Philip Cohen
Philip Cohen
MRC Protein Phosphorylation Unit, University of Dundee Scotland
Verified email at
Cited by
Cited by
Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
DAE Cross, DR Alessi, P Cohen, M Andjelkovich, BA Hemmings
Nature 378 (6559), 785-789, 1995
Specificity and mechanism of action of some commonly used protein kinase inhibitors
SP Davies, H Reddy, M Caivano, P Cohen
Biochemical Journal 351 (1), 95-105, 2000
PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo
DR Alessi, A Cuenda, P Cohen, DT Dudley, AR Saltiel
Journal of Biological Chemistry 270 (46), 27489-27494, 1995
Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Bα
DR Alessi, SR James, CP Downes, AB Holmes, PRJ Gaffney, CB Reese, ...
Current biology 7 (4), 261-269, 1997
Mechanism of activation of protein kinase B by insulin and IGF‐1.
DR Alessi, M Andjelkovic, B Caudwell, P Cron, N Morrice, P Cohen, ...
The EMBO journal 15 (23), 6541-6551, 1996
The ground state of embryonic stem cell self-renewal
QL Ying, J Wray, J Nichols, L Batlle-Morera, B Doble, J Woodgett, ...
nature 453 (7194), 519-523, 2008
The structure and regulation of protein phosphatases
P Cohen
Annual review of biochemistry 58 (1), 453-508, 1989
The selectivity of protein kinase inhibitors: a further update
J Bain, L Plater, M Elliott, N Shpiro, CJ Hastie, H Mclauchlan, I Klevernic, ...
Biochemical Journal 408 (3), 297-315, 2007
Protein kinases—the major drug targets of the twenty-first century?
P Cohen
Nature reviews Drug discovery 1 (4), 309-315, 2002
SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1
A Cuenda, J Rouse, YN Doza, R Meier, P Cohen, TF Gallagher, ...
FEBS letters 364 (2), 229-233, 1995
A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins
J Rouse, P Cohen, S Trigon, M Morange, A Alonso-Llamazares, ...
Cell 78 (6), 1027-1037, 1994
Cyanobacterial microcystin-LR is a potent and specific inhibitor of protein phosphatases 1 and 2A from both mammals and higher plants
C MacKintosh, KA Beattie, S Klumpp, P Cohen, GA Codd
FEBS letters 264 (2), 187-192, 1990
The renaissance of GSK3
P Cohen, S Frame
Nature reviews Molecular cell biology 2 (10), 769-776, 2001
GSK3 takes centre stage more than 20 years after its discovery
S Frame, P Cohen
Biochemical Journal 359 (1), 1-16, 2001
The specificities of protein kinase inhibitors: an update
J Bain, H McLauchlan, M Elliott, P Cohen
Biochemical Journal 371 (1), 199-204, 2003
Okadaic acid: a new probe for the study of cellular regulation
P Cohen, CFB Holmes, Y Tsukitani
Trends in biochemical sciences 15 (3), 98-102, 1990
The regulation of protein function by multisite phosphorylation–a 25 year update
P Cohen
Trends in biochemical sciences 25 (12), 596-601, 2000
The origins of protein phosphorylation
P Cohen
Nature cell biology 4 (5), E127-E130, 2002
Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1
JA Le Good, WH Ziegler, DB Parekh, DR Alessi, P Cohen, PJ Parker
Science 281 (5385), 2042-2045, 1998
The role of protein phosphorylation in neural and hormonal control of cellular activity
P Cohen
Nature 296 (5858), 613-620, 1982
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