| Activin A directs striatal projection neuron differentiation of human pluripotent stem cells C Arber, SV Precious, S Cambray, JR Risner-Janiczek, C Kelly, Z Noakes, ... Development 142 (7), 1375-1386, 2015 | 182 | 2015 |
| Developmental regulation of tau splicing is disrupted in stem cell-derived neurons from frontotemporal dementia patients with the 10+ 16 splice-site mutation in MAPT T Sposito, E Preza, CJ Mahoney, N Setó-Salvia, NS Ryan, HR Morris, ... Human molecular genetics 24 (18), 5260-5269, 2015 | 164 | 2015 |
| Stem cell models of Alzheimer’s disease: progress and challenges C Arber, C Lovejoy, S Wray Alzheimer's research & therapy 9, 1-17, 2017 | 159 | 2017 |
| Human induced pluripotent stem cell-derived microglia-like cells harboring TREM2 missense mutations show specific deficits in phagocytosis P Garcia-Reitboeck, A Phillips, TM Piers, C Villegas-Llerena, M Butler, ... Cell Reports 24 (9), 2300-2311, 2018 | 141 | 2018 |
| Familial Alzheimer’s disease patient-derived neurons reveal distinct mutation-specific effects on amyloid beta C Arber, J Toombs, C Lovejoy, NS Ryan, RW Paterson, N Willumsen, ... Molecular Psychiatry 25 (11), 2919-2931, 2020 | 127 | 2020 |
| Insights into molecular mechanisms of disease in neurodegeneration with brain iron accumulation: unifying theories CE Arber, A Li, H Houlden, S Wray Neuropathology and applied neurobiology 42 (3), 220-241, 2016 | 125 | 2016 |
| Temporally controlled modulation of FGF/ERK signaling directs midbrain dopaminergic neural progenitor fate in mouse and human pluripotent stem cells I Jaeger, C Arber, JR Risner-Janiczek, J Kuechler, D Pritzsche, IC Chen, ... Development 138 (20), 4363-4374, 2011 | 114 | 2011 |
| Activin induces cortical interneuron identity and differentiation in embryonic stem cell-derived telencephalic neural precursors S Cambray, C Arber, G Little, AG Dougalis, V De Paola, MA Ungless, M Li, ... Nature communications 3 (1), 841, 2012 | 80 | 2012 |
| Familial Alzheimer’s disease mutations in PSEN1 lead to premature human stem cell neurogenesis C Arber, C Lovejoy, L Harris, N Willumsen, A Alatza, JM Casey, G Lines, ... Cell reports 34 (2), 2021 | 66 | 2021 |
| Susceptibility of brain atrophy to TRIB3 in Alzheimer’s disease, evidence from functional prioritization in imaging genetics M Lorenzi, A Altmann, B Gutman, S Wray, C Arber, DP Hibar, ... Proceedings of the National Academy of Sciences 115 (12), 3162-3167, 2018 | 57 | 2018 |
| iPSC-derived neuronal models of PANK2-associated neurodegeneration reveal mitochondrial dysfunction contributing to early disease C Arber, PR Angelova, S Wiethoff, Y Tsuchiya, F Mazzacuva, E Preza, ... PloS one 12 (9), e0184104, 2017 | 44 | 2017 |
| Cortical interneurons from human pluripotent stem cells: prospects for neurological and psychiatric disease C Arber, M Li Frontiers in cellular neuroscience 7, 10, 2013 | 39 | 2013 |
| Mutations in valosin-containing protein (VCP) decrease ADP/ATP translocation across the mitochondrial membrane and impair energy metabolism in human neurons MHR Ludtmann, C Arber, F Bartolome, M de Vicente, E Preza, E Carro, ... Journal of Biological Chemistry 292 (21), 8907-8917, 2017 | 37 | 2017 |
| Analysis of macroautophagy related proteins in G2019S LRRK2 Parkinson’s disease brains with Lewy body pathology A Mamais, C Manzoni, I Nazish, C Arber, B Sonustun, S Wray, TT Warner, ... Brain research 1701, 75-84, 2018 | 35 | 2018 |
| Amyloid β peptides are differentially vulnerable to preanalytical surface exposure, an effect incompletely mitigated by the use of ratios J Toombs, MS Foiani, H Wellington, RW Paterson, C Arber, A Heslegrave, ... Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring 10, 311-321, 2018 | 29 | 2018 |
| Abrogation of LRRK2 dependent Rab10 phosphorylation with TLR4 activation and alterations in evoked cytokine release in immune cells I Nazish, C Arber, TM Piers, TT Warner, JA Hardy, PA Lewis, JM Pocock, ... Neurochemistry international 147, 105070, 2021 | 19 | 2021 |
| Amyloid precursor protein processing in human neurons with an allelic series of the PSEN1 intron 4 deletion mutation and total presenilin-1 knockout C Arber, C Villegas-Llerena, J Toombs, JM Pocock, NS Ryan, NC Fox, ... Brain communications 1 (1), fcz024, 2019 | 18 | 2019 |
| Plasma amyloid-β ratios in autosomal dominant Alzheimer’s disease: the influence of genotype A O'Connor, J Pannee, T Poole, C Arber, E Portelius, IJ Swift, ... Brain 144 (10), 2964-2970, 2021 | 17 | 2021 |
| Using human induced pluripotent stem cells to model cerebellar disease: hope and hype S Wiethoff, C Arber, A Li, S Wray, H Houlden, R Patani Journal of neurogenetics 29 (2-3), 95-102, 2015 | 12 | 2015 |
| Knockdown of amyloid precursor protein: biological consequences and clinical opportunities RMC Gabriele, E Abel, NC Fox, S Wray, C Arber Frontiers in Neuroscience 16, 835645, 2022 | 11 | 2022 |
