Robert B Clarke
Robert B Clarke
Professor of Breast Biology, University of Manchester
Verified email at manchester.ac.uk - Homepage
Title
Cited by
Cited by
Year
Patient-derived xenograft models: an emerging platform for translational cancer research
M Hidalgo, F Amant, AV Biankin, E Budinská, AT Byrne, C Caldas, ...
Cancer discovery 4 (9), 998-1013, 2014
8492014
Dissociation between steroid receptor expression and cell proliferation in the human breast
RB Clarke, A Howell, CS Potten, E Anderson
Cancer research 57 (22), 4987-4991, 1997
7591997
Aberrant activation of notch signaling in human breast cancer
S Stylianou, RB Clarke, K Brennan
Cancer research 66 (3), 1517-1525, 2006
5782006
Identification of a putative intestinal stem cell and early lineage marker; musashi‐1
CS Potten, C Booth, GL Tudor, D Booth, G Brady, P Hurley, G Ashton, ...
Differentiation: REVIEW 71 (1), 28-41, 2003
5332003
Regulation of breast cancer stem cell activity by signaling through the Notch4 receptor
H Harrison, G Farnie, SJ Howell, RE Rock, S Stylianou, KR Brennan, ...
Cancer research 70 (2), 709-718, 2010
5222010
Mammary stem cells and breast cancer—role of Notch signalling
G Farnie, RB Clarke
Stem cell reviews 3 (2), 169-175, 2007
4072007
Novel cell culture technique for primary ductal carcinoma in situ: role of Notch and epidermal growth factor receptor signaling pathways
G Farnie, RB Clarke, K Spence, N Pinnock, K Brennan, NG Anderson, ...
Journal of the National Cancer Institute 99 (8), 616-627, 2007
3832007
A putative human breast stem cell population is enriched for steroid receptor-positive cells
RB Clarke, K Spence, E Anderson, A Howell, H Okano, CS Potten
Developmental biology 277 (2), 443-456, 2005
3782005
Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer
SA Eccles, EO Aboagye, S Ali, AS Anderson, J Armes, F Berditchevski, ...
Breast Cancer Research 15 (5), 1-37, 2013
3642013
Estrogen receptor-positive proliferating cells in the normal and precancerous breast
BS Shoker, C Jarvis, RB Clarke, E Anderson, J Hewlett, MPA Davies, ...
The American journal of pathology 155 (6), 1811-1815, 1999
3251999
A detailed mammosphere assay protocol for the quantification of breast stem cell activity
FL Shaw, H Harrison, K Spence, MP Ablett, BM Simões, G Farnie, ...
Journal of mammary gland biology and neoplasia 17 (2), 111-117, 2012
3042012
Interrogating open issues in cancer precision medicine with patient-derived xenografts
AT Byrne, DG Alférez, F Amant, D Annibali, J Arribas, AV Biankin, A Bruna, ...
Nature Reviews Cancer 17 (4), 254, 2017
2872017
Risk determination and prevention of breast cancer
A Howell, AS Anderson, RB Clarke, SW Duffy, DG Evans, ...
Breast Cancer Research 16 (5), 1-19, 2014
2782014
The proliferation of normal human breast tissue implanted into athymic nude mice is stimulated by estrogen but not progesterone
IJ Laidlaw, RB Clarke, A Howell, AW Owen, CS Potten, E Anderson
Endocrinology 136 (1), 164-171, 1995
2341995
Estrogen responsiveness and control of normal human breast proliferation
E Anderson, RB Clarke, A Howell
Journal of mammary gland biology and neoplasia 3 (1), 23-35, 1998
2231998
The centrosomal kinase Nek2 displays elevated levels of protein expression in human breast cancer
DG Hayward, RB Clarke, AJ Faragher, MR Pillai, IM Hagan, AM Fry
Cancer research 64 (20), 7370-7376, 2004
1862004
Steroid receptors and cell cycle in normal mammary epithelium
E Anderson, RB Clarke
Journal of mammary gland biology and neoplasia 9 (1), 3-13, 2004
1822004
Targeting CXCR1/2 significantly reduces breast cancer stem cell activity and increases the efficacy of inhibiting HER2 via HER2-dependent and-independent mechanisms
JK Singh, G Farnie, NJ Bundred, BM Simoes, A Shergill, G Landberg, ...
Clinical cancer research 19 (3), 643-656, 2013
1742013
Recent advances reveal IL-8 signaling as a potential key to targeting breast cancer stem cells
JK Singh, BM Simões, SJ Howell, G Farnie, RB Clarke
Breast Cancer Research 15 (4), 210, 2013
1712013
Origins of breast cancer subtypes and therapeutic implications
AH Sims, A Howell, SJ Howell, RB Clarke
Nature Clinical Practice Oncology 4 (9), 516-525, 2007
1652007
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