| The regulated assembly of a PKCϵ complex controls the completion of cytokinesis AT Saurin, J Durgan, AJ Cameron, A Faisal, MS Marber, PJ Parker Nature cell biology 10 (8), 891-901, 2008 | 157 | 2008 |
| Isoform-specific knockdown and expression of adaptor protein ShcA using small interfering RNA M Kisielow, S Kleiner, M Nagasawa, A Faisal, Y Nagamine Biochemical Journal 363 (1), 1-5, 2002 | 154 | 2002 |
| Selective FLT3 inhibition of FLT3-ITD+ acute myeloid leukaemia resulting in secondary D835Y mutation: a model for emerging clinical resistance patterns AS Moore, A Faisal, DG De Castro, V Bavetsias, C Sun, B Atrash, ... Leukemia 26 (7), 1462-1470, 2012 | 141 | 2012 |
| p66shc inhibits pro-survival epidermal growth factor receptor/ERK signaling during severe oxidative stress in mouse renal proximal tubule cells I Arany, A Faisal, Y Nagamine, RL Safirstein Journal of biological chemistry 283 (10), 6110-6117, 2008 | 110 | 2008 |
| Imidazo[4,5-b]pyridine Derivatives As Inhibitors of Aurora Kinases: Lead Optimization Studies toward the Identification of an Orally Bioavailable Preclinical … V Bavetsias, JM Large, C Sun, N Bouloc, M Kosmopoulou, M Matteucci, ... Journal of medicinal chemistry 53 (14), 5213-5228, 2010 | 103 | 2010 |
| The Aurora Kinase Inhibitor CCT137690 Downregulates MYCN and Sensitizes MYCN-Amplified Neuroblastoma In Vivo A Faisal, L Vaughan, V Bavetsias, C Sun, B Atrash, S Avery, Y Jamin, ... Molecular cancer therapeutics 10 (11), 2115-2123, 2011 | 98 | 2011 |
| Structure-Based Design of Orally Bioavailable 1H-Pyrrolo[3,2-c]pyridine Inhibitors of Mitotic Kinase Monopolar Spindle 1 (MPS1) S Naud, IM Westwood, A Faisal, P Sheldrake, V Bavetsias, B Atrash, ... Journal of medicinal chemistry 56 (24), 10045-10065, 2013 | 84 | 2013 |
| Optimization of Imidazo[4,5-b]pyridine-Based Kinase Inhibitors: Identification of a Dual FLT3/Aurora Kinase Inhibitor as an Orally Bioavailable Preclinical … V Bavetsias, S Crumpler, C Sun, S Avery, B Atrash, A Faisal, AS Moore, ... Journal of medicinal chemistry 55 (20), 8721-8734, 2012 | 83 | 2012 |
| Aurora Isoform Selectivity: Design and Synthesis of Imidazo[4,5-b]pyridine Derivatives as Highly Selective Inhibitors of Aurora-A Kinase in Cells V Bavetsias, A Faisal, S Crumpler, N Brown, M Kosmopoulou, A Joshi, ... Journal of Medicinal Chemistry 56 (22), 9122-9135, 2013 | 75 | 2013 |
| Serine/threonine phosphorylation of ShcA: Regulation of protein-tyrosine phosphatase-pest binding and involvement in insulin signaling A Faisal, M El-Shemerly, D Hess, Y Nagamine Journal of Biological Chemistry 277 (33), 30144-30152, 2002 | 68 | 2002 |
| Development of antibodies against in-vitro expressed coat Protein and replication associated protein of cotton leaf curl virus M Saeed, A Bashir, A Faisal, N Ahmad, Z Qamar, KA Malik, Y Zafar Submitted to Microbiology & Immunology, Japan, 2002 | 65 | 2002 |
| p66SHC-mediated mitochondrial dysfunction in renal proximal tubule cells during oxidative injury I Arany, A Faisal, JS Clark, T Vera, R Baliga, Y Nagamine American Journal of Physiology-Renal Physiology 298 (5), F1214-F1221, 2010 | 64 | 2010 |
| The scaffold MyD88 acts to couple protein kinase Cϵ to Toll-like receptors A Faisal, A Saurin, B Gregory, B Foxwell, PJ Parker Journal of biological chemistry 283 (27), 18591-18600, 2008 | 63 | 2008 |
| Cisplatin induces apoptosis through the ERK–p66shc pathway in renal proximal tubule cells JS Clark, A Faisal, R Baliga, Y Nagamine, I Arany Cancer letters 297 (2), 165-170, 2010 | 58 | 2010 |
| A cancer-associated aurora A mutant is mislocalized and misregulated due to loss of interaction with TPX2 RA Bibby, C Tang, A Faisal, K Drosopoulos, S Lubbe, R Houlston, ... Journal of biological chemistry 284 (48), 33177-33184, 2009 | 55 | 2009 |
| Protein kinases, from B to C AJ Cameron, M De Rycker, V Calleja, D Alcor, S Kjaer, B Kostelecky, ... Biochemical Society Transactions 35 (5), 1013-1017, 2007 | 46 | 2007 |
| Structure-based design of imidazo [1, 2-a] pyrazine derivatives as selective inhibitors of Aurora-A kinase in cells N Bouloc, JM Large, M Kosmopoulou, C Sun, A Faisal, M Matteucci, ... Bioorganic & medicinal chemistry letters 20 (20), 5988-5993, 2010 | 45 | 2010 |
| Colon specific enzyme responsive oligoester crosslinked dextran nanoparticles for controlled release of 5-fluorouracil M Abid, M Naveed, I Azeem, A Faisal, MF Nazar, B Yameen International Journal of Pharmaceutics 586, 119605, 2020 | 41 | 2020 |
| Hydrothermal synthesis of carbon nanodots from bovine gelatin and PHM3 microalgae strain for anticancer and bioimaging applications M Amjad, M Iqbal, A Faisal, AM Junjua, I Hussain, SZ Hussain, ... Nanoscale Advances 1 (8), 2924-2936, 2019 | 40 | 2019 |
| Synthesis and evaluation of novel α-substituted chalcones with potent anti-cancer activities and ability to overcome multidrug resistance S Riaz, M Iqbal, R Ullah, R Zahra, GA Chotana, A Faisal, RSZ Saleem Bioorganic Chemistry 87, 123-135, 2019 | 39 | 2019 |
