Organofluorine chemistry: Promising growth areas and challenges LV Politanskaya, GA Selivanova, EV Panteleeva, EV Tretyakov, ... Russian Chemical Reviews 88 (5), 425, 2019 | 159 | 2019 |
Conjugates of γ-Carbolines and Phenothiazine as new selective inhibitors of butyrylcholinesterase and blockers of NMDA receptors for Alzheimer Disease GF Makhaeva, SV Lushchekina, NP Boltneva, VB Sokolov, VV Grigoriev, ... Scientific reports 5 (1), 13164, 2015 | 105 | 2015 |
Organophosphorus compound esterase profiles as predictors of therapeutic and toxic effects GF Makhaeva, EV Radchenko, VA Palyulin, EV Rudakova, AY Aksinenko, ... Chemico-biological interactions 203 (1), 231-237, 2013 | 83 | 2013 |
Chronic administration of dimebon ameliorates pathology in Tau P301S transgenic mice OM Peters, N Connor-Robson, VB Sokolov, AY Aksinenko, MS Kukharsky, ... Journal of Alzheimer's disease 33 (4), 1041-1049, 2013 | 79 | 2013 |
Novel conjugates of aminoadamantanes with carbazole derivatives as potential multitarget agents for AD treatment SO Bachurin, EF Shevtsova, GF Makhaeva, VV Grigoriev, NP Boltneva, ... Scientific Reports 7 (1), 45627, 2017 | 78 | 2017 |
Synthesis of organophosphates with fluorine-containing leaving groups as serine esterase inhibitors with potential for Alzheimer disease therapeutics GF Makhaeva, AY Aksinenko, VB Sokolov, OG Serebryakova, ... Bioorganic & Medicinal Chemistry Letters 19 (19), 5528-5530, 2009 | 58 | 2009 |
Esterase profiles of organophosphorus compounds in vitro predict their behavior in vivo GF Makhaeva, EV Rudakova, OG Serebryakova, AY Aksinenko, ... Chemico-Biological Interactions 259, 332-342, 2016 | 44 | 2016 |
Esterase profile and analysis of structure-inhibitor selectivity relationships for homologous phosphorylated 1-hydroperfluoroisopropanols GF Makhaeva, OG Serebryakova, NP Boltneva, TG Galenko, ... Doklady. Biochemistry and Biophysics 423 (1), 352, 2008 | 41 | 2008 |
Focused design of polypharmacophoric neuroprotective compounds: Conjugates of γ-carbolines with carbazole derivatives and tetrahydrocarbazole GF Makhaeva, VB Sokolov, EF Shevtsova, NV Kovaleva, SV Lushchekina, ... Pure and Applied Chemistry 89 (8), 1167-1184, 2017 | 40 | 2017 |
Kinetics and mechanism of inhibition of serine esterases by fluorinated aminophosphonates GF Makhaeva, AY Aksinenko, VB Sokolov, II Baskin, VA Palyulin, ... Chemico-biological interactions 187 (1-3), 177-184, 2010 | 36 | 2010 |
Fluorinated α-aminophosphonates—a new type of irreversible inhibitors of serine hydrolases GF Makhaeva, VV Malygin, AY Aksinenko, VB Sokolov, NN Strakhova, ... Doklady Biochemistry and Biophysics 400, 92-95, 2005 | 33 | 2005 |
Pro-neurogenic, memory-enhancing and anti-stress effects of DF302, a novel fluorine gamma-carboline derivative with multi-target mechanism of action T Strekalova, N Bahzenova, A Trofimov, AG Schmitt-Böhrer, N Markova, ... Molecular neurobiology 55, 335-349, 2018 | 32 | 2018 |
Conjugates of methylene blue with γ-carboline derivatives as new multifunctional agents for the treatment of neurodegenerative diseases SO Bachurin, GF Makhaeva, EF Shevtsova, NP Boltneva, NV Kovaleva, ... Scientific reports 9 (1), 4873, 2019 | 29 | 2019 |
Targeted synthesis and biological activity of polypharmacophoric agents for the treatment of neurodegenerative diseases VB Sokolov, GF Makhaeva, AY Aksinenko, VV Grigoriev, EF Shevtsova, ... Russian Chemical Bulletin 66, 1821-1831, 2017 | 21 | 2017 |
Synthesis of bis (trifluoromethyl) pyrimido [4, 5-d] pyrimidine-2, 4-diones and evaluation of their antibacterial and antifungal activities AY Aksinenko, TV Goreva, TA Epishina, SV Trepalin, VB Sokolov Journal of Fluorine Chemistry 188, 191-195, 2016 | 21 | 2016 |
Synthesis of 3-fluoro-2-(diethoxyphosphoryl) imidazo [1, 2-a] pyridine AY Aksinenko, TV Goreva, TA Epishina, VB Sokolov Journal of Fluorine Chemistry 137, 105-107, 2012 | 19 | 2012 |
Molecular design of multitarget neuroprotectors 3. Synthesis and bioactivity of tetrahydrocarbazole—aminoadamantane conjugates VB Sokolov, AY Aksinenko, TV Goreva, TA Epishina, VV Grigor´ ev, ... Russian Chemical Bulletin 65, 1354-1359, 2016 | 18 | 2016 |
Molecular design of multitarget neuroprotectors 2. Synthesis and bioactivity of carbazole—γ-carboline conjugates VB Sokolov, AY Aksinenko, TV Goreva, TA Epishina, VV Grigor´ ev, ... Russian Chemical Bulletin 65, 1346-1353, 2016 | 18 | 2016 |
Arenesulfonylimines of methyl trifluoropyruvate in the cyclocondensation reactions with 1, 3-C, N-and-N, N-binucleophiles VB Sokolov, AY Aksinenko, IV Martynov Russian Chemical Bulletin 56 (11), 2247-2251, 2007 | 18 | 2007 |
Intramolecular cyclization of 1-allyl-and 1-methallyl-6-amino-2-thiouracils VB Sokolov, AY Aksinenko, AN Pushin, IV Martynov Russian chemical bulletin 54, 1744-1746, 2005 | 18 | 2005 |