 2009
Inflammation in sickle cell disease
N Conran, JD Belcher
Clinical hemorheology and microcirculation 68 (2-3), 263-299, 2018
Anemia falciforme
Zago MA, Falcão RP, Pasquini R. Hematologia fundamentos e prática. São Paulo …, 2001
JAK2 p. V617F allele burden in myeloproliferative neoplasms one month after allogeneic stem cell transplantation significantly predicts outcome and risk of relapse
T Lange, A Edelmann, U Siebolts, R Krahl, C Nehring, N Jäkel, M Cross, ...
haematologica 98 (5), 722, 2013
Effect of cytokines and chemokines on sickle neutrophil adhesion to fibronectin
A Assis, N Conran, AA Canalli, I Lorand-Metze, STO Saad, FF Costa
Acta haematologica 113 (2), 130-136, 2005
Acute hemolytic vascular inflammatory processes are prevented by nitric oxide replacement or a single dose of hydroxyurea
CB Almeida, LEB Souza, FC Leonardo, FTM Costa, CC Werneck, ...
Blood, The Journal of the American Society of Hematology 126 (6), 711-720, 2015
Increased soluble guanylate cyclase activity in the red blood cells of sickle cell patients
N Conran, C Oresco‐Santos, HC Acosta, A Fattori, STO Saad, FF Costa
British journal of haematology 124 (4), 547-554, 2004
Increased levels of soluble ICAM‐1 in the plasma of sickle cell patients are reversed by hydroxyurea
N Conran, A Fattori, STO Saad, FF Costa
American journal of hematology 76 (4), 343-347, 2004
Therapy with hydroxyurea is associated with reduced adhesion molecule gene and protein expression in sickle red cells with a concomitant reduction in adhesive properties
S Gambero, AA Canalli, F Traina, DM Albuquerque, STO Saad, FF Costa, ...
European journal of haematology 78 (2), 144-151, 2007
Nitric oxide has a role in regulating VLA-4-integrin expression on the human neutrophil cell surface
N Conran, A Gambero, HHA Ferreira, E Antunes, G de Nucci
Biochemical pharmacology 66 (1), 43-50, 2003
Nitric oxide regulates human eosinophil adhesion mechanisms in vitro by changing integrin expression and activity on the eosinophil cell surface
N Conran, HHA Ferreira, I Lorand‐Metze, SM Thomazzi, E Antunes, ...
British journal of pharmacology 134 (3), 632-638, 2001
Endothelial activation by platelets from sickle cell anemia patients
R Proença-Ferreira, AF Brugnerotto, VT Garrido, VM Dominical, DM Vital, ...
PloS one 9 (2), e89012, 2014
Leukocyte numbers correlate with plasma levels of granulocyte–macrophage colony-stimulating factor in sickle cell disease
N Conran, STO Saad, FF Costa, T Ikuta
Annals of hematology 86 (4), 255-261, 2007
Hydroxyurea is associated with reductions in hypercoagulability markers in sickle cell anemia
MP Colella, EV De Paula, N Conran, JA Machado‐Neto, ...
Journal of Thrombosis and Haemostasis 10 (9), 1967-1970, 2012
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