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Jan-Henning Klusmann
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Childhood obesity: increased risk for cardiometabolic disease and cancer in adulthood
S Weihrauch-Blüher, P Schwarz, JH Klusmann
Metabolism 92, 147-152, 2019
4602019
lncRNA MIR100HG-derived miR-100 and miR-125b mediate cetuximab resistance via Wnt/β-catenin signaling
Y Lu, X Zhao, Q Liu, C Li, R Graves-Deal, Z Cao, B Singh, JL Franklin, ...
Nature medicine 23 (11), 1331-1341, 2017
3552017
Developmental stage–selective effect of somatically mutated leukemogenic transcription factor GATA1
Z Li, FJ Godinho, JH Klusmann, M Garriga-Canut, C Yu, SH Orkin
Nature genetics 37 (6), 613-619, 2005
3132005
Next-generation personalised medicine for high-risk paediatric cancer patients–The INFORM pilot study
BC Worst, CM van Tilburg, GP Balasubramanian, P Fiesel, R Witt, ...
European journal of cancer 65, 91-101, 2016
3072016
Treatment and prognostic impact of transient leukemia in neonates with Down syndrome
JH Klusmann, U Creutzig, M Zimmermann, M Dworzak, N Jorch, ...
Blood, The Journal of the American Society of Hematology 111 (6), 2991-2998, 2008
2852008
miR-125b-2 is a potential oncomiR on human chromosome 21 in megakaryoblastic leukemia
JH Klusmann, Z Li, K Böhmer, A Maroz, ML Koch, S Emmrich, FJ Godinho, ...
Genes & development 24 (5), 478-490, 2010
2572010
Refined sgRNA efficacy prediction improves large-and small-scale CRISPR–Cas9 applications
M Labuhn, FF Adams, M Ng, S Knoess, A Schambach, EM Charpentier, ...
Nucleic acids research 46 (3), 1375-1385, 2018
2442018
Successes and challenges in the treatment of pediatric acute myeloid leukemia: a retrospective analysis of the AML-BFM trials from 1987 to 2012
M Rasche, M Zimmermann, L Borschel, JP Bourquin, M Dworzak, ...
Leukemia 32 (10), 2167-2177, 2018
1942018
miR-99a/100∼ 125b tricistrons regulate hematopoietic stem and progenitor cell homeostasis by shifting the balance between TGFβ and Wnt signaling
S Emmrich, M Rasche, J Schöning, C Reimer, S Keihani, A Maroz, Y Xie, ...
Genes & development 28 (8), 858-874, 2014
1882014
The non-coding RNA landscape of human hematopoiesis and leukemia
A Schwarzer, S Emmrich, F Schmidt, D Beck, M Ng, C Reimer, FF Adams, ...
Nature communications 8 (1), 1-17, 2017
1562017
LincRNAs MONC and MIR100HG act as oncogenes in acute megakaryoblastic leukemia
S Emmrich, A Streltsov, F Schmidt, VR Thangapandi, D Reinhardt, ...
Molecular cancer 13, 1-12, 2014
1552014
Next‐generation sequencing for minimal residual disease monitoring in acute myeloid leukemia patients with FLT3‐ITD or NPM1 mutations
F Thol, B Kölking, F Damm, K Reinhardt, JH Klusmann, D Reinhardt, ...
Genes, Chromosomes and Cancer 51 (7), 689-695, 2012
1502012
Developmental stage-specific interplay of GATA1 and IGF signaling in fetal megakaryopoiesis and leukemogenesis
JH Klusmann, FJ Godinho, K Heitmann, A Maroz, ML Koch, D Reinhardt, ...
Genes & development 24 (15), 1659-1672, 2010
1422010
Histone deacetylase inhibitors induce apoptosis in myeloid leukemia by suppressing autophagy
MV Stankov, M El Khatib, B Kumar Thakur, K Heitmann, ...
Leukemia 28 (3), 577-588, 2014
1272014
The pediatric precision oncology INFORM registry: clinical outcome and benefit for patients with very high-evidence targets
CM Van Tilburg, E Pfaff, KW Pajtler, KPS Langenberg, P Fiesel, BC Jones, ...
Cancer discovery 11 (11), 2764-2779, 2021
1262021
Analysis of GATA1 mutations in Down syndrome transient myeloproliferative disorder and myeloid leukemia
KA Alford, K Reinhardt, C Garnett, A Norton, K Böhmer, C von Neuhoff, ...
Blood, The Journal of the American Society of Hematology 118 (8), 2222-2238, 2011
1222011
The role of sirtuin 2 activation by nicotinamide phosphoribosyltransferase in the aberrant proliferation and survival of myeloid leukemia cells
L Dan, O Klimenkova, M Klimiankou, JH Klusman, ...
Haematologica 97 (4), 551, 2012
1212012
Mechanisms of progression of myeloid preleukemia to transformed myeloid leukemia in children with Down syndrome
M Labuhn, K Perkins, S Matzk, L Varghese, C Garnett, E Papaemmanuil, ...
Cancer cell 36 (2), 123-138. e10, 2019
1162019
The role of matched sibling donor allogeneic stem cell transplantation in pediatric high-risk acute myeloid leukemia: results from the AML-BFM 98 study
JH Klusmann, D Reinhardt, M Zimmermann, B Kremens, J Vormoor, ...
Haematologica 97 (1), 21, 2012
992012
Lost in translation: pluripotent stem cell‐derived hematopoiesis
M Ackermann, S Liebhaber, JH Klusmann, N Lachmann
EMBO molecular medicine 7 (11), 1388-1402, 2015
962015
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