Ignacio Vázquez-García
Ignacio Vázquez-García
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The repertoire of mutational signatures in human cancer
LB Alexandrov, J Kim, NJ Haradhvala, MN Huang, AW Tian Ng, Y Wu, ...
Nature 578 (7793), 94-101, 2020
Pan-cancer analysis of whole genomes
Nature 578 (7793), 82-93, 2020
The evolutionary history of 2,658 cancers
M Gerstung, C Jolly, I Leshchiner, SC Dentro, S Gonzalez, D Rosebrock, ...
Nature 578 (7793), 122-128, 2020
Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes
SC Dentro, I Leshchiner, K Haase, M Tarabichi, J Wintersinger, ...
Cell 184 (8), 2239-2254. e39, 2021
High-definition reconstruction of clonal composition in cancer
A Fischer, I Vázquez-García, CJR Illingworth, V Mustonen
Cell Reports 7 (5), 1740–1752, 2014
Clonal Decomposition and DNA Replication States Defined by Scaled Single-Cell Genome Sequencing
E Laks, A McPherson, H Zahn, D Lai, A Steif, J Brimhall, J Biele, B Wang, ...
Cell 179 (5), 1207-1221. e22, 2019
Three-dimensional imaging mass cytometry for highly multiplexed molecular and cellular mapping of tissues and the tumor microenvironment
L Kuett, R Catena, A Özcan, A Plüss, P Schraml, H Moch, N de Souza, ...
Nature Cancer 3 (1), 122-133, 2022
Multimodal data integration using machine learning improves risk stratification of high-grade serous ovarian cancer
KM Boehm, EA Aherne, L Ellenson, I Nikolovski, M Alghamdi, ...
Nature Cancer 3 (6), 723-733, 2022
Clonal fitness inferred from time-series modelling of single-cell cancer genomes
S Salehi, F Kabeer, N Ceglia, M Andronescu, MJ Williams, KR Campbell, ...
Nature 595 (7868), 585-590, 2021
Ovarian cancer mutational processes drive site-specific immune evasion
I Vázquez-García, F Uhlitz, N Ceglia, JLP Lim, M Wu, N Mohibullah, ...
Nature 612 (7941), 778-786, 2022
A community effort to create standards for evaluating tumor subclonal reconstruction
A Salcedo, M Tarabichi, SMG Espiritu, AG Deshwar, M David, NM Wilson, ...
Nature biotechnology 38 (1), 97-107, 2020
The value of monitoring to control evolving populations
A Fischer, I Vázquez-García, V Mustonen
Proceedings of the National Academy of Sciences 112 (4), 1007–1012, 2015
Single-cell genomic variation induced by mutational processes in cancer
T Funnell, CH O’Flanagan, MJ Williams, A McPherson, S McKinney, ...
Nature 612 (7938), 106-115, 2022
Clonal Heterogeneity Influences the Fate of New Adaptive Mutations
I Vázquez-García, F Salinas, J Li, A Fischer, B Barré, J Hallin, A Bergström, ...
Cell Reports 21 (3), 732-744, 2017
BRCA Mutations, Homologous DNA Repair Deficiency, Tumor Mutational Burden, and Response to Immune Checkpoint Inhibition in Recurrent Ovarian Cancer
YL Liu, P Selenica, Q Zhou, A Iasonos, M Callahan, NZ Feit, J Boland, ...
JCO Precision Oncology 4, 665-679, 2020
Contrasting the impact of cytotoxic and cytostatic drug therapies on tumour progression
JV Anttila, M Shubin, J Cairns, F Borse, Q Guo, T Mononen, ...
PLoS computational biology 15 (11), e1007493, 2019
Fundamental immune–oncogenicity trade-offs define driver mutation fitness
D Hoyos, R Zappasodi, I Schulze, Z Sethna, KC de Andrade, DF Bajorin, ...
Nature 606 (7912), 172-179, 2022
Shared molecular targets confer resistance over short and long evolutionary timescales
J Li, I Vázquez-García, K Persson, A González, JX Yue, B Barré, MN Hall, ...
Molecular biology and evolution 36 (4), 691-708, 2019
Evolutionary tracking of cancer haplotypes at single-cell resolution
MJ Williams, T Funnell, CH O’Flanagan, A McPherson, S Salehi, ...
Biorxiv, 2021.06. 04.447031, 2021
Pervasive intra-tumour heterogeneity and subclonal selection across cancer types
S Dentro, I Leshchiner, K Haase, J Wintersinger, A Deshwar, M Tarabichi, ...
Cancer Research 78 (13_Supplement), 3000-3000, 2018
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