David C Wedge
David C Wedge
Professor of Cancer Genomics and Data Science, University of Manchester
Verified email at manchester.ac.uk - Homepage
Title
Cited by
Cited by
Year
Signatures of mutational processes in human cancer
LB Alexandrov, S Nik-Zainal, DC Wedge, SAJR Aparicio, S Behjati, ...
Nature 500 (7463), 415-421, 2013
62532013
Somatic CALR Mutations in Myeloproliferative Neoplasms with Nonmutated JAK2
J Nangalia, CE Massie, EJ Baxter, FL Nice, G Gundem, DC Wedge, ...
New England Journal of Medicine 369 (25), 2391-2405, 2013
15982013
The landscape of cancer genes and mutational processes in breast cancer
PJ Stephens, PS Tarpey, H Davies, P Van Loo, C Greenman, DC Wedge, ...
Nature 486 (7403), 400-404, 2012
15832012
Mutational processes molding the genomes of 21 breast cancers
S Nik-Zainal, LB Alexandrov, DC Wedge, P Van Loo, CD Greenman, ...
Cell 149 (5), 979-993, 2012
14562012
Clinical and biological implications of driver mutations in myelodysplastic syndromes
E Papaemmanuil, M Gerstung, L Malcovati, S Tauro, G Gundem, ...
Blood 122 (22), 3616-3627, 2013
13182013
Landscape of somatic mutations in 560 breast cancer whole-genome sequences
S Nik-Zainal, H Davies, J Staaf, M Ramakrishna, D Glodzik, X Zou, ...
Nature 534 (7605), 47-54, 2016
12142016
The life history of 21 breast cancers
S Nik-Zainal, P Van Loo, DC Wedge, LB Alexandrov, CD Greenman, ...
Cell 149 (5), 994-1007, 2012
11862012
High burden and pervasive positive selection of somatic mutations in normal human skin
I Martincorena, A Roshan, M Gerstung, P Ellis, P Van Loo, S McLaren, ...
Science 348 (6237), 880-886, 2015
9732015
The evolutionary history of lethal metastatic prostate cancer
G Gundem, P Van Loo, B Kremeyer, LB Alexandrov, JMC Tubio, ...
Nature 520 (7547), 353-357, 2015
9112015
Spatial and temporal diversity in genomic instability processes defines lung cancer evolution
EC de Bruin, N McGranahan, R Mitter, M Salm, DC Wedge, L Yates, ...
Science 346 (6206), 251-256, 2014
8632014
Deciphering signatures of mutational processes operative in human cancer
LB Alexandrov, S Nik-Zainal, DC Wedge, PJ Campbell, MR Stratton
Cell reports 3 (1), 246-259, 2013
7992013
Intratumor heterogeneity in localized lung adenocarcinomas delineated by multiregion sequencing
J Zhang, J Fujimoto, J Zhang, DC Wedge, X Song, J Zhang, S Seth, ...
Science 346 (6206), 256-259, 2014
7322014
Heterogeneity of genomic evolution and mutational profiles in multiple myeloma
N Bolli, H Avet-Loiseau, DC Wedge, P Van Loo, LB Alexandrov, ...
Nature communications 5 (1), 1-13, 2014
6662014
Subclonal diversification of primary breast cancer revealed by multiregion sequencing
LR Yates, M Gerstung, S Knappskog, C Desmedt, G Gundem, P Van Loo, ...
Nature medicine 21 (7), 751, 2015
5422015
Clock-like mutational processes in human somatic cells
LB Alexandrov, PH Jones, DC Wedge, JE Sale, PJ Campbell, ...
Nature genetics 47 (12), 1402, 2015
5292015
Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone
S Behjati, PS Tarpey, N Presneau, S Scheipl, N Pillay, P Van Loo, ...
Nature genetics 45 (12), 1479-1482, 2013
4642013
Effect of mutation order on myeloproliferative neoplasms
CA Ortmann, DG Kent, J Nangalia, Y Silber, DC Wedge, J Grinfeld, ...
New England Journal of Medicine 372 (7), 601-612, 2015
3942015
Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue
CS Cooper, R Eeles, DC Wedge, P Van Loo, G Gundem, LB Alexandrov, ...
Nature genetics 47 (4), 367-372, 2015
3362015
Genomic evolution of breast cancer metastasis and relapse
LR Yates, S Knappskog, D Wedge, JHR Farmery, S Gonzalez, ...
Cancer cell 32 (2), 169-184. e7, 2017
3202017
Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes
JMC Tubio, Y Li, YS Ju, I Martincorena, SL Cooke, M Tojo, G Gundem, ...
Science 345 (6196), 2014
2892014
The system can't perform the operation now. Try again later.
Articles 1–20