Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression AM Khalil, M Guttman, M Huarte, M Garber, A Raj, DR Morales, K Thomas, ... Proceedings of the National Academy of Sciences 106 (28), 11667-11672, 2009 | 3259 | 2009 |
A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response M Huarte, M Guttman, D Feldser, M Garber, MJ Koziol, ... Cell 142 (3), 409-419, 2010 | 2389 | 2010 |
Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of β-secretase MA Faghihi, F Modarresi, AM Khalil, DE Wood, BG Sahagan, TE Morgan, ... Nature medicine 14 (7), 723, 2008 | 1538 | 2008 |
Emerging functional and mechanistic paradigms of mammalian long non-coding RNAs VA Moran, RJ Perera, AM Khalil Nucleic acids research 40 (14), 6391-6400, 2012 | 717 | 2012 |
A small molecule enhances RNA interference and promotes microRNA processing G Shan, Y Li, J Zhang, W Li, KE Szulwach, R Duan, MA Faghihi, AM Khalil, ... Nature biotechnology 26 (8), 933, 2008 | 284 | 2008 |
Dynamic histone modifications mark sex chromosome inactivation and reactivation during mammalian spermatogenesis AM Khalil, FZ Boyar, DJ Driscoll Proceedings of the National Academy of Sciences of the United States of …, 2004 | 199 | 2004 |
A novel RNA transcript with antiapoptotic function is silenced in fragile X syndrome AM Khalil, MA Faghihi, F Modarresi, SP Brothers, C Wahlestedt PLoS One 3 (1), e1486, 2008 | 197 | 2008 |
DNMT1-associated long non-coding RNAs regulate global gene expression and DNA methylation in colon cancer CR Merry, ME Forrest, JN Sabers, L Beard, XH Gao, M Hatzoglou, ... Human molecular genetics 24 (21), 6240-6253, 2015 | 176 | 2015 |
The functional characterization of long noncoding RNA SPRY4-IT1 in human melanoma cells J Mazar, W Zhao, AM Khalil, B Lee, J Shelley, SS Govindarajan, ... Oncotarget 5 (19), 8959, 2014 | 164 | 2014 |
Decapping of long noncoding RNAs regulates inducible genes S Geisler, L Lojek, AM Khalil, KE Baker, J Coller Molecular cell 45 (3), 279-291, 2012 | 159 | 2012 |
RNA–protein interactions in human health and disease AM Khalil, JL Rinn Seminars in cell & developmental biology 22 (4), 359-365, 2011 | 149 | 2011 |
Emerging roles for long non-coding RNAs in cancer and neurological disorders CN Niland, CR Merry, AM Khalil Frontiers in genetics 3, 25, 2012 | 116 | 2012 |
Regulation of the cancer epigenome by long non-coding RNAs ME Forrest, AM Khalil Cancer letters 407, 106-112, 2017 | 110 | 2017 |
Dynamic expression of long noncoding RNAs reveals their potential roles in spermatogenesis and fertility L Wichman, S Somasundaram, C Breindel, DM Valerio, JR McCarrey, ... Biology of reproduction 97 (2), 313-323, 2017 | 100 | 2017 |
Nucleosome occupancy landscape and dynamics at mouse recombination hotspots IV Getun, ZK Wu, AM Khalil, PRJ Bois EMBO reports 11 (7), 555-560, 2010 | 76 | 2010 |
Identification of mRNAs and lincRNAs associated with lung cancer progression using next-generation RNA sequencing from laser micro-dissected archival FFPE tissue specimens ML Morton, X Bai, CR Merry, PA Linden, AM Khalil, RS Leidner, ... Lung Cancer 85 (1), 31-39, 2014 | 57 | 2014 |
Epigenetic mechanisms of gene regulation during mammalian spermatogenesis A M. Khalil, C Wahlestedt Epigenetics 3 (1), 21-27, 2008 | 55 | 2008 |
Evolutionarily conserved long intergenic non-coding RNAs in the eye D Mustafi, BM Kevany, X Bai, T Maeda, JE Sears, AM Khalil, K Palczewski Human molecular genetics 22 (15), 2992-3002, 2013 | 46 | 2013 |
Colon Cancer-Upregulated Long Non-Coding RNA lincDUSP Regulates Cell Cycle Genes and Potentiates Resistance to Apoptosis ME Forrest, A Saiakhova, L Beard, DA Buchner, PC Scacheri, ... Scientific reports 8 (1), 7324, 2018 | 38 | 2018 |
Transcriptome-Wide Analyses of Human Neonatal Articular Cartilage and Human Mesenchymal Stem Cell-Derived Cartilage Provide a New Molecular Target for Evaluating Engineered … RA Somoza, D Correa, I Labat, H Sternberg, ME Forrest, AM Khalil, ... Tissue Engineering Part A 24 (3-4), 335-350, 2018 | 37 | 2018 |