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BRIAN WALKER
BRIAN WALKER
Professor of Biomedicinal Chemistry, Queen's University Belfast
Verified email at qub.ac.uk
Title
Cited by
Cited by
Year
Proteasome inhibitors in cancer therapy
LJ Crawford, B Walker, AE Irvine
Journal of cell communication and signaling 5, 101-110, 2011
4122011
Neutrophil elastase activity is associated with exacerbations and lung function decline in bronchiectasis
JD Chalmers, KL Moffitt, G Suarez-Cuartin, O Sibila, S Finch, E Furrie, ...
American journal of respiratory and critical care medicine 195 (10), 1384-1393, 2017
2922017
The membrane-anchored serine protease, TMPRSS2, activates PAR-2 in prostate cancer cells
S Wilson, B Greer, J Hooper, A Zijlstra, B Walker, J Quigley, S Hawthorne
Biochemical Journal 388 (3), 967-972, 2005
2282005
Comparative selectivity and specificity of the proteasome inhibitors BzLLLCOCHO, PS-341, and MG-132
LJA Crawford, B Walker, H Ovaa, D Chauhan, KC Anderson, TCM Morris, ...
Cancer research 66 (12), 6379-6386, 2006
1892006
Strategies for the inhibition of serine proteases
B Walker, JF Lynas
Cellular and Molecular Life Sciences CMLS 58, 596-624, 2001
1522001
The clinical significance of cathepsin S expression in human astrocytomas
T Flannery, D Gibson, M Mirakhur, S McQuaid, C Greenan, A Trimble, ...
The American journal of pathology 163 (1), 175-182, 2003
1302003
Organophosphorus Chemistry: Volume 21
BJ Walker, JB Hobbs
Royal Society of chemistry, 2007
1282007
Novel inhibitors of the Pseudomonas aeruginosa virulence factor LasB: a potential therapeutic approach for the attenuation of virulence mechanisms in pseudomonal infection
GRA Cathcart, D Quinn, B Greer, P Harriott, JF Lynas, BF Gilmore, ...
Antimicrobial agents and chemotherapy 55 (6), 2670-2678, 2011
1232011
Protease-activated receptor-2 involvement in hypotension in normal and endotoxemic rats in vivo
C Cicala, A Pinto, M Bucci, R Sorrentino, B Walker, P Harriot, A Cruchley, ...
Circulation 99 (19), 2590-2597, 1999
1191999
The synthesis of peptidylfluoromethanes and their properties as inhibitors of serine proteinases and cysteine proteinases
P Rauber, H Angliker, B Walker, E Shaw
Biochemical Journal 239 (3), 633-640, 1986
1191986
Antibody-mediated inhibition of cathepsin S blocks colorectal tumor invasion and angiogenesis
RE Burden, JA Gormley, TJ Jaquin, DM Small, DJ Quinn, SM Hegarty, ...
Clinical Cancer Research 15 (19), 6042-6051, 2009
1132009
Antimicrobial/cytolytic peptides from the venom of the North African scorpion, Androctonus amoreuxi: biochemical and functional characterization of natural peptides and a …
A Almaaytah, M Zhou, L Wang, T Chen, B Walker, C Shaw
Peptides 35 (2), 291-299, 2012
1082012
A sequence within the cytoplasmic tail of GpIIb independently activates platelet aggregation and thromboxane synthesis
G Stephens, N O'Luanaigh, D Reilly, P Harriott, B Walker, D Fitzgerald, ...
Journal of Biological Chemistry 273 (32), 20317-20322, 1998
1081998
Cathepsin S from both tumor and tumor‐associated cells promote cancer growth and neovascularization
DM Small, RE Burden, J Jaworski, SM Hegarty, S Spence, JF Burrows, ...
International journal of cancer 133 (9), 2102-2112, 2013
1042013
Mucosal allergic sensitization to cockroach allergens is dependent on proteinase activity and proteinase-activated receptor-2 activation
NG Arizmendi, M Abel, K Mihara, C Davidson, D Polley, A Nadeem, ...
The Journal of Immunology 186 (5), 3164-3172, 2011
1042011
A highly convenient route to optically pure α-aminophosphonic acids
R Hamilton, B Walker, BJ Walker
Tetrahedron letters 36 (25), 4451-4454, 1995
1001995
Irreversible inhibition of the bacterial cysteine protease-transpeptidase sortase (SrtA) by substrate-derived affinity labels
CJ Scott, A McDOWELL, SL Martin, JF Lynas, K Vandenbroeck, B Walker
Biochemical Journal 366 (3), 953-958, 2002
982002
Importance of the P4′ residue in human granzyme B inhibitors and substrates revealed by scanning mutagenesis of the proteinase inhibitor 9 reactive center loop
J Sun, JC Whisstock, P Harriott, B Walker, A Novak, PE Thompson, ...
Journal of Biological Chemistry 276 (18), 15177-15184, 2001
962001
Cathepsin S expression: an independent prognostic factor in glioblastoma tumours—a pilot study
T Flannery, S McQuaid, C McGoohan, RS McConnell, G McGregor, ...
International journal of cancer 119 (4), 854-860, 2006
942006
Identification of potential activators of proteinase‐activated receptor‐2 1
MT Fox, P Harriott, B Walker, SR Stone
FEBS letters 417 (3), 267-269, 1997
901997
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