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Charles Imbusch
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Year
Pan-cancer analysis of whole genomes
Nature 578 (7793), 82-93, 2020
1680*2020
The whole-genome landscape of medulloblastoma subtypes
PA Northcott, I Buchhalter, AS Morrissy, V Hovestadt, J Weischenfeldt, ...
Nature 547 (7663), 311-317, 2017
9572017
Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma
DTW Jones, B Hutter, N Jäger, A Korshunov, M Kool, HJ Warnatz, ...
Nature genetics 45 (8), 927-932, 2013
7952013
Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma
PA Northcott, C Lee, T Zichner, AM Stütz, S Erkek, D Kawauchi, DJH Shih, ...
Nature 511 (7510), 428-434, 2014
6702014
DNA methylation dynamics during B cell maturation underlie a continuum of disease phenotypes in chronic lymphocytic leukemia
CC Oakes, M Seifert, Y Assenov, L Gu, M Przekopowitz, AS Ruppert, ...
Nature genetics 48 (3), 253-264, 2016
3202016
DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats
D Brocks, CR Schmidt, M Daskalakis, HS Jang, NM Shah, D Li, J Li, ...
Nature genetics 49 (7), 1052-1060, 2017
2752017
Genome-wide DNA-methylation landscape defines specialization of regulatory T cells in tissues
M Delacher, CD Imbusch, D Weichenhan, A Breiling, A Hotz-Wagenblatt, ...
Nature immunology 18 (10), 1160-1172, 2017
2242017
Epigenomic profiling of human CD4+ T cells supports a linear differentiation model and highlights molecular regulators of memory development
P Durek, K Nordström, G Gasparoni, A Salhab, C Kressler, M De Almeida, ...
Immunity 45 (5), 1148-1161, 2016
1962016
Precursors for nonlymphoid-tissue Treg cells reside in secondary lymphoid organs and are programmed by the transcription factor BATF
M Delacher, CD Imbusch, A Hotz-Wagenblatt, JP Mallm, K Bauer, ...
Immunity 52 (2), 295-312. e11, 2020
1612020
Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells
M Delacher, M Simon, L Sanderink, A Hotz-Wagenblatt, M Wuttke, ...
Immunity 54 (4), 702-720. e17, 2021
902021
Aggressive PDACs show hypomethylation of repetitive elements and the execution of an intrinsic IFN program linked to a ductal cell of origin
E Espinet, Z Gu, CD Imbusch, NA Giese, M Büscher, M Safavi, ...
Cancer discovery 11 (3), 638-659, 2021
792021
Rbpj expression in regulatory T cells is critical for restraining TH2 responses
M Delacher, C Schmidl, Y Herzig, M Breloer, W Hartmann, F Brunk, ...
Nature communications 10 (1), 1621, 2019
372019
Integrative analysis of single-cell expression data reveals distinct regulatory states in bidirectional promoters
F Behjati Ardakani, K Kattler, K Nordström, N Gasparoni, G Gasparoni, ...
Epigenetics & chromatin 11, 1-14, 2018
112018
Lorlatinib induces durable disease stabilization in a pancreatic cancer patient with a ROS1 p. L1950F mutation: case report
JL Velthaus, P Iglauer, R Simon, C Bokemeyer, P Bannas, N Beumer, ...
Oncology Research and Treatment 44 (9), 495-502, 2021
92021
Quantitative proteomics identifies TCF1 as a negative regulator of Foxp3 expression in conventional T cells
M Delacher, MM Barra, Y Herzig, K Eichelbaum, MR Rafiee, DM Richards, ...
Iscience 23 (5), 2020
72020
Spatially resolved multi-omics single-cell analyses inform mechanisms of immune dysfunction in pancreatic cancer
S Yousuf, M Qiu, LV von Voithenberg, J Hulkkonen, I Macinkovic, ...
Gastroenterology 165 (4), 891-908. e14, 2023
62023
Integrated single-cell profiling dissects cell-state-specific enhancer landscapes of human tumor-infiltrating CD8+ T cells
D Riegel, E Romero-Fernández, M Simon, AR Adenugba, K Singer, ...
Molecular Cell 83 (4), 622-636. e10, 2023
62023
Deconvolution of sarcoma methylomes reveals varying degrees of immune cell infiltrates with association to genomic aberrations
M Simon, SS Mughal, P Horak, S Uhrig, J Buchloh, B Aybey, A Stenzinger, ...
Journal of translational medicine 19 (1), 204, 2021
62021
Corrigendum: Genome-wide DNA-methylation landscape defines specialization of regulatory T cells in tissues
M Delacher, CD Imbusch, D Weichenhan, A Breiling, A Hotz-Wagenblatt, ...
Nature immunology 18 (12), 1361, 2017
62017
Pathologic responses in oligometastatic NSCLC patients treated with neoadjuvant immune checkpoint blockade with and without chemotherapy followed by surgery
T Boch, N Frost, L Sommer, TR Overbeck, CT Michaeli, CJ Szuszies, ...
Lung Cancer 164, 46-51, 2022
42022
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