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Eric J. M. Lang
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Allosteric ACTion: the varied ACT domains regulating enzymes of amino-acid metabolism
EJM Lang, PJ Cross, G Mittelstädt, GB Jameson, EJ Parker
Current opinion in structural biology 29, 102-111, 2014
822014
De Novo-Designed α-Helical Barrels as Receptors for Small Molecules
F Thomas, WM Dawson, EJM Lang, AJ Burton, GJ Bartlett, GG Rhys, ...
ACS Synthetic Biology 7 (7), 1808-1816, 2018
722018
Constructing ion channels from water-soluble α-helical barrels
AJ Scott, A Niitsu, HT Kratochvil, EJM Lang, JT Sengel, WM Dawson, ...
Nature chemistry 13 (7), 643-650, 2021
672021
Maintaining and breaking symmetry in homomeric coiled-coil assemblies
GG Rhys, CW Wood, EJM Lang, AJ Mulholland, RL Brady, AR Thomson, ...
Nature communications 9 (1), 4132, 2018
602018
Structural resolution of switchable states of a de novo peptide assembly
WM Dawson, EJM Lang, GG Rhys, KL Shelley, C Williams, RL Brady, ...
Nature Communications 12 (1), 1530, 2021
232021
Interdomain Conformational Changes Provide Allosteric Regulation en Route to Chorismate*♦
AR Nazmi, EJM Lang, Y Bai, TM Allison, MH Othman, S Panjikar, ...
Journal of Biological Chemistry 291 (42), 21836-21847, 2016
232016
Calculated pKa Variations Expose Dynamic Allosteric Communication Networks
EJM Lang, LC Heyes, GB Jameson, EJ Parker
Journal of the American Chemical Society 138 (6), 2036-2045, 2016
232016
Structural and functional characterisation of the entry point to pyocyanin biosynthesis in Pseudomonas aeruginosa defines a new 3-deoxy-d-arabino-heptulosonate 7-phosphate …
OW Sterritt, EJM Lang, SA Kessans, TM Ryan, B Demeler, GB Jameson, ...
Bioscience Reports 38 (5), BSR20181605, 2018
172018
Generalized Born Implicit Solvent Models Do Not Reproduce Secondary Structures of De Novo Designed Glu/Lys Peptides
EJM Lang, EG Baker, DN Woolfson, AJ Mulholland
Journal of chemical theory and computation 18 (7), 4070-4076, 2022
132022
Multiscale workflow for modeling ligand complexes of zinc metalloproteins
Z Yang, RM Twidale, S Gervasoni, R Suardíaz, CK Colenso, EJM Lang, ...
Journal of Chemical Information and Modeling 61 (11), 5658-5672, 2021
122021
Resistance to the “last resort” antibiotic colistin: a single-zinc mechanism for phosphointermediate formation in MCR enzymes
E Lythell, R Suardíaz, P Hinchliffe, C Hanpaibool, S Visitsatthawong, ...
Chemical communications 56 (50), 6874-6877, 2020
122020
Industrial applications of chiral chromatography
J Bléhaut, P Franco, T Zhang, E Lang, E Valéry, JF Marcoux
Reference module in chemistry, molecular sciences and chemical engineering …, 2012
12*2012
Diverse allosteric componentry and mechanisms control entry into aromatic metabolite biosynthesis
W Jiao, EJM Lang, Y Bai, Y Fan, EJ Parker
Current Opinion in Structural Biology 65, 159-167, 2020
102020
Domain cross-talk within a bifunctional enzyme provides catalytic and allosteric functionality in the biosynthesis of aromatic amino acids
Y Bai, EJM Lang, AR Nazmi, EJ Parker
Journal of Biological Chemistry 294 (13), 4828-4842, 2019
92019
Preparative and Industrial Scale Chromatography: Green and Integrated Processes
E Lang, E Valéry, O Ludemann-Hombourger, W Majewski, J Bléhaut
Green Chemistry in the Pharmaceutical Industry, 243-268, 2010
32010
Molecular Dynamics, Quantum Mechanics, and Combined Quantum Mechanics/Molecular Mechanics Methods for Drug Discovery and Development
EJM Lang, AJ Mulholland
Reference Module in Chemistry, Molecular Sciences and Chemical Engineering, 2017
12017
Implicit solvent models fail to reproduce secondary structures of de novo designed peptides
E Lang, E Baker, D Woolfson, A Mulholland
2021
Automated Peptide Synthesis
E Lang, J Blehaut
ChemInform 40 (40), no-no, 2009
2009
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Articles 1–18