Systematic identification of trans eQTLs as putative drivers of known disease associations HJ Westra, MJ Peters, T Esko, H Yaghootkar, C Schurmann, J Kettunen, ... Nature genetics 45 (10), 1238-1243, 2013 | 1411 | 2013 |
mTOR-and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity SC Cheng, J Quintin, RA Cramer, KM Shepardson, S Saeed, V Kumar, ... Science 345 (6204), 2014 | 927 | 2014 |
BCG vaccination protects against experimental viral infection in humans through the induction of cytokines associated with trained immunity RJW Arts, SJ Moorlag, B Novakovic, Y Li, SY Wang, M Oosting, V Kumar, ... Cell host & microbe 23 (1), 89-100. e5, 2018 | 421 | 2018 |
The effect of host genetics on the gut microbiome MJ Bonder, A Kurilshikov, EF Tigchelaar, Z Mujagic, F Imhann, AV Vila, ... Nature genetics 48 (11), 1407-1412, 2016 | 388 | 2016 |
Western diet triggers NLRP3-dependent innate immune reprogramming A Christ, P Günther, MAR Lauterbach, P Duewell, D Biswas, K Pelka, ... Cell 172 (1-2), 162-175. e14, 2018 | 326 | 2018 |
Mapping determinants of gene expression plasticity by genetical genomics in C. elegans Y Li, OA Alvarez, EW Gutteling, M Tijsterman, J Fu, JAG Riksen, ... PLoS Genet 2 (12), e222, 2006 | 299 | 2006 |
Disease variants alter transcription factor levels and methylation of their binding sites MJ Bonder, R Luijk, DV Zhernakova, M Moed, P Deelen, M Vermaat, ... Nature genetics 49 (1), 131-138, 2017 | 239 | 2017 |
Metabolic induction of trained immunity through the mevalonate pathway S Bekkering, RJW Arts, B Novakovic, I Kourtzelis, CDCC van der Heijden, ... Cell 172 (1-2), 135-146. e9, 2018 | 232 | 2018 |
Identification of context-dependent expression quantitative trait loci in whole blood DV Zhernakova, P Deelen, M Vermaat, M Van Iterson, M Van Galen, ... Nature genetics 49 (1), 139-145, 2017 | 224 | 2017 |
Genetical genomics: spotlight on QTL hotspots R Breitling, Y Li, BM Tesson, J Fu, C Wu, T Wiltshire, A Gerrits, ... PLoS Genet 4 (10), e1000232, 2008 | 217 | 2008 |
Host and environmental factors influencing individual human cytokine responses R Ter Horst, M Jaeger, SP Smeekens, M Oosting, MA Swertz, Y Li, ... Cell 167 (4), 1111-1124. e13, 2016 | 214 | 2016 |
A novel trilinear decomposition algorithm for second-order linear calibration ZP Chen, HL Wu, JH Jiang, Y Li, RQ Yu Chemometrics and Intelligent Laboratory Systems 52 (1), 75-86, 2000 | 199 | 2000 |
Sequence polymorphisms cause many false cis eQTLs R Alberts, P Terpstra, Y Li, R Breitling, JP Nap, RC Jansen PloS one 2 (7), e622, 2007 | 156 | 2007 |
A functional genomics approach to understand variation in cytokine production in humans Y Li, M Oosting, SP Smeekens, M Jaeger, R Aguirre-Gamboa, KTT Le, ... Cell 167 (4), 1099-1110. e14, 2016 | 134 | 2016 |
Inter-individual variability and genetic influences on cytokine responses to bacteria and fungi Y Li, M Oosting, P Deelen, I Ricaño-Ponce, S Smeekens, M Jaeger, ... Nature medicine 22 (8), 952-960, 2016 | 109 | 2016 |
Expression quantitative trait loci are highly sensitive to cellular differentiation state A Gerrits, Y Li, BM Tesson, LV Bystrykh, E Weersing, A Ausema, B Dontje, ... PLoS Genet 5 (10), e1000692, 2009 | 108 | 2009 |
Severe COVID-19 is marked by a dysregulated myeloid cell compartment J Schulte-Schrepping, N Reusch, D Paclik, K Baßler, S Schlickeiser, ... Cell 182 (6), 1419-1440. e23, 2020 | 107 | 2020 |
DNA methylation in childhood asthma: an epigenome-wide meta-analysis CJ Xu, C Söderhäll, M Bustamante, N Baïz, O Gruzieva, U Gehring, ... The lancet Respiratory medicine 6 (5), 379-388, 2018 | 103 | 2018 |
Expression profiles of long non-coding RNAs located in autoimmune disease-associated regions reveal immune cell-type specificity B Hrdlickova, V Kumar, K Kanduri, DV Zhernakova, S Tripathi, ... Genome medicine 6 (10), 1-14, 2014 | 89 | 2014 |
Cell specific eQTL analysis without sorting cells HJ Westra, D Arends, T Esko, MJ Peters, C Schurmann, K Schramm, ... PLoS genetics 11 (5), e1005223, 2015 | 83 | 2015 |