Single-cell RNA-seq reveals ectopic and aberrant lung-resident cell populations in idiopathic pulmonary fibrosis TS Adams, JC Schupp, S Poli, EA Ayaub, N Neumark, F Ahangari, ... Science advances 6 (28), eaba1983, 2020 | 1007 | 2020 |
Integrated single-cell atlas of endothelial cells of the human lung JC Schupp, TS Adams, C Cosme Jr, MSB Raredon, Y Yuan, N Omote, ... Circulation 144 (4), 286-302, 2021 | 278 | 2021 |
Immune dysregulation and autoreactivity correlate with disease severity in SARS-CoV-2-associated multisystem inflammatory syndrome in children A Ramaswamy, NN Brodsky, TS Sumida, M Comi, H Asashima, ... Immunity 54 (5), 1083-1095. e7, 2021 | 240 | 2021 |
Polysomnographic phenotypes and their cardiovascular implications in obstructive sleep apnoea AV Zinchuk, S Jeon, BB Koo, X Yan, DM Bravata, L Qin, BJ Selim, ... Thorax 73 (5), 472-480, 2018 | 234 | 2018 |
T cell-intrinsic role of IL-6 signaling in primary and memory responses SA Nish, D Schenten, FT Wunderlich, SD Pope, Y Gao, N Hoshi, S Yu, ... elife 3, e01949, 2014 | 182 | 2014 |
Genomic androgen receptor-occupied regions with different functions, defined by histone acetylation, coregulators and transcriptional capacity LI Jia, BP Berman, U Jariwala, X Yan, JP Cogan, A Walters, T Chen, ... PloS one 3 (11), e3645, 2008 | 177 | 2008 |
Single-cell multi-omics reveals dyssynchrony of the innate and adaptive immune system in progressive COVID-19 A Unterman, TS Sumida, N Nouri, X Yan, AY Zhao, V Gasque, JC Schupp, ... Nature communications 13 (1), 440, 2022 | 157 | 2022 |
Validation of a 52-gene risk profile for outcome prediction in patients with idiopathic pulmonary fibrosis: an international, multicentre, cohort study JD Herazo-Maya, J Sun, PL Molyneaux, Q Li, JA Villalba, A Tzouvelekis, ... The Lancet Respiratory Medicine 5 (11), 857-868, 2017 | 151 | 2017 |
Transcriptional regulatory model of fibrosis progression in the human lung JE McDonough, F Ahangari, Q Li, S Jain, SE Verleden, J Herazo-Maya, ... JCI insight 4 (22), 2019 | 148 | 2019 |
Signaling through the adaptor molecule MyD88 in CD4+ T cells is required to overcome suppression by regulatory T cells D Schenten, SA Nish, S Yu, X Yan, HK Lee, I Brodsky, L Pasman, B Yordy, ... Immunity 40 (1), 78-90, 2014 | 142 | 2014 |
An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge CA Brownstein, AH Beggs, N Homer, B Merriman, TW Yu, KC Flannery, ... Genome biology 15, 1-18, 2014 | 126 | 2014 |
Noninvasive analysis of the sputum transcriptome discriminates clinical phenotypes of asthma X Yan, JH Chu, J Gomez, M Koenigs, C Holm, X He, MF Perez, H Zhao, ... American journal of respiratory and critical care medicine 191 (10), 1116-1125, 2015 | 96 | 2015 |
Inferring activity changes of transcription factors by binding association with sorted expression profiles C Cheng, X Yan, F Sun, LM Li BMC bioinformatics 8 (1), 452, 2007 | 90 | 2007 |
Single-cell transcriptional archetypes of airway inflammation in cystic fibrosis JC Schupp, S Khanal, JL Gomez, M Sauler, TS Adams, GL Chupp, X Yan, ... American journal of respiratory and critical care medicine 202 (10), 1419-1429, 2020 | 74 | 2020 |
Severe respiratory viral infection induces procalcitonin in the absence of bacterial pneumonia S Gautam, AJ Cohen, Y Stahl, PV Toro, GM Young, R Datta, X Yan, ... Thorax 75 (11), 974-981, 2020 | 73 | 2020 |
A network of sputum microRNAs is associated with neutrophilic airway inflammation in asthma JL Gomez, A Chen, MP Diaz, N Zirn, A Gupta, C Britto, M Sauler, X Yan, ... American journal of respiratory and critical care medicine 202 (1), 51-64, 2020 | 65 | 2020 |
Identification and validation of differentially expressed transcripts by RNA-sequencing of formalin-fixed, paraffin-embedded (FFPE) lung tissue from patients with Idiopathic … M Vukmirovic, JD Herazo-Maya, J Blackmon, V Skodric-Trifunovic, ... BMC Pulmonary Medicine 17, 1-12, 2017 | 61 | 2017 |
Characterisation of asthma subgroups associated with circulating YKL-40 levels JL Gomez, X Yan, CT Holm, N Grant, Q Liu, L Cohn, V Nezgovorova, ... European Respiratory Journal 50 (4), 2017 | 61 | 2017 |
Detecting differentially expressed genes by relative entropy X Yan, M Deng, WK Fung, M Qian Journal of theoretical biology 234 (3), 395-402, 2005 | 47 | 2005 |
Transcriptomics of bronchoalveolar lavage cells identifies new molecular endotypes of sarcoidosis M Vukmirovic, X Yan, KF Gibson, M Gulati, JC Schupp, G DeIuliis, ... European Respiratory Journal 58 (6), 2021 | 42 | 2021 |