Proteasome inhibitors in cancer therapy LJ Crawford, B Walker, AE Irvine Journal of cell communication and signaling 5, 101-110, 2011 | 412 | 2011 |
Neutrophil elastase activity is associated with exacerbations and lung function decline in bronchiectasis JD Chalmers, KL Moffitt, G Suarez-Cuartin, O Sibila, S Finch, E Furrie, ... American journal of respiratory and critical care medicine 195 (10), 1384-1393, 2017 | 292 | 2017 |
The membrane-anchored serine protease, TMPRSS2, activates PAR-2 in prostate cancer cells S Wilson, B Greer, J Hooper, A Zijlstra, B Walker, J Quigley, S Hawthorne Biochemical Journal 388 (3), 967-972, 2005 | 228 | 2005 |
Comparative selectivity and specificity of the proteasome inhibitors BzLLLCOCHO, PS-341, and MG-132 LJA Crawford, B Walker, H Ovaa, D Chauhan, KC Anderson, TCM Morris, ... Cancer research 66 (12), 6379-6386, 2006 | 189 | 2006 |
Strategies for the inhibition of serine proteases B Walker, JF Lynas Cellular and Molecular Life Sciences CMLS 58, 596-624, 2001 | 152 | 2001 |
The clinical significance of cathepsin S expression in human astrocytomas T Flannery, D Gibson, M Mirakhur, S McQuaid, C Greenan, A Trimble, ... The American journal of pathology 163 (1), 175-182, 2003 | 130 | 2003 |
Organophosphorus Chemistry: Volume 21 BJ Walker, JB Hobbs Royal Society of chemistry, 2007 | 128 | 2007 |
Novel inhibitors of the Pseudomonas aeruginosa virulence factor LasB: a potential therapeutic approach for the attenuation of virulence mechanisms in pseudomonal infection GRA Cathcart, D Quinn, B Greer, P Harriott, JF Lynas, BF Gilmore, ... Antimicrobial agents and chemotherapy 55 (6), 2670-2678, 2011 | 123 | 2011 |
Protease-activated receptor-2 involvement in hypotension in normal and endotoxemic rats in vivo C Cicala, A Pinto, M Bucci, R Sorrentino, B Walker, P Harriot, A Cruchley, ... Circulation 99 (19), 2590-2597, 1999 | 119 | 1999 |
The synthesis of peptidylfluoromethanes and their properties as inhibitors of serine proteinases and cysteine proteinases P Rauber, H Angliker, B Walker, E Shaw Biochemical Journal 239 (3), 633-640, 1986 | 119 | 1986 |
Antibody-mediated inhibition of cathepsin S blocks colorectal tumor invasion and angiogenesis RE Burden, JA Gormley, TJ Jaquin, DM Small, DJ Quinn, SM Hegarty, ... Clinical Cancer Research 15 (19), 6042-6051, 2009 | 113 | 2009 |
Antimicrobial/cytolytic peptides from the venom of the North African scorpion, Androctonus amoreuxi: biochemical and functional characterization of natural peptides and a … A Almaaytah, M Zhou, L Wang, T Chen, B Walker, C Shaw Peptides 35 (2), 291-299, 2012 | 108 | 2012 |
A sequence within the cytoplasmic tail of GpIIb independently activates platelet aggregation and thromboxane synthesis G Stephens, N O'Luanaigh, D Reilly, P Harriott, B Walker, D Fitzgerald, ... Journal of Biological Chemistry 273 (32), 20317-20322, 1998 | 108 | 1998 |
Cathepsin S from both tumor and tumor‐associated cells promote cancer growth and neovascularization DM Small, RE Burden, J Jaworski, SM Hegarty, S Spence, JF Burrows, ... International journal of cancer 133 (9), 2102-2112, 2013 | 104 | 2013 |
Mucosal allergic sensitization to cockroach allergens is dependent on proteinase activity and proteinase-activated receptor-2 activation NG Arizmendi, M Abel, K Mihara, C Davidson, D Polley, A Nadeem, ... The Journal of Immunology 186 (5), 3164-3172, 2011 | 104 | 2011 |
A highly convenient route to optically pure α-aminophosphonic acids R Hamilton, B Walker, BJ Walker Tetrahedron letters 36 (25), 4451-4454, 1995 | 100 | 1995 |
Irreversible inhibition of the bacterial cysteine protease-transpeptidase sortase (SrtA) by substrate-derived affinity labels CJ Scott, A McDOWELL, SL Martin, JF Lynas, K Vandenbroeck, B Walker Biochemical Journal 366 (3), 953-958, 2002 | 98 | 2002 |
Importance of the P4′ residue in human granzyme B inhibitors and substrates revealed by scanning mutagenesis of the proteinase inhibitor 9 reactive center loop J Sun, JC Whisstock, P Harriott, B Walker, A Novak, PE Thompson, ... Journal of Biological Chemistry 276 (18), 15177-15184, 2001 | 96 | 2001 |
Cathepsin S expression: an independent prognostic factor in glioblastoma tumours—a pilot study T Flannery, S McQuaid, C McGoohan, RS McConnell, G McGregor, ... International journal of cancer 119 (4), 854-860, 2006 | 94 | 2006 |
Identification of potential activators of proteinase‐activated receptor‐2 1 MT Fox, P Harriott, B Walker, SR Stone FEBS letters 417 (3), 267-269, 1997 | 90 | 1997 |