| CD4 T cell depletion is linked directly to immune activation in the pathogenesis of HIV-1 and HIV-2 but only indirectly to the viral load AE Sousa, J Carneiro, M Meier-Schellersheim, Z Grossman, ... The Journal of Immunology 169 (6), 3400-3406, 2002 | 664 | 2002 |
| CD4+ T-cell depletion in HIV infection: Are we closer to understanding the cause? Z Grossman, M Meier-Schellersheim, AE Sousa, RMM Victorino, WE Paul Nature medicine 8 (4), 319-323, 2002 | 609 | 2002 |
| Positive epistasis drives the acquisition of multidrug resistance S Trindade, A Sousa, KB Xavier, F Dionisio, MG Ferreira, I Gordo PLoS genetics 5 (7), e1000578, 2009 | 286 | 2009 |
| Immunochip analysis identifies multiple susceptibility loci for systemic sclerosis MD Mayes, L Bossini-Castillo, O Gorlova, JE Martin, X Zhou, WV Chen, ... The American Journal of Human Genetics 94 (1), 47-61, 2014 | 246 | 2014 |
| Age-associated distribution of normal B-cell and plasma cell subsets in peripheral blood E Blanco, M Pérez-Andrés, S Arriba-Méndez, T Contreras-Sanfeliciano, ... Journal of Allergy and Clinical Immunology 141 (6), 2208-2219. e16, 2018 | 227 | 2018 |
| Acute effects of Benzo [a] pyrene, anthracene and a fuel oil on biomarkers of the common goby Pomatoschistus microps (Teleostei, Gobiidae) LR Vieira, A Sousa, MF Frasco, I Lima, F Morgado, L Guilhermino Science of the total environment 395 (2-3), 87-100, 2008 | 183 | 2008 |
| The First Steps of Adaptation of Escherichia coli to the Gut Are Dominated by Soft Sweeps J Barroso-Batista, A Sousa, M Lourenço, ML Bergman, D Sobral, ... PLoS genetics 10 (3), e1004182, 2014 | 181 | 2014 |
| Platelets are necessary for airway wall remodeling in a murine model of chronic allergic inflammation SC Pitchford, Y Riffo-Vasquez, A Sousa, S Momi, P Gresele, D Spina, ... Blood 103 (2), 639-647, 2004 | 176 | 2004 |
| Factors influencing the physical characteristics of pellets obtained by extrusion-spheronization JJ Sousa, A Sousa, F Podczeck, JM Newton International Journal of Pharmaceutics 232 (1-2), 91-106, 2002 | 145 | 2002 |
| Human blood Tfr cells are indicators of ongoing humoral activity not fully licensed with suppressive function VR Fonseca, A Agua-Doce, AR Maceiras, W Pierson, F Ribeiro, ... Science Immunology 2 (14), eaan1487, 2017 | 140 | 2017 |
| Treatment with tocilizumab or corticosteroids for COVID-19 patients with hyperinflammatory state: a multicentre cohort study (SAM-COVID-19) J Rodríguez-Baño, J Pachón, J Carratala, P Ryan, I Jarrín, M Yllescas, ... Clinical Microbiology and Infection 27 (2), 244-252, 2021 | 137 | 2021 |
| Horizontal gene transfer overrides mutation in Escherichia coli colonizing the mammalian gut N Frazão, A Sousa, M Lässig, I Gordo Proceedings of the National Academy of Sciences 116 (36), 17906-17915, 2019 | 134 | 2019 |
| Regulatory T-cell development in the human thymus Í Caramalho, H Nunes-Cabaço, RB Foxall, AE Sousa Frontiers in immunology 6, 156815, 2015 | 125 | 2015 |
| Human γδ thymocytes are functionally immature and differentiate into cytotoxic type 1 effector T cells upon IL-2/IL-15 signaling JC Ribot, ST Ribeiro, DV Correia, AE Sousa, B Silva-Santos The Journal of Immunology 192 (5), 2237-2243, 2014 | 123 | 2014 |
| First use of thymus transplantation therapy for FOXN1 deficiency (nude/SCID): a report of 2 cases ML Markert, JG Marques, B Neven, BH Devlin, EA McCarthy, IK Chinn, ... Blood, The Journal of the American Society of Hematology 117 (2), 688-696, 2011 | 119 | 2011 |
| Recent thymic emigrants are the preferential precursors of regulatory T cells differentiated in the periphery RS Paiva, AC Lino, ML Bergman, Í Caramalho, AE Sousa, S Zelenay, ... Proceedings of the National Academy of Sciences 110 (16), 6494-6499, 2013 | 101 | 2013 |
| Rates of fitness decline and rebound suggest pervasive epistasis L Perfeito, A Sousa, T Bataillon, I Gordo Evolution 68 (1), 150-162, 2014 | 99 | 2014 |
| Expansion of circulating Foxp3+CD25bright CD4+ T cells during specific venom immunotherapy MC Pereira‐Santos, AP Baptista, A Melo, RR Alves, RS Soares, E Pedro, ... Clinical & Experimental Allergy 38 (2), 291-297, 2008 | 99 | 2008 |
| IL-7 sustains CD31 expression in human naive CD4+ T cells and preferentially expands the CD31+ subset in a PI3K-dependent manner RI Azevedo, MVD Soares, JT Barata, R Tendeiro, A Serra-Caetano, ... Blood, The Journal of the American Society of Hematology 113 (13), 2999-3007, 2009 | 97 | 2009 |
| Cost of antibiotic resistance and the geometry of adaptation A Sousa, S Magalhaes, I Gordo Molecular biology and evolution 29 (5), 1417-1428, 2012 | 94 | 2012 |
