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Jesus F. Barajas, Ph.D.
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Evolution-guided engineering of small-molecule biosensors
T Snoek, EK Chaberski, F Ambri, S Kol, SP Bjørn, B Pang, JF Barajas, ...
Nucleic acids research 48 (1), e3-e3, 2020
1352020
Engineered polyketides: Synergy between protein and host level engineering
JF Barajas, JM Blake-Hedges, CB Bailey, S Curran, JD Keasling
Synthetic and systems biotechnology 2 (3), 147-166, 2017
1122017
Development of Next Generation Synthetic Biology Tools for Use in Streptomyces venezuelae
RM Phelan, D Sachs, SJ Petkiewicz, JF Barajas, JM Blake-Hedges, ...
ACS synthetic biology 6 (1), 159-166, 2017
862017
The Arabidopsis Cell Cycle Checkpoint Regulators TANMEI/ALT2 and ATR Mediate the Active Process of Aluminum-Dependent Root Growth Inhibition
CD Nezames, CA Sjogren, JF Barajas, PB Larsen
The Plant Cell 24 (2), 608-621, 2012
852012
Development of a transcription factor-based lactam biosensor
J Zhang, JF Barajas, M Burdu, TL Ruegg, B Dias, JD Keasling
ACS synthetic biology 6 (3), 439-445, 2017
822017
Application of an Acyl-CoA Ligase from Streptomyces aizunensis for Lactam Biosynthesis
J Zhang, JF Barajas, M Burdu, G Wang, EE Baidoo, JD Keasling
ACS Synthetic Biology 6 (5), 884-890, 2017
742017
Comprehensive structural and biochemical analysis of the terminal myxalamid reductase domain for the engineered production of primary alcohols
JF Barajas, RM Phelan, AJ Schaub, JT Kliewer, PJ Kelly, DR Jackson, ...
Chemistry & biology 22 (8), 1018-1029, 2015
692015
Massively Parallel Fitness Profiling Reveals Multiple Novel Enzymes in Pseudomonas putida Lysine Metabolism
MG Thompson, JM Blake-Hedges, P Cruz-Morales, JF Barajas, ...
MBio 10 (3), 10.1128/mbio. 02577-18, 2019
68*2019
Molecular basis for interactions between an acyl carrier protein and a ketosynthase
JC Milligan, DJ Lee, DR Jackson, AJ Schaub, J Beld, JF Barajas, JJ Hale, ...
Nature chemical biology 15 (7), 669-671, 2019
522019
Isolation and characterization of novel mutations in the pSC101 origin that increase copy number
MG Thompson, N Sedaghatian, JF Barajas, M Wehrs, CB Bailey, ...
Scientific reports 8 (1), 1590, 2018
492018
Structural and functional analysis of two di-domain aromatase/cyclases from type II polyketide synthases
G Caldara-Festin, DR Jackson, JF Barajas, TR Valentic, AB Patel, ...
Proceedings of the National Academy of Sciences 112 (50), E6844-E6851, 2015
412015
Identification, Characterization, and Application of a Highly Sensitive Lactam Biosensor from Pseudomonas putida
MG Thompson, AN Pearson, JF Barajas, P Cruz-Morales, N Sedaghatian, ...
ACS synthetic biology 9 (1), 53-62, 2019
402019
Modeling linear and cyclic PKS intermediates through atom replacement
G Shakya, H Rivera Jr, DJ Lee, MJ Jaremko, JJ La Clair, DT Fox, ...
Journal of the American Chemical Society 136 (48), 16792-16799, 2014
322014
Structural insights into anthranilate priming during type II polyketide biosynthesis
DR Jackson, SS Tu, MC Nguyen, JF Barajas, AJ Schaub, D Krug, ...
ACS chemical biology 11 (1), 95-103, 2016
302016
Polyketide mimetics yield structural and mechanistic insights into product template domain function in nonreducing polyketide synthases
JF Barajas, G Shakya, G Moreno, H Rivera Jr, DR Jackson, CL Topper, ...
Proceedings of the National Academy of Sciences 114 (21), E4142-E4148, 2017
292017
Chemoinformatic-guided engineering of polyketide synthases
A Zargar, R Lal, L Valencia, J Wang, TWH Backman, P Cruz-Morales, ...
Journal of the American Chemical Society 142 (22), 9896-9901, 2020
272020
Insights into complex oxidation during BE-7585A biosynthesis: structural determination and analysis of the polyketide monooxygenase BexE
DR Jackson, X Yu, G Wang, AB Patel, J Calveras, JF Barajas, E Sasaki, ...
ACS chemical biology 11 (4), 1137-1147, 2016
162016
Biochemical Characterization of β‐Amino Acid Incorporation in Fluvirucin B2 Biosynthesis
JF Barajas, A Zargar, B Pang, VT Benites, J Gin, EEK Baidoo, CJ Petzold, ...
ChemBioChem 19 (13), 1391-1395, 2018
152018
Structural and biochemical analysis of protein–protein interactions between the acyl‐carrier protein and product template domain
JF Barajas, K Finzel, TR Valentic, G Shakya, N Gamarra, D Martinez, ...
Angewandte Chemie International Edition 55 (42), 13005-13009, 2016
152016
An iron (II) dependent oxygenase performs the last missing step of plant lysine catabolism
MG Thompson, JM Blake-Hedges, JH Pereira, JA Hangasky, MS Belcher, ...
Nature communications 11 (1), 2931, 2020
142020
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Articles 1–20