Robert B Clarke
Robert B Clarke
Professor of Breast Biology, University of Manchester
Verified email at - Homepage
Cited by
Cited by
Patient-derived xenograft models: an emerging platform for translational cancer research
M Hidalgo, F Amant, AV Biankin, E Budinská, AT Byrne, C Caldas, ...
Cancer discovery 4 (9), 998-1013, 2014
Dissociation between steroid receptor expression and cell proliferation in the human breast
RB Clarke, A Howell, CS Potten, E Anderson
Cancer research 57 (22), 4987-4991, 1997
Aberrant activation of notch signaling in human breast cancer
S Stylianou, RB Clarke, K Brennan
Cancer research 66 (3), 1517-1525, 2006
Regulation of breast cancer stem cell activity by signaling through the Notch4 receptor
H Harrison, G Farnie, SJ Howell, RE Rock, S Stylianou, KR Brennan, ...
Cancer research 70 (2), 709-718, 2010
Interrogating open issues in cancer precision medicine with patient-derived xenografts
AT Byrne, DG Alférez, F Amant, D Annibali, J Arribas, AV Biankin, A Bruna, ...
Nature Reviews Cancer 17 (4), 254-268, 2017
Identification of a putative intestinal stem cell and early lineage marker; musashi-1
CS Potten, C Booth, GL Tudor, D Booth, G Brady, P Hurley, G Ashton, ...
Differentiation 71 (1), 28-41, 2003
Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer
SA Eccles, EO Aboagye, S Ali, AS Anderson, J Armes, F Berditchevski, ...
Breast Cancer Research 15 (5), 1-37, 2013
Risk determination and prevention of breast cancer
A Howell, AS Anderson, RB Clarke, SW Duffy, DG Evans, ...
Breast Cancer Research 16 (5), 1-19, 2014
Mammary stem cells and breast cancer—role of Notch signalling
G Farnie, RB Clarke
Stem cell reviews 3, 169-175, 2007
A detailed mammosphere assay protocol for the quantification of breast stem cell activity
FL Shaw, H Harrison, K Spence, MP Ablett, BM Simões, G Farnie, ...
Journal of mammary gland biology and neoplasia 17, 111-117, 2012
Novel cell culture technique for primary ductal carcinoma in situ: role of Notch and epidermal growth factor receptor signaling pathways
G Farnie, RB Clarke, K Spence, N Pinnock, K Brennan, NG Anderson, ...
Journal of the National Cancer Institute 99 (8), 616-627, 2007
A putative human breast stem cell population is enriched for steroid receptor-positive cells
RB Clarke, K Spence, E Anderson, A Howell, H Okano, CS Potten
Developmental biology 277 (2), 443-456, 2005
Estrogen receptor-positive proliferating cells in the normal and precancerous breast
BS Shoker, C Jarvis, RB Clarke, E Anderson, J Hewlett, MPA Davies, ...
The American journal of pathology 155 (6), 1811-1815, 1999
Recent advances reveal IL-8 signaling as a potential key to targeting breast cancer stem cells
JK Singh, BM Simões, SJ Howell, G Farnie, RB Clarke
Breast Cancer Research 15, 1-9, 2013
Origins of breast cancer subtypes and therapeutic implications
AH Sims, A Howell, SJ Howell, RB Clarke
Nature Clinical Practice Oncology 4 (9), 516-525, 2007
The proliferation of normal human breast tissue implanted into athymic nude mice is stimulated by estrogen but not progesterone
IJ Laidlaw, RB Clarke, A Howell, AW Owen, CS Potten, E Anderson
Endocrinology 136 (1), 164-171, 1995
Estrogen responsiveness and control of normal human breast proliferation
E Anderson, RB Clarke, A Howell
Journal of mammary gland biology and neoplasia 3, 23-35, 1998
Targeting CXCR1/2 significantly reduces breast cancer stem cell activity and increases the efficacy of inhibiting HER2 via HER2-dependent and-independent mechanisms
JK Singh, G Farnie, NJ Bundred, BM Simões, A Shergill, G Landberg, ...
Clinical cancer research 19 (3), 643-656, 2013
Patient-derived xenograft (PDX) models in basic and translational breast cancer research
LE Dobrolecki, SD Airhart, DG Alferez, S Aparicio, F Behbod, ...
Cancer and Metastasis Reviews 35, 547-573, 2016
The centrosomal kinase Nek2 displays elevated levels of protein expression in human breast cancer
DG Hayward, RB Clarke, AJ Faragher, MR Pillai, IM Hagan, AM Fry
Cancer research 64 (20), 7370-7376, 2004
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