Experimental investigation of geologically produced antineutrinos with KamLAND T Araki, S Enomoto, K Furuno, Y Gando, K Ichimura, H Ikeda, K Inoue, ... Nature 436 (7050), 499-503, 2005 | 584 | 2005 |
Genomic analysis of oesophageal squamous-cell carcinoma identifies alcohol drinking-related mutation signature and genomic alterations J Chang, W Tan, Z Ling, R Xi, M Shao, M Chen, Y Luo, Y Zhao, Y Liu, ... Nature communications 8 (1), 15290, 2017 | 213 | 2017 |
m6A mRNA methylation regulates human β-cell biology in physiological states and in type 2 diabetes DF De Jesus, Z Zhang, S Kahraman, NK Brown, M Chen, J Hu, MK Gupta, ... Nature Metabolism 1 (8), 765-774, 2019 | 204 | 2019 |
Tdrkh is essential for spermatogenesis and participates in primary piRNA biogenesis in the germline JP Saxe, M Chen, H Zhao, H Lin The EMBO journal 32 (13), 1869-1885, 2013 | 200 | 2013 |
Robust covariance and scatter matrix estimation under Huber’s contamination model M Chen, C Gao, Z Ren The Annals of Statistics 46 (5), 1932-1960, 2018 | 194 | 2018 |
m6A RNA modifications are measured at single-base resolution across the mammalian transcriptome L Hu, S Liu, Y Peng, R Ge, R Su, C Senevirathne, BT Harada, Q Dai, ... Nature biotechnology 40 (8), 1210-1219, 2022 | 191 | 2022 |
Integrated RNA and DNA sequencing reveals early drivers of metastatic breast cancer MB Siegel, X He, KA Hoadley, A Hoyle, JB Pearce, AL Garrett, S Kumar, ... The Journal of clinical investigation 128 (4), 1371-1383, 2018 | 166 | 2018 |
Exon architecture controls mRNA m6A suppression and gene expression PC He, J Wei, X Dou, BT Harada, Z Zhang, R Ge, C Liu, LS Zhang, X Yu, ... Science 379 (6633), 677-682, 2023 | 135 | 2023 |
VIPER: variability-preserving imputation for accurate gene expression recovery in single-cell RNA sequencing studies M Chen, X Zhou Genome biology 19 (1), 196, 2018 | 127 | 2018 |
An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge CA Brownstein, AH Beggs, N Homer, B Merriman, TW Yu, KC Flannery, ... Genome biology 15, 1-18, 2014 | 126 | 2014 |
Intratumoral heterogeneity as a source of discordance in breast cancer biomarker classification EH Allott, J Geradts, X Sun, SM Cohen, GR Zirpoli, T Khoury, W Bshara, ... Breast Cancer Research 18, 1-11, 2016 | 115 | 2016 |
Demystifying “drop-outs” in single-cell UMI data TH Kim, X Zhou, M Chen Genome biology 21 (1), 196, 2020 | 112 | 2020 |
Transcriptome-wide profiling and quantification of N6-methyladenosine by enzyme-assisted adenosine deamination YL Xiao, S Liu, R Ge, Y Wu, C He, M Chen, W Tang Nature biotechnology 41 (7), 993-1003, 2023 | 109 | 2023 |
A general decision theory for Huber’s -contamination model M Chen, C Gao, Z Ren | 106 | 2016 |
Novel HBsAg markers tightly correlate with occult HBV infection and strongly affect HBsAg detection V Svicher, V Cento, M Bernassola, M Neumann-Fraune, F Van Hemert, ... Antiviral research 93 (1), 86-93, 2012 | 98 | 2012 |
Allele-specific open chromatin in human iPSC neurons elucidates functional disease variants S Zhang, H Zhang, Y Zhou, M Qiao, S Zhao, A Kozlova, J Shi, AR Sanders, ... Science 369 (6503), 561-565, 2020 | 94 | 2020 |
Comprehensive analysis of The Cancer Genome Atlas reveals a unique gene and non-coding RNA signature of fibrolamellar carcinoma TA Dinh, ECM Vitucci, E Wauthier, RP Graham, WA Pitman, T Oikawa, ... Scientific reports 7 (1), 44653, 2017 | 91 | 2017 |
Extensive pleiotropism and allelic heterogeneity mediate metabolic effects of IRX3 and IRX5 DR Sobreira, AC Joslin, Q Zhang, I Williamson, GT Hansen, KM Farris, ... Science 372 (6546), 1085-1091, 2021 | 90 | 2021 |
REPIC: a database for exploring the N6-methyladenosine methylome S Liu, A Zhu, C He, M Chen Genome biology 21, 1-13, 2020 | 85 | 2020 |
Integrative differential expression and gene set enrichment analysis using summary statistics for scRNA-seq studies Y Ma, S Sun, X Shang, ET Keller, M Chen, X Zhou Nature communications 11 (1), 1585, 2020 | 78 | 2020 |