| PD-L1 (B7-H1) Competes with the RNA Exosome to Regulate the DNA Damage Response and Can Be Targeted to Sensitize to Radiation or Chemotherapy X Tu, B Qin, Y Zhang, C Zhang, M Kahila, S Nowsheen, P Yin, J Yuan, ... Molecular cell, 2019 | 171 | 2019 |
| UFL1 promotes histone H4 ufmylation and ATM activation B Qin, J Yu, S Nowsheen, M Wang, X Tu, T Liu, H Li, L Wang, Z Lou Nature communications 10 (1), 1242, 2019 | 115 | 2019 |
| Long Noncoding RNA p53-Stabilizing and Activating RNA Promotes p53 Signaling by Inhibiting Heterogeneous Nuclear Ribonucleoprotein K deSUMOylation and Suppresses Hepatocellular … G Qin, X Tu, H Li, P Cao, X Chen, J Song, H Han, Y Li, B Guo, L Yang, ... HEPATOLOGY, 2019 | 111 | 2019 |
| Functional polymorphisms of the CCL2 and MBL genes cumulatively increase susceptibility to severe acute respiratory syndrome coronavirus infection X Tu, WP Chong, Y Zhai, H Zhang, F Zhang, S Wang, W Liu, M Wei, ... Journal of Infection 71 (1), 101-109, 2015 | 111 | 2015 |
| ATR Inhibition Is a Promising Radiosensitizing Strategy for Triple-Negative Breast Cancer X Tu, MM Kahila, Q Zhou, J Yu, KR Kalari, L Wang, WS Harmsen, J Yuan, ... Molecular cancer therapeutics 17 (11), 2462-2472, 2018 | 76 | 2018 |
| Regulation of sister chromatid cohesion by nuclear PD-L1 J Yu, B Qin, AM Moyer, S Nowsheen, X Tu, H Dong, JC Boughey, ... Cell Research, 1-12, 2020 | 72 | 2020 |
| USP20 positively regulates tumorigenesis and chemoresistance through β-catenin stabilization C Wu, K Luo, F Zhao, P Yin, Y Song, M Deng, J Huang, Y Chen, L Li, ... Cell Death & Differentiation 25 (10), 1855, 2018 | 66 | 2018 |
| Genome-wide association study identifies 8p21. 3 associated with persistent hepatitis B virus infection among Chinese Y Li, L Si, Y Zhai, Y Hu, Z Hu, JX Bei, B Xie, Q Ren, P Cao, F Yang, ... Nature communications 7, 11664, 2016 | 62 | 2016 |
| The bromodomain containing protein BRD-9 orchestrates RAD51–RAD54 complex formation and regulates homologous recombination-mediated repair Q Zhou, J Huang, C Zhang, F Zhao, W Kim, X Tu, Y Zhang, S Nowsheen, ... Nature communications 11 (1), 1-13, 2020 | 54 | 2020 |
| Reciprocal regulation of RIG-I and XRCC4 connects DNA repair with RIG-I immune signaling G Guo, M Gao, X Gao, B Zhu, J Huang, X Tu, W Kim, F Zhao, Q Zhou, ... Nature communications 12 (1), 1-15, 2021 | 44 | 2021 |
| USP39 regulates DNA damage response and chemo-radiation resistance by deubiquitinating and stabilizing CHK2 J Wu, Y Chen, G Geng, L Li, P Yin, S Nowsheen, Y Li, C Wu, J Liu, F Zhao, ... Cancer letters 449, 114-124, 2019 | 43 | 2019 |
| MET amplification attenuates lung tumor response to immunotherapy by inhibiting STING Y Zhang, Q Yang, X Zeng, M Wang, S Dong, B Yang, X Tu, T Wei, W Xie, ... Cancer Discovery, 2021 | 42 | 2021 |
| CHK2-FOXK axis promotes transcriptional control of autophagy programs Y Chen, J Wu, G Liang, G Geng, F Zhao, P Yin, S Nowsheen, C Wu, Y Li, ... Science Advances 6 (1), eaax5819, 2020 | 42 | 2020 |
| Tandem Deubiquitination and Acetylation of SPRTN Promotes DNA-Protein Crosslink Repair and Protects against Aging J Huang, Q Zhou, M Gao, S Nowsheen, F Zhao, W Kim, Q Zhu, Y Kojima, ... Molecular Cell, 2020 | 38 | 2020 |
| A novel UCHL 3 inhibitor, perifosine, enhances PARP inhibitor cytotoxicity through inhibition of homologous recombination-mediated DNA double strand break repair Z Song, X Tu, Q Zhou, J Huang, Y Chen, J Liu, SB Lee, W Kim, ... Cell death & disease 10 (6), 398, 2019 | 38 | 2019 |
| ASTE1 promotes shieldin-complex-mediated DNA repair by attenuating end resection F Zhao, W Kim, H Gao, C Liu, Y Zhang, Y Chen, M Deng, Q Zhou, ... Nature Cell Biology 23 (8), 894-904, 2021 | 30 | 2021 |
| METTL16 antagonizes MRE11-mediated DNA end resection and confers synthetic lethality to PARP inhibition in pancreatic ductal adenocarcinoma X Zeng, F Zhao, G Cui, Y Zhang, RA Deshpande, Y Chen, M Deng, ... Nature Cancer 3 (9), 1088-1104, 2022 | 28 | 2022 |
| Inhibition of ATM induces hypersensitivity to proton irradiation by upregulating toxic end joining Q Zhou, ME Howard, X Tu, Q Zhu, JM Denbeigh, NB Remmes, ... Cancer Research, 2021 | 23 | 2021 |
| PD-L1 promotes myofibroblastic activation of hepatic stellate cells by distinct mechanisms selective for TGF-β receptor I versus II L Sun, Y Wang, X Wang, A Navarro-Corcuera, S Ilyas, N Jalan-Sakrikar, ... Cell reports 38 (6), 2022 | 19 | 2022 |
| USP52 regulates DNA end resection and chemosensitivity through removing inhibitory ubiquitination from CtIP M Gao, G Guo, J Huang, JA Kloeber, F Zhao, M Deng, X Tu, W Kim, ... Nature communications 11 (1), 1-13, 2020 | 18 | 2020 |
