| Nitric oxide mediates aortic disease in mice deficient in the metalloprotease Adamts1 and in a mouse model of Marfan syndrome J Oller, N Méndez-Barbero, EJ Ruiz, S Villahoz, M Renard, LI Canelas, ... Nature medicine 23 (2), 200-212, 2017 | 154 | 2017 |
| Lgr6 labels a rare population of mammary gland progenitor cells that are able to originate luminal mammary tumours L Blaas, F Pucci, HA Messal, AB Andersson, E Josue Ruiz, M Gerling, ... Nature cell biology 18 (12), 1346-1356, 2016 | 83 | 2016 |
| Intranasal Cry1Ac protoxin is an effective mucosal and systemic carrier and adjuvant of Streptococcus pneumoniae polysaccharides in mice L Moreno-Fierros, EJ Ruiz-Medina, R Esquivel, R López-Revilla, ... Scand J Immunol 57 (1), 45-55, 2003 | 75 | 2003 |
| LUBAC determines chemotherapy resistance in squamous cell lung cancer EJ Ruiz, ME Diefenbacher, JK Nelson, R Sancho, F Pucci, A Chakraborty, ... Journal of Experimental Medicine 216 (2), 450-465, 2019 | 66 | 2019 |
| The p57 CDKi integrates stress signals into cell-cycle progression to promote cell survival upon stress M Joaquin, A Gubern, D González-Nuñez, EJ Ruiz, I Ferreiro, E de Nadal, ... EMBO J 31 (13), 2952-64, 2012 | 65 | 2012 |
| A paracrine network regulates the cross-talk between human lung stem cells and the stroma EJ Ruiz, F Oeztuerk-Winder, JJ Ventura Nat Commun 5, 3175, 2014 | 56 | 2014 |
| METTL3 promotes oxaliplatin resistance of gastric cancer CD133+ stem cells by promoting PARP1 mRNA stability H Li, C Wang, L Lan, L Yan, W Li, I Evans, EJ Ruiz, Q Su, G Zhao, W Wu, ... Cellular and Molecular Life Sciences 79 (3), 135, 2022 | 55 | 2022 |
| A two-step inactivation mechanism of Myt1 ensures CDK1/cyclin B activation and meiosis I entry EJ Ruiz, M Vilar, AR Nebreda Curr Biol 20 (8), 717-23, 2010 | 53 | 2010 |
| Meiotic inactivation of Xenopus Myt1 by CDK/XRINGO, but not CDK/cyclin, via site-specific phosphorylation EJ Ruiz, T Hunt, AR Nebreda Mol Cell 32 (2), 210-20, 2008 | 42 | 2008 |
| GREM1 is required to maintain cellular heterogeneity in pancreatic cancer L Lan, T Evan, H Li, A Hussain, EJ Ruiz, M Zaw Thin, RMM Ferreira, H Ps, ... Nature 607 (7917), 163-168, 2022 | 40 | 2022 |
| The functional interaction of 14-3-3 proteins with the ERK1/2 scaffold KSR1 occurs in an isoform-specific manner LR Jagemann, LG Pérez-Rivas, EJ Ruiz, JA Ranea, F Sánchez-Jiménez, ... J Biol Chem 283 (25), 17450-62, 2008 | 40 | 2008 |
| USP28 deletion and small-molecule inhibition destabilizes c-MYC and elicits regression of squamous cell lung carcinoma EJ Ruiz, A Pinto-Fernandez, AP Turnbull, L Lan, TM Charlton, HC Scott, ... Elife 10, e71596, 2021 | 33 | 2021 |
| A combination of neutral loss and targeted product ion scanning with two enzymatic digestions facilitates the comprehensive mapping of phosphorylation sites J Casado-Vela, EJ Ruiz, AR Nebreda, C JI Proteomics 7 (15), 2522-9, 2007 | 28 | 2007 |
| High expression of vinculin predicts poor prognosis and distant metastasis and associates with influencing tumor-associated NK cell infiltration and epithelial-mesenchymal … H Li, C Wang, L Lan, A Behrens, M Tomaschko, J Ruiz, Q Su, G Zhao, ... Aging (Albany NY) 13 (4), 5197, 2021 | 24 | 2021 |
| JunD, not c-Jun, is the AP-1 transcription factor required for Ras-induced lung cancer EJ Ruiz, L Lan, ME Diefenbacher, EM Riising, C Da Costa, A Chakraborty, ... JCI insight 6 (13), 2021 | 21 | 2021 |
| ATMIN Is a Tumor Suppressor Gene in Lung Adenocarcinoma H Foster, EJ Ruiz, C Moore, GWH Stamp, EL Nye, N Li, Y Pan, Y He, ... Cancer research 79 (20), 5159-5166, 2019 | 15 | 2019 |
| Negative regulation of cell-cycle progression by RINGO/Speedy E. A Dinarina, EJ Ruiz, A O'Loghlen, S Mouron, L Perez, AR Nebreda Biochem J 410 (3), 535-42, 2008 | 14 | 2008 |
| PARP1 inhibitor combined with oxaliplatin efficiently suppresses oxaliplatin resistance in gastric cancer-derived organoids via homologous recombination and the base excision … H Li, C Wang, L Lan, W Wu, I Evans, EJ Ruiz, L Yan, Z Zhou, JM Oliveira, ... Frontiers in cell and developmental biology 9, 719192, 2021 | 11 | 2021 |
| p38α negatively regulates survival and malignant selection of transformed bronchioalveolar stem cells E Voisset, F Oeztuerk-Winder, EJ Ruiz, JJ Ventura PLoS One 8 (11), e78911, 2013 | 11 | 2013 |
| An intrinsic temporal order of c-JUN N-terminal phosphorylation regulates its activity by orchestrating co-factor recruitment CA Waudby, S Alvarez-Teijeiro, E Josue Ruiz, S Suppinger, N Pinotsis, ... Nature Communications 13 (1), 6133, 2022 | 9 | 2022 |
