Modulation of cardiac ryanodine receptor 2 by calmodulin D Gong*, X Chi*, J Wei*, G Zhou, G Huang, L Zhang, R Wang, J Lei, ... Nature 572 (7769), 347-351, * co-first authors, 2019 | 148 | 2019 |
Cardiac ryanodine receptor calcium release deficiency syndrome B Sun, J Yao, M Ni, J Wei, X Zhong, W Guo, L Zhang, R Wang, D Belke, ... Science translational medicine 13 (579), eaba7287, 2021 | 84 | 2021 |
The cardiac ryanodine receptor, but not sarcoplasmic reticulum Ca2+-ATPase, is a major determinant of Ca2+ alternans in intact mouse hearts B Sun, J Wei, X Zhong, W Guo, J Yao, R Wang, A Vallmitjana, R Benitez, ... Journal of Biological Chemistry 293 (35), 13650-13661, 2018 | 40 | 2018 |
Enhanced cytosolic Ca2+ activation underlies a common defect of central domain cardiac ryanodine receptor mutations linked to arrhythmias Z Xiao, W Guo, B Sun, DJ Hunt, J Wei, Y Liu, Y Wang, R Wang, PP Jones, ... Journal of Biological Chemistry 291 (47), 24528-24537, 2016 | 37 | 2016 |
Trimetazidine protects cardiomyocytes against hypoxia-induced injury through ameliorates calcium homeostasis J Wei, H Xu, L Shi, J Tong, J Zhang Chemico-Biological Interactions 236, 47-56, 2015 | 37 | 2015 |
Effects of extremely low frequency electromagnetic fields on intracellular calcium transients in cardiomyocytes J Wei, J Sun, H Xu, L Shi, L Sun, J Zhang Electromagnetic Biology and Medicine 34 (1), 77-84, 2015 | 37 | 2015 |
Clinical and Functional Characterization of Ryanodine Receptor 2 Variants Implicated in Calcium-Release Deficiency Syndrome TM Roston*, J Wei*, W Guo, Y Li, X Zhong, R Wang, JP Estillore, ... JAMA Cardiology 7 (1), 84-92, * co-first authors, 2022 | 36 | 2022 |
Infanticide vs. inherited cardiac arrhythmias M Brohus, T Arsov, DA Wallace, HH Jensen, M Nyegaard, L Crotti, ... Europace 23 (3), 441-450, 2020 | 35 | 2020 |
Linking the heart and the brain: neurodevelopmental disorders in patients with catecholaminergic polymorphic ventricular tachycardia KVV Lieve, JMA Verhagen, J Wei, JM Bos, C van Der Werf, FR i Noguer, ... Heart Rhythm 16 (2), 220-228, 2019 | 35 | 2019 |
Identification of loss-of-function RyR2 mutations associated with idiopathic ventricular fibrillation and sudden death X Zhong, W Guo, J Wei, Y Tang, Y Liu, JZ Zhang, VH Tan, L Zhang, ... Bioscience Reports 41 (4), BSR20210209, 2021 | 31 | 2021 |
Ca2+-CaM Dependent Inactivation of RyR2 Underlies Ca2+ Alternans in Intact Heart J Wei, J Yao, D Belke, W Guo, X Zhong, B Sun, R Wang, JP Estillore, ... Circulation Research 128 (4), e63-e83, 2021 | 29 | 2021 |
Human RyR2 (Ryanodine Receptor 2) loss-of-function mutations: clinical phenotypes and in vitro characterization Y Li, J Wei, W Guo, B Sun, JP Estillore, R Wang, A Yoruk, TM Roston, ... Circulation: Arrhythmia and Electrophysiology 14 (9), e010013, 2021 | 28 | 2021 |
Reduced threshold for store overload-induced Ca2+ release is a common defect of RyR1 mutations associated with malignant hyperthermia and central core disease W Chen, A Koop, Y Liu, W Guo, J Wei, R Wang, DH MacLennan, ... Biochemical Journal 474 (16), 2749-2761, 2017 | 28 | 2017 |
Provocation Testing and Therapeutic Response in a Newly Described Channelopathy: RyR2 Calcium Release Deficiency Syndrome JOM Ormerod, E Ormondroyd, Y Li, J Taylor, J Wei, W Guo, R Wang, ... Circulation: Genomic and Precision Medicine 15 (1), e003589, 2022 | 25 | 2022 |
EMF protects cardiomyocytes against hypoxia-induced injury via heat shock protein 70 activation J Wei, J Tong, L Yu, J Zhang Chemico-biological interactions 248, 8-17, 2016 | 21 | 2016 |
Limiting RyR2 open time prevents Alzheimer's disease‐related deficits in the 3xTG‐AD mouse model Y Liu, J Yao, Z Song, W Guo, B Sun, J Wei, JP Estillore, TG Back, ... Journal of Neuroscience Research 99 (11), 2906-2921, 2021 | 19 | 2021 |
CPVT-associated cardiac ryanodine receptor mutation G357S with reduced penetrance impairs Ca2+ release termination and diminishes protein expression Y Liu, J Wei, SM Wong King Yuen, B Sun, Y Tang, R Wang, ... PLoS One 12 (9), e0184177, 2017 | 19 | 2017 |
Role of cardiac ryanodine receptor calmodulin‐binding domains in mediating the action of arrhythmogenic calmodulin N‐domain mutation N54I MT Søndergaard, Y Liu, W Guo, J Wei, R Wang, M Brohus, MT Overgaard, ... The FEBS Journal 287 (11), 2256-2280, 2020 | 17 | 2020 |
Reduced expression of cardiac ryanodine receptor protects against stress-induced ventricular tachyarrhythmia, but increases the susceptibility to cardiac alternans X Zhong, A Vallmitjana, B Sun, Z Xiao, W Guo, J Wei, M Ni, Y Chen, ... Biochemical Journal 475 (1), 169-183, 2018 | 16 | 2018 |
Nebivolol suppresses cardiac ryanodine receptor-mediated spontaneous Ca2+ release and catecholaminergic polymorphic ventricular tachycardia Z Tan, Z Xiao, J Wei, J Zhang, Q Zhou, CD Smith, A Nani, G Wu, LS Song, ... Biochemical Journal 473 (22), 4159-4172, 2016 | 16 | 2016 |