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Adam Mead
Adam Mead
Verified email at imm.ox.ac.uk - Homepage
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The impact of FLT3 internal tandem duplication mutant level, number, size, and interaction with NPM1 mutations in a large cohort of young adult patients with acute …
RE Gale, C Green, C Allen, AJ Mead, AK Burnett, RK Hills, DC Linch
Blood, The Journal of the American Society of Hematology 111 (5), 2776-2784, 2008
9572008
Coexistence of LMPP-like and GMP-like leukemia stem cells in acute myeloid leukemia
N Goardon, E Marchi, A Atzberger, L Quek, A Schuh, S Soneji, P Woll, ...
Cancer cell 19 (1), 138-152, 2011
7442011
Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy
A Sanjuan-Pla, IC Macaulay, CT Jensen, PS Woll, TC Luis, A Mead, ...
Nature 502 (7470), 232-236, 2013
6972013
FLT3 tyrosine kinase domain mutations are biologically distinct from and have a significantly more favorable prognosis than FLT3 internal tandem duplications in patients with …
AJ Mead, DC Linch, RK Hills, K Wheatley, AK Burnett, RE Gale
Blood, The Journal of the American Society of Hematology 110 (4), 1262-1270, 2007
4132007
Whole-genome sequencing of patients with rare diseases in a national health system
E Turro, WJ Astle, K Megy, S Gräf, D Greene, O Shamardina, HL Allen, ...
Nature 583 (7814), 96-102, 2020
4092020
Single-cell transcriptomics uncovers distinct molecular signatures of stem cells in chronic myeloid leukemia
A Giustacchini, S Thongjuea, N Barkas, PS Woll, BJ Povinelli, CAG Booth, ...
Nature medicine 23 (6), 692-702, 2017
4072017
Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo
PS Woll, U Kjällquist, O Chowdhury, H Doolittle, DC Wedge, S Thongjuea, ...
Cancer cell 25 (6), 794-808, 2014
3612014
Persistent malignant stem cells in del (5q) myelodysplasia in remission
R Tehranchi, PS Woll, K Anderson, N Buza-Vidas, T Mizukami, AJ Mead, ...
New England Journal of Medicine 363 (11), 1025-1037, 2010
3252010
Single-cell RNA sequencing reveals molecular and functional platelet bias of aged haematopoietic stem cells
A Grover, A Sanjuan-Pla, S Thongjuea, J Carrelha, A Giustacchini, ...
Nature communications 7 (1), 11075, 2016
2972016
Lymphomyeloid contribution of an immune-restricted progenitor emerging prior to definitive hematopoietic stem cells
C Böiers, J Carrelha, M Lutteropp, S Luc, JCA Green, E Azzoni, PS Woll, ...
Cell stem cell 13 (5), 535-548, 2013
2962013
Pacritinib versus best available therapy for the treatment of myelofibrosis irrespective of baseline cytopenias (PERSIST-1): an international, randomised, phase 3 trial
RA Mesa, AM Vannucchi, A Mead, M Egyed, A Szoke, A Suvorov, ...
The Lancet Haematology 4 (5), e225-e236, 2017
2862017
Unravelling intratumoral heterogeneity through high-sensitivity single-cell mutational analysis and parallel RNA sequencing
A Rodriguez-Meira, G Buck, SA Clark, BJ Povinelli, V Alcolea, E Louka, ...
Molecular cell 73 (6), 1292-1305. e8, 2019
2592019
Distinct myeloid progenitor–differentiation pathways identified through single-cell RNA sequencing
R Drissen, N Buza-Vidas, P Woll, S Thongjuea, A Gambardella, ...
Nature immunology 17 (6), 666-676, 2016
2462016
Germline selection shapes human mitochondrial DNA diversity
W Wei, S Tuna, MJ Keogh, KR Smith, TJ Aitman, PL Beales, DL Bennett, ...
Science 364 (6442), eaau6520, 2019
1892019
Genetic variation at MECOM, TERT, JAK2 and HBS1L-MYB predisposes to myeloproliferative neoplasms
W Tapper, AV Jones, R Kralovics, AS Harutyunyan, K Zoi, W Leung, ...
Nature communications 6 (1), 6691, 2015
1872015
Myeloproliferative neoplasm stem cells
AJ Mead, A Mullally
Blood, The Journal of the American Society of Hematology 129 (12), 1607-1616, 2017
1772017
Whole-genome sequencing of a sporadic primary immunodeficiency cohort
JED Thaventhiran, H Lango Allen, OS Burren, W Rae, D Greene, ...
Nature 583 (7814), 90-95, 2020
1732020
The earliest thymic T cell progenitors sustain B cell and myeloid lineage potential
S Luc, TC Luis, H Boukarabila, IC Macaulay, N Buza-Vidas, ...
Nature immunology 13 (4), 412-419, 2012
1712012
Guideline for the investigation and management of eosinophilia
N Butt, J Lambert, S Ali, P Beer, N Cross, A Duncombe, J Ewing, ...
British journal of haematology 176 (4), 2017
1652017
Genetically distinct leukemic stem cells in human CD34 acute myeloid leukemia are arrested at a hemopoietic precursor-like stage
L Quek, GW Otto, C Garnett, L Lhermitte, D Karamitros, B Stoilova, IJ Lau, ...
Journal of Experimental Medicine 213 (8), 1513-1535, 2016
1652016
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