Rosa Marina Melillo
Rosa Marina Melillo
Professore del Dipartimento di Medicina Molecolare e Biotecnologie Mediche UNINA
Verified email at
TitleCited byYear
PTC is a novel rearranged form of the ret proto-oncogene and is frequently detected in vivo in human thyroid papillary carcinomas
M Grieco, M Santoro, MT Berlingieri, RM Melillo, R Donghi, I Bongarzone, ...
Cell 60 (4), 557-563, 1990
Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27Kip1 by PKB/Akt-mediated phosphorylation in breast cancer
G Viglietto, ML Motti, P Bruni, RM Melillo, A D'alessio, D Califano, F Vinci, ...
Nature medicine 8 (10), 1136, 2002
Ret oncogene activation in human thyroid neoplasms is restricted to the papillary cancer subtype.
M Santoro, F Carlomagno, ID Hay, MA Herrmann, M Grieco, R Melillo, ...
The Journal of clinical investigation 89 (5), 1517-1522, 1992
The RET/PTC-RAS-BRAF linear signaling cascade mediates the motile and mitogenic phenotype of thyroid cancer cells
RM Melillo, MD Castellone, V Guarino, V De Falco, AM Cirafici, ...
The Journal of clinical investigation 115 (4), 1068-1081, 2005
HMGA2 induces pituitary tumorigenesis by enhancing E2F1 activity
M Fedele, R Visone, I De Martino, G Troncone, D Palmieri, S Battista, ...
Cancer cell 9 (6), 459-471, 2006
RET/PTC activation in papillary thyroid carcinoma: European Journal of Endocrinology Prize Lecture
M Santoro, RM Melillo, A Fusco
European Journal of Endocrinology 155 (5), 645-653, 2006
Minireview: RET: normal and abnormal functions
M Santoro, RM Melillo, F Carlomagno, G Vecchio, A Fusco
Endocrinology 145 (12), 5448-5451, 2004
Molecular mechanisms of RET activation in human cancer
M Santoro, RM Melillo, F Carlomagno, A Fusco, G Vecchio
Annals of the New York Academy of Sciences 963 (1), 116-121, 2002
BRAF is a therapeutic target in aggressive thyroid carcinoma
G Salvatore, V De Falco, P Salerno, TC Nappi, S Pepe, G Troncone, ...
Clinical Cancer Research 12 (5), 1623-1629, 2006
Thyroid cancer and inflammation
V Guarino, MD Castellone, E Avilla, RM Melillo
Molecular and cellular Endocrinology 321 (1), 94-102, 2010
Functional expression of the CXCR4 chemokine receptor is induced by RET/PTC oncogenes and is a common event in human papillary thyroid carcinomas
MD Castellone, V Guarino, V De Falco, F Carlomagno, F Basolo, ...
Oncogene 23 (35), 5958, 2004
A cell proliferation and chromosomal instability signature in anaplastic thyroid carcinoma
G Salvatore, TC Nappi, P Salerno, Y Jiang, C Garbi, C Ugolini, P Miccoli, ...
Cancer research 67 (21), 10148-10158, 2007
Docking protein FRS2 links the protein tyrosine kinase RET and its oncogenic forms with the mitogen-activated protein kinase signaling cascade
RM Melillo, M Santoro, SH Ong, M Billaud, A Fusco, YR Hadari, ...
Molecular and Cellular Biology 21 (13), 4177-4187, 2001
The TRK and RET tyrosine kinase oncogenes cooperate with ras in the neoplastic transformation of a rat thyroid epithelial cell line
M Santoro, RM Melillo, M Grieco, MT Berlingieri, G Vecchio, A Fusco
Cell Growth and Differentiation 4, 77-77, 1993
Signalling of the Ret receptor tyrosine kinase through the c-Jun NH2-terminal protein kinases (JNKs): evidence for a divergence of the ERKs and JNKs pathways …
M Chiariello, R Visconti, F Carlomagno, RM Melillo, C Bucci, ...
Oncogene 16 (19), 2435, 1998
Molecular heterogeneity of RET loss of function in Hirschsprung's disease.
F Carlomagno, G De Vita, MT Berlingieri, V De Franciscis, RM Melillo, ...
The EMBO Journal 15 (11), 2717-2725, 1996
Efficient Inhibition of RET/Papillary Thyroid Carcinoma Oncogenic Kinases by 4-Amino-5-(4-Chloro-Phenyl)-7-(t-Butyl)Pyrazolo[3,4-d]Pyrimidine (PP2)
F Carlomagno, D Vitagliano, T Guida, F Basolo, MD Castellone, ...
The Journal of Clinical Endocrinology & Metabolism 88 (4), 1897-1902, 2003
Mast cells have a protumorigenic role in human thyroid cancer
RM Melillo, V Guarino, E Avilla, MR Galdiero, F Liotti, N Prevete, ...
Oncogene 29 (47), 6203, 2010
Biological role and potential therapeutic targeting of the chemokine receptor CXCR4 in undifferentiated thyroid cancer
V De Falco, V Guarino, E Avilla, MD Castellone, P Salerno, G Salvatore, ...
Cancer research 67 (24), 11821-11829, 2007
Potent mitogenicity of the RET/PTC3 oncogene correlates with its prevalence in tall-cell variant of papillary thyroid carcinoma
F Basolo, R Giannini, C Monaco, RM Melillo, F Carlomagno, M Pancrazi, ...
The American journal of pathology 160 (1), 247-254, 2002
The system can't perform the operation now. Try again later.
Articles 1–20