| Cyclolignans as inhibitors of the insulin-like growth factor-1 receptor and malignant cell growth A Girnita, L Girnita, F Prete, A Bartolazzi, O Larsson, M Axelson Cancer research 64 (1), 236-242, 2004 | 431 | 2004 |
| Role of insulin-like growth factor 1 receptor signalling in cancer O Larsson, A Girnita, L Girnita British journal of cancer 92 (12), 2097-2101, 2005 | 311 | 2005 |
| Insulin-like growth factor-1 receptor in uveal melanoma: a predictor for metastatic disease and a potential therapeutic target C All-Ericsson, L Girnita, S Seregard, A Bartolazzi, MJ Jager, O Larsson Investigative ophthalmology & visual science 43 (1), 1-8, 2002 | 266 | 2002 |
| Mdm2-dependent ubiquitination and degradation of the insulin-like growth factor 1 receptor L Girnita, A Girnita, O Larsson Proceedings of the National Academy of Sciences 100 (14), 8247-8252, 2003 | 262 | 2003 |
| Something old, something new and something borrowed: emerging paradigm of insulin-like growth factor type 1 receptor (IGF-1R) signaling regulation L Girnita, C Worrall, SI Takahashi, S Seregard, A Girnita Cellular and molecular life sciences 71, 2403-2427, 2014 | 198 | 2014 |
| IGF-1 receptor tyrosine kinase inhibition by the cyclolignan PPP induces G2/M-phase accumulation and apoptosis in multiple myeloma cells T Strömberg, S Ekman, L Girnita, LY Dimberg, O Larsson, M Axelson, ... Blood 107 (2), 669-678, 2006 | 198 | 2006 |
| The cyclolignan PPP induces activation loop-specific inhibition of tyrosine phosphorylation of the insulin-like growth factor-1 receptor. Link to the phosphatidyl inositol-3 … D Vasilcanu, A Girnita, L Girnita, R Vasilcanu, M Axelson, O Larsson Oncogene 23 (47), 7854-7862, 2004 | 189 | 2004 |
| β-Arrestin is crucial for ubiquitination and down-regulation of the insulin-like growth factor-1 receptor by acting as adaptor for the MDM2 E3 ligase L Girnita, SK Shenoy, B Sehat, R Vasilcanu, A Girnita, RJ Lefkowitz, ... Journal of Biological Chemistry 280 (26), 24412-24419, 2005 | 168 | 2005 |
| Inhibiting the IGF-1 receptor tyrosine kinase with the cyclolignan PPP: an in vitro and in vivo study in the 5T33MM mouse model E Menu, H Jernberg-Wiklund, T Stromberg, H De Raeve, L Girnita, ... Blood 107 (2), 655-660, 2006 | 159 | 2006 |
| β-Arrestin and Mdm2 mediate IGF-1 receptor-stimulated ERK activation and cell cycle progression L Girnita, SK Shenoy, B Sehat, R Vasilcanu, D Vasilcanu, A Girnita, ... Journal of Biological Chemistry 282 (15), 11329-11338, 2007 | 152 | 2007 |
| The insulin-like growth factor-I receptor inhibitor picropodophyllin causes tumor regression and attenuates mechanisms involved in invasion of uveal melanoma cells. A Girnita, C All-Ericsson, MA Economou, K Astr√∂ m, M Axelson, ... Clinical cancer research: an official journal of the American Association …, 2006 | 136 | 2006 |
| Identification of c-Cbl as a new ligase for insulin-like growth factor-I receptor with distinct roles from Mdm2 in receptor ubiquitination and endocytosis B Sehat, S Andersson, L Girnita, O Larsson Cancer research 68 (14), 5669-5677, 2008 | 132 | 2008 |
| RETRACTED ARTICLE: Identification of the cathelicidin peptide LL-37 as agonist for the type I insulin-like growth factor receptor A Girnita, H Zheng, A Grönberg, L Girnita, M Ståhle Oncogene 31 (3), 352-365, 2012 | 113 | 2012 |
| Decrypting noncoding RNA interactions, structures, and functional networks M Fabbri, L Girnita, G Varani, GA Calin Genome research 29 (9), 1377-1388, 2019 | 111 | 2019 |
| Selective recruitment of G protein-coupled receptor kinases (GRKs) controls signaling of the insulin-like growth factor 1 receptor H Zheng, C Worrall, H Shen, T Issad, S Seregard, A Girnita, L Girnita Proceedings of the National Academy of Sciences 109 (18), 7055-7060, 2012 | 111 | 2012 |
| Increased expression of insulin-like growth factor I receptor in malignant cells expressing aberrant p53: functional impact L Girnita, A Girnita, B Brodin, Y Xie, G Nilsson, A Dricu, J Lundeberg, ... Cancer research 60 (18), 5278-5283, 2000 | 111 | 2000 |
| Insulin-like growth factor type 1 receptor expression correlates to good prognosis in highly malignant soft tissue sarcoma J Ahlén, J Wejde, O Brosjö, A Von Rosen, WH Weng, L Girnita, ... Clinical cancer research 11 (1), 206-216, 2005 | 101 | 2005 |
| Expression of insulin-like growth factor-1 receptor (IGF-1R) and p27Kip1 in melanocyte tumors: a potential regulatory role of IGF-1 pathway in distribution of p27Kip1 between … L Kanter-Lewensohn, A Dricu, L Girnita, J Wejde, O Larsson Growth Factors 17 (3), 193-202, 2000 | 101 | 2000 |
| Targeting the insulin-like growth factor-1 receptor by picropodophyllin as a treatment option for glioblastoma S Yin, A Girnita, T Strömberg, Z Khan, S Andersson, H Zheng, C Ericsson, ... Neuro-oncology 12 (1), 19-27, 2010 | 97 | 2010 |
| c-Kit–dependent growth of uveal melanoma cells: a potential therapeutic target? C All-Ericsson, L Girnita, A Müller-Brunotte, B Brodin, S Seregard, ... Investigative ophthalmology & visual science 45 (7), 2075-2082, 2004 | 95 | 2004 |
Caitrin Crudden, Ph.D.Postdoctoral Researcher, Vrije University, AmsterdamVerified email at vu.nl
