Controlled Human Infection and Rechallenge with Streptococcus pneumoniae Reveals the Protective Efficacy of Carriage in Healthy Adults DM Ferreira, DR Neill, M Bangert, JF Gritzfeld, N Green, AKA Wright, ... American journal of respiratory and critical care medicine 187 (8), 855-864, 2013 | 201 | 2013 |
Prioritization of anti‐SARS‐Cov‐2 drug repurposing opportunities based on plasma and target site concentrations derived from their established human pharmacokinetics U Arshad, H Pertinez, H Box, L Tatham, RKR Rajoli, P Curley, M Neary, ... Clinical Pharmacology & Therapeutics 108 (4), 775-790, 2020 | 154 | 2020 |
Agglutination by anti-capsular polysaccharide antibody is associated with protection against experimental human pneumococcal carriage E Mitsi, AM Roche, J Reiné, T Zangari, JT Owugha, SH Pennington, ... Mucosal immunology 10 (2), 385-394, 2017 | 99 | 2017 |
Experimental human pneumococcal carriage JF Gritzfeld, AD Wright, AM Collins, SH Pennington, AKA Wright, ... JoVE (Journal of Visualized Experiments), e50115, 2013 | 97 | 2013 |
First human challenge testing of a pneumococcal vaccine. Double-blind randomized controlled trial AM Collins, AD Wright, E Mitsi, JF Gritzfeld, CA Hancock, SH Pennington, ... American journal of respiratory and critical care medicine 192 (7), 853-858, 2015 | 93 | 2015 |
Polysaccharide-specific memory B cells predict protection against experimental human pneumococcal carriage SH Pennington, S Pojar, E Mitsi, JF Gritzfeld, E Nikolaou, C Solorzano, ... American journal of respiratory and critical care medicine 194 (12), 1523-1531, 2016 | 64 | 2016 |
Dose prediction for repurposing nitazoxanide in SARS‐CoV‐2 treatment or chemoprophylaxis RKR Rajoli, H Pertinez, U Arshad, H Box, L Tatham, P Curley, M Neary, ... British Journal of Clinical Pharmacology 87 (4), 2078-2088, 2021 | 63 | 2021 |
Immunomodulatory adjuvant therapy in severe community-acquired pneumonia B Morton, SH Pennington, SB Gordon Expert Review of Respiratory Medicine 8 (5), 587-596, 2014 | 53 | 2014 |
Modulation of nasopharyngeal innate defenses by viral coinfection predisposes individuals to experimental pneumococcal carriage S Glennie, JF Gritzfeld, SH Pennington, M Garner-Jones, N Coombes, ... Mucosal immunology 9 (1), 56-67, 2016 | 47 | 2016 |
Therapeutic potential of nitazoxanide: an appropriate choice for repurposing versus SARS-CoV-2? AV Stachulski, J Taujanskas, SL Pate, RKR Rajoli, G Aljayyoussi, ... ACS infectious diseases 7 (6), 1317-1331, 2020 | 41 | 2020 |
A retrospective evaluation of critical care blood culture yield–do support services contribute to the “weekend effect”? B Morton, S Nagaraja, A Collins, SH Pennington, JD Blakey PLoS One 10 (10), e0141361, 2015 | 38 | 2015 |
Treatment responses to Azithromycin and Ciprofloxacin in uncomplicated Salmonella Typhi infection: A comparison of Clinical and Microbiological Data from a … C Jin, MM Gibani, SH Pennington, X Liu, A Ardrey, G Aljayyoussi, ... PLoS neglected tropical diseases 13 (12), e0007955, 2019 | 33 | 2019 |
Oral Typhoid Vaccination With Live-Attenuated Salmonella Typhi Strain Ty21a Generates Ty21a-Responsive and Heterologous Influenza Virus–Responsive CD4+ and CD8 … SH Pennington, AL Thompson, AKA Wright, DM Ferreira, KC Jambo, ... The Journal of infectious diseases 213 (11), 1809-1819, 2016 | 31 | 2016 |
SARS-CoV-2 infects an upper airway model derived from induced pluripotent stem cells I Djidrovski, M Georgiou, GL Hughes, EI Patterson, A Casas-Sanchez, ... Stem cells 39 (10), 1310-1321, 2021 | 23 | 2021 |
Augmented passive immunotherapy with P4 peptide improves phagocyte activity in severe sepsis B Morton, E Mitsi, SH Pennington, J Reiné, AD Wright, R Parker, ... Shock 46 (6), 635-641, 2016 | 20 | 2016 |
Sequential infection with influenza A virus followed by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) leads to more severe disease and encephalitis in a mouse … JJ Clark, R Penrice-Randal, P Sharma, A Kipar, X Dong, SH Pennington, ... bioRxiv, 2020.10. 13.334532, 2020 | 19 | 2020 |
Prioritisation of potential anti-SARS-CoV-2 drug repurposing opportunities based on ability to achieve adequate plasma and target site concentrations derived from their … U Arshad, H Pertinez, H Box, L Tatham, RKR Rajoli, P Curley, M Neary, ... medRxiv, 2020.04. 16.20068379, 2020 | 18 | 2020 |
Nonspecific effects of oral vaccination with live-attenuated Salmonella Typhi strain Ty21a SH Pennington, DM Ferreira, E Caamaño-Gutiérrez, J Reiné, C Hewitt, ... Science Advances 5 (2), eaau6849, 2019 | 15 | 2019 |
Remdesivir–ivermectin combination displays synergistic interaction with improved in vitro activity against SARS-CoV-2 LN Jeffreys, SH Pennington, J Duggan, CH Caygill, RC Lopeman, ... International Journal of Antimicrobial Agents 59 (3), 106542, 2022 | 14 | 2022 |
The whole blood phagocytosis assay: a clinically relevant test of neutrophil function and dysfunction in community-acquired pneumonia J Reiné, J Rylance, DM Ferreira, SH Pennington, ID Welters, R Parker, ... BMC Research Notes 13, 1-5, 2020 | 11 | 2020 |