Stratification of pancreatic ductal adenocarcinomas based on tumor and microenvironment features F Puleo, R Nicolle, Y Blum, J Cros, L Marisa, P Demetter, E Quertinmont, ... Gastroenterology 155 (6), 1999-2013. e3, 2018 | 426 | 2018 |
Distinct epigenetic landscapes underlie the pathobiology of pancreatic cancer subtypes G Lomberk, Y Blum, R Nicolle, A Nair, KS Gaonkar, L Marisa, A Mathison, ... Nature communications 9 (1), 1978, 2018 | 210 | 2018 |
Pancreatic adenocarcinoma therapeutic targets revealed by tumor-stroma cross-talk analyses in patient-derived xenografts R Nicolle, Y Blum, L Marisa, C Loncle, O Gayet, V Moutardier, O Turrini, ... Cell reports 21 (9), 2458-2470, 2017 | 162 | 2017 |
Deregulation of Rab and Rab Effector Genes in Bladder Cancer JR Ho, E Chapeaublanc, L Kirkwood, R Nicolle, S Benhamou, T Lebret, ... PloS one 7 (6), e39469, 2012 | 126 | 2012 |
Basal-like and Classical cells coexistence in pancreatic cancer revealed by single cell analysis N Juiz, A Elkaoutari, M Bigonnet, O Gayet, J Roques, R Nicolle, J Iovanna, ... bioRxiv, 2020.01. 07.897454, 2020 | 112 | 2020 |
Integrated molecular characterization of chondrosarcoma reveals critical determinants of disease progression R Nicolle, M Ayadi, A Gomez-Brouchet, L Armenoult, G Banneau, ... Nature communications 10 (1), 4622, 2019 | 77 | 2019 |
Establishment of a pancreatic adenocarcinoma molecular gradient (PAMG) that predicts the clinical outcome of pancreatic cancer R Nicolle, Y Blum, P Duconseil, C Vanbrugghe, N Brandone, F Poizat, ... EBioMedicine 57, 2020 | 75 | 2020 |
Gene expression profiling of patient‐derived pancreatic cancer xenografts predicts sensitivity to the BET bromodomain inhibitor JQ 1: implications for individualized medicine … B Bian, M Bigonnet, O Gayet, C Loncle, A Maignan, M Gilabert, ... EMBO molecular medicine 9 (4), 482-497, 2017 | 73 | 2017 |
A transcriptomic signature to predict adjuvant gemcitabine sensitivity in pancreatic adenocarcinoma R Nicolle, O Gayet, P Duconseil, C Vanbrugghe, J Roques, M Bigonnet, ... Annals of Oncology 32 (2), 250-260, 2021 | 63 | 2021 |
COREGNET: reconstruction and integrated analysis of co-regulatory networks R Nicolle, F Radvanyi, M Elati Bioinformatics, btv305, 2015 | 63 | 2015 |
Different shades of pancreatic ductal adenocarcinoma, different paths towards precision therapeutic applications S Martens, P Lefesvre, R Nicolle, AV Biankin, F Puleo, JL Van Laethem, ... Annals of Oncology 30 (9), 1428-1436, 2019 | 58 | 2019 |
An FGFR 3/MYC positive feedback loop provides new opportunities for targeted therapies in bladder cancers M Mahe, F Dufour, H Neyret‐Kahn, A Moreno‐Vega, C Beraud, M Shi, ... EMBO molecular medicine 10 (4), e8163, 2018 | 55 | 2018 |
Performance of next-generation sequencing for the detection of microsatellite instability in colorectal cancer with deficient DNA mismatch repair T Ratovomanana, R Cohen, M Svrcek, F Renaud, P Cervera, A Siret, ... Gastroenterology 161 (3), 814-826. e7, 2021 | 47 | 2021 |
PPAPDC1B and WHSC1L1 are common drivers of the 8p11-12 amplicon, not only in breast tumors but also in pancreatic adenocarcinomas and lung tumors SF Mahmood, N Gruel, R Nicolle, E Chapeaublanc, O Delattre, ... The American journal of pathology 183 (5), 1634-1644, 2013 | 38 | 2013 |
Specific genomic alterations in high-grade pulmonary neuroendocrine tumours with carcinoid morphology J Cros, N Théou-Anton, V Gounant, R Nicolle, C Reyes, S Humez, ... Neuroendocrinology 111 (1-2), 158-169, 2020 | 35 | 2020 |
Prognostic biomarkers in pancreatic cancer: avoiding errata when using the TCGA dataset R Nicolle, J Raffenne, V Paradis, A Couvelard, A de Reynies, Y Blum, ... Cancers 11 (1), 126, 2019 | 35 | 2019 |
hENT1 testing in pancreatic ductal adenocarcinoma: are we ready? a multimodal evaluation of hENT1 status J Raffenne, R Nicolle, F Puleo, D Le Corre, C Boyez, R Marechal, ... Cancers 11 (11), 1808, 2019 | 28 | 2019 |
Pancreatic cancer prognosis is predicted by an ATAC-array technology for assessing chromatin accessibility S Dhara, S Chhangawala, H Chintalapudi, G Askan, V Aveson, AL Massa, ... Nature Communications 12 (1), 3044, 2021 | 25 | 2021 |
Cancer-associated fibroblasts: accomplices in the tumor immune evasion M Hilmi, R Nicolle, C Bousquet, C Neuzillet Cancers 12 (10), 2969, 2020 | 25 | 2020 |
Pharmacologic normalization of pancreatic cancer-associated fibroblast secretome impairs prometastatic cross-talk with macrophages R Samain, A Brunel, T Douché, M Fanjul, S Cassant-Sourdy, J Rochotte, ... Cellular and molecular gastroenterology and hepatology 11 (5), 1405-1436, 2021 | 24 | 2021 |