Phillip Hawkins
Phillip Hawkins
Group Leader, Babraham Institute
Verified email at - Homepage
Cited by
Cited by
Dual role of phosphatidylinositol-3, 4, 5-trisphosphate in the activation of protein kinase B
D Stokoe, LR Stephens, T Copeland, PRJ Gaffney, CB Reese, GF Painter, ...
Science 277 (5325), 567-570, 1997
Protein kinase B kinases that mediate phosphatidylinositol 3, 4, 5-trisphosphate-dependent activation of protein kinase B
L Stephens, K Anderson, D Stokoe, H Erdjument-Bromage, GF Painter, ...
Science 279 (5351), 710-714, 1998
PI3K signalling: the path to discovery and understanding
B Vanhaesebroeck, L Stephens, P Hawkins
Nature reviews Molecular cell biology 13 (3), 195-203, 2012
A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein βγ subunits
L Stephens, A Smrcka, FT Cooke, TR Jackson, PC Sternweis, PT Hawkins
Cell 77 (1), 83-93, 1994
Crystal structure and functional analysis of Ras binding to its effector phosphoinositide 3-kinase γ
ME Pacold, S Suire, O Perisic, S Lara-Gonzalez, CT Davis, EH Walker, ...
Cell 103 (6), 931-944, 2000
The Gβγ sensitivity of a PI3K is dependent upon a tightly associated adaptor, p101
LR Stephens, A Eguinoa, H Erdjument-Bromage, M Lui, F Cooke, ...
Cell 89 (1), 105-114, 1997
PDGF stimulates an increase in GTP–Rac via activation of phosphoinositide 3-kinase
PT Hawkins, A Eguinoa, RG Qiu, D Stokoe, FT Cooke, R Walters, ...
Current Biology 5 (4), 393-403, 1995
Signalling through Class I PI3Ks in mammalian cells
PT Hawkins, KE Anderson, K Davidson, LR Stephens
Biochemical Society Transactions 34 (5), 647-662, 2006
Rapid breakdown of phosphatidylinositol 4-phosphate and phosphatidylinositol 4, 5-bisphosphate in rat hepatocytes stimulated by vasopressin and other Ca2+-mobilizing hormones
JA Creba, CP Downes, PT Hawkins, G Brewster, RH Michell, CJ Kirk
Biochemical Journal 212 (3), 733-747, 1983
P-Rex1, a PtdIns (3, 4, 5) P3-and Gβγ-regulated guanine-nucleotide exchange factor for Rac
HCE Welch, WJ Coadwell, CD Ellson, GJ Ferguson, SR Andrews, ...
Cell 108 (6), 809-821, 2002
Agonist-stimulated synthesis of phosphatidylinositol (3, 4, 5)-trisphosphate: a new intracellular signalling system?
LR Stephens, TR Jackson, PT Hawkins
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1179 (1), 27-75, 1993
Activation of the small GTP-binding proteins rho and rac by growth factor receptors
CD Nobes, P Hawkins, L Stephens, A Hall
Journal of cell science 108 (1), 225-233, 1995
Activation of phosphoinositide 3-kinase is required for PDGF-stimulated membrane ruffling
S Wennström, P Hawkins, F Cooke, K Hara, K Yonezawa, M Kasuga, ...
Current Biology 4 (5), 385-393, 1994
Phosphoinositide 3-kinase δ gene mutation predisposes to respiratory infection and airway damage
I Angulo, O Vadas, F Garçon, E Banham-Hall, V Plagnol, TR Leahy, ...
Science 342 (6160), 866-871, 2013
Translocation of PDK-1 to the plasma membrane is important in allowing PDK-1 to activate protein kinase B
KE Anderson, J Coadwell, LR Stephens, PT Hawkins
Current Biology 8 (12), 684-691, 1998
PtdIns(3)P regulates the neutrophil oxidase complex by binding to the PX domain of p40(phox).
SLR Ellson CD, Gobert-Gosse S, Anderson KE, Davidson K, Erdjument-Bromage H ...
nature cell biology 3 (7), 679-82, 2001
Phosphoinositide 3-kinase-dependent activation of Rac
HCE Welch, WJ Coadwell, LR Stephens, PT Hawkins
FEBS letters 546 (1), 93-97, 2003
PI3K signalling in inflammation
PT Hawkins, LR Stephens
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2015
Sequential activation of class IB and class IA PI3K is important for the primed respiratory burst of human but not murine neutrophils
AM Condliffe, K Davidson, KE Anderson, CD Ellson, T Crabbe, ...
Blood 106 (4), 1432-1440, 2005
Platelet-derived growth factor stimulates synthesis of Ptdlns (3, 4, 5) P3 by activating a Ptdlns (4, 5) P2 3-OH kinase
PT Hawkins, TR Jackson, LR Stephens
Nature 358 (6382), 157-159, 1992
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