Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism Z Hu, D Zhu, W Wang, W Li, W Jia, X Zeng, W Ding, L Yu, X Wang, ... Nature genetics 47 (2), 158-163, 2015 | 493 | 2015 |
The precision prevention and therapy of HPV‐related cervical cancer: new concepts and clinical implications Z Hu, D Ma Cancer medicine 7 (10), 5217-5236, 2018 | 306 | 2018 |
Disruption of HPV16-E7 by CRISPR/Cas system induces apoptosis and growth inhibition in HPV16 positive human cervical cancer cells Z Hu, L Yu, D Zhu, W Ding, X Wang, C Zhang, L Wang, X Jiang, H Shen, ... BioMed research international 2014, 2014 | 214 | 2014 |
TALEN-mediated targeting of HPV oncogenes ameliorates HPV-related cervical malignancy Z Hu, W Ding, D Zhu, L Yu, X Jiang, X Wang, C Zhang, L Wang, T Ji, D Liu, ... The Journal of clinical investigation 125 (1), 425-436, 2015 | 123 | 2015 |
LNMICC promotes nodal metastasis of cervical cancer by reprogramming fatty acid metabolism C Shang, W Wang, Y Liao, Y Chen, T Liu, Q Du, J Huang, Y Liang, J Liu, ... Cancer research 78 (4), 877-890, 2018 | 111 | 2018 |
Hyperbranched poly (β-amino ester) based polyplex nanopaticles for delivery of CRISPR/Cas9 system and treatment of HPV infection associated cervical cancer X Gao, Z Jin, X Tan, C Zhang, C Zou, W Zhang, J Ding, BC Das, ... Journal of controlled release 321, 654-668, 2020 | 69 | 2020 |
Zinc Finger Nucleases Targeting the Human Papillomavirus E7 Oncogene Induce E7 Disruption and a Transformed Phenotype in HPV16/18-Positive Cervical … W Ding, Z Hu, D Zhu, X Jiang, L Yu, X Wang, C Zhang, L Wang, T Ji, K Li, ... Clinical cancer research 20 (24), 6495-6503, 2014 | 65 | 2014 |
HPV-CCDC106 integration alters local chromosome architecture and hijacks an enhancer by three-dimensional genome structure remodeling in cervical cancer C Cao, P Hong, X Huang, D Lin, G Cao, L Wang, B Feng, P Wu, H Shen, ... Journal of genetics and genomics 47 (8), 437-450, 2020 | 49 | 2020 |
Amplification and overexpression of TP63 and MYC as biomarkers for transition of cervical intraepithelial neoplasia to cervical cancer. D Zhu, XH Jiang, YH Jiang, WC Ding, C Zhang, H Shen, XL Wang, D Ma, ... International Journal of Gynecologic Cancer 24 (4), 643-648, 2014 | 42* | 2014 |
Fibulin-5 is down-regulated in urothelial carcinoma of bladder and inhibits growth and invasion of human bladder cancer cell line 5637 Z Hu, Q Ai, H Xu, X Ma, H Li, T Shi, C Wang, D Gong, X Zhang Urologic Oncology: Seminars and Original Investigations 29 (4), 430-435, 2011 | 42 | 2011 |
Periostin+cancer‐associated fibroblasts promote lymph node metastasis by impairing the lymphatic endothelial barriers in cervical squamous cell carcinoma WF Wei, XJ Chen, LJ Liang, L Yu, XG Wu, CF Zhou, ZC Wang, LS Fan, ... Molecular Oncology 15 (1), 210-227, 2021 | 34 | 2021 |
Tripartite motif containing 62 is a novel prognostic marker and suppresses tumor metastasis via c-Jun/Slug signaling-mediated epithelial-mesenchymal transition in cervical cancer TY Liu, J Chen, CL Shang, HW Shen, JM Huang, YC Liang, W Wang, ... Journal of Experimental & Clinical Cancer Research 35, 1-20, 2016 | 34 | 2016 |
In vitro and in vivo growth inhibition of human cervical cancer cells via human papillomavirus E6/E7 mRNAs’ cleavage by CRISPR/Cas13a system Y Chen, H Jiang, T Wang, D He, R Tian, Z Cui, X Tian, Q Gao, X Ma, ... Antiviral Research 178, 104794, 2020 | 33 | 2020 |
The comparison of ZFNs, TALENs, and SpCas9 by GUIDE-seq in HPV-targeted gene therapy Z Cui, H Liu, H Zhang, Z Huang, R Tian, L Li, W Fan, Y Chen, L Chen, ... Molecular Therapy-Nucleic Acids 26, 1466-1478, 2021 | 28 | 2021 |
FrCas9 is a CRISPR/Cas9 system with high editing efficiency and fidelity Z Cui, R Tian, Z Huang, Z Jin, L Li, J Liu, Z Huang, H Xie, D Liu, H Mo, ... Nature Communications 13 (1), 1425, 2022 | 25 | 2022 |
Risk stratification of cervical lesions using capture sequencing and machine learning method based on HPV and human integrated genomic profiles Carcinogenesis 40 (10), 1220–1228, 2019 | 25 | 2019 |
An effective vaginal gel to deliver CRISPR/Cas9 system encapsulated in poly (β-amino ester) nanoparticles for vaginal gene therapy G Niu, Z Jin, C Zhang, D He, X Gao, C Zou, W Zhang, J Ding, BC Das, ... EBioMedicine 58, 2020 | 15 | 2020 |
Gene knock-out chain reaction enables high disruption efficiency of HPV18 E6/E7 genes in cervical cancer cells R Tian, J Liu, W Fan, R Li, Z Cui, Z Jin, Z Huang, H Xie, L Li, Z Huang, ... Molecular Therapy-Oncolytics 24, 171-179, 2022 | 14 | 2022 |
A fifteen‐gene classifier to predict neoadjuvant chemotherapy responses in patients with stage IB to IIB squamous cervical cancer X Tian, X Wang, Z Cui, J Liu, X Huang, C Shi, M Zhang, T Liu, X Du, R Li, ... Advanced Science 8 (10), 2001978, 2021 | 12 | 2021 |
Cytological immunostaining of HMGA2, LRP1B, and TP63 as potential biomarkers for triaging human papillomavirus-positive women Y Jiang, C Zhu, D He, Q Gao, X Tian, X Ma, J Wu, BC Das, K Severinov, ... Translational Oncology 12 (7), 959-967, 2019 | 11 | 2019 |