Eva Frickel
Eva Frickel
Host-Toxoplasma Interaction Laboratory, University of Birmingham
Verified email at - Homepage
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CD8α+ dendritic cells are the critical source of interleukin-12 that controls acute infection by Toxoplasma gondii tachyzoites
M Mashayekhi, MM Sandau, IR Dunay, EM Frickel, A Khan, ...
Immunity 35 (2), 249-259, 2011
TROSY-NMR reveals interaction between ERp57 and the tip of the calreticulin P-domain
EM Frickel, R Riek, I Jelesarov, A Helenius, K Wüthrich, L Ellgaard
Proceedings of the National Academy of Sciences 99 (4), 1954-1959, 2002
ERp57 is a multifunctional thiol-disulfide oxidoreductase
EM Frickel, P Frei, M Bouvier, WF Stafford, A Helenius, R Glockshuber, ...
Journal of Biological Chemistry 279 (18), 18277-18287, 2004
Calnexin, calreticulin, and ERp57
L Ellgaard, EM Frickel
Cell biochemistry and biophysics 39 (3), 223-247, 2003
IRG and GBP host resistance factors target aberrant,“non-self” vacuoles characterized by the missing of “self” IRGM proteins
AK Haldar, HA Saka, AS Piro, JD Dunn, SC Henry, GA Taylor, EM Frickel, ...
PLoS pathogens 9 (6), e1003414, 2013
Ubiquitin systems mark pathogen-containing vacuoles as targets for host defense by guanylate binding proteins
AK Haldar, C Foltz, R Finethy, AS Piro, EM Feeley, DM Pilla-Moffett, ...
Proceedings of the National Academy of Sciences 112 (41), E5628-E5637, 2015
Determinants of GBP Recruitment to Toxoplasma gondii Vacuoles and the Parasitic Factors That Control It
S Virreira Winter, W Niedelman, KD Jensen, EE Rosowski, L Julien, ...
PloS one 6 (9), e24434, 2011
Parasite Stage-Specific Recognition of Endogenous Toxoplasma gondii-Derived CD8+ T Cell Epitopes
EM Frickel, N Sahoo, J Hopp, MJ Gubbels, MPJ Craver, LJ Knoll, ...
The Journal of infectious diseases 198 (11), 1625-1633, 2008
Human GBP 1 is a microbe‐specific gatekeeper of macrophage apoptosis and pyroptosis
D Fisch, H Bando, B Clough, V Hornung, M Yamamoto, AR Shenoy, ...
The EMBO journal 38 (13), e100926, 2019
Differential Regulation of Effector- and Central-Memory Responses to Toxoplasma gondii Infection by IL-12 Revealed by Tracking of Tgd057-Specific CD8+ T Cells
DC Wilson, GM Grotenbreg, K Liu, Y Zhao, EM Frickel, MJ Gubbels, ...
PLoS pathogens 6 (3), e1000815, 2010
The Toxoplasma parasitophorous vacuole: an evolving host–parasite frontier
B Clough, EM Frickel
Trends in parasitology 33 (6), 473-488, 2017
Domain Architecture of Protein-disulfide Isomerase Facilitates Its Dual Role as an Oxidase and an Isomerase in Ero1p-mediated Disulfide Formation*♦
MS Kulp, EM Frickel, L Ellgaard, JS Weissman
Journal of Biological Chemistry 281 (2), 876-884, 2006
Apicomplexan UCHL3 retains dual specificity for ubiquitin and Nedd8 throughout evolution
EM Frickel, V Quesada, L Muething, MJ Gubbels, E Spooner, H Ploegh, ...
Cellular microbiology 9 (6), 1601-1610, 2007
Detection of Cytosolic Shigella flexneri via a C-Terminal Triple-Arginine Motif of GBP1 Inhibits Actin-Based Motility
AS Piro, D Hernandez, S Luoma, EM Feeley, R Finethy, A Yirga, ...
MBio 8 (6), e01979-17, 2017
Yeast glyoxalase I is a monomeric enzyme with two active sites
EM Frickel, P Jemth, M Widersten, B Mannervik
Journal of Biological Chemistry 276 (3), 1845-1849, 2001
Cell death of gamma interferon-stimulated human fibroblasts upon Toxoplasma gondii infection induces early parasite egress and limits parasite replication
W Niedelman, JK Sprokholt, B Clough, EM Frickel, JPJ Saeij
Infection and immunity 81 (12), 4341-4349, 2013
Transnuclear mice with predefined T cell receptor specificities against Toxoplasma gondii obtained via SCNT
O Kirak, EM Frickel, GM Grotenbreg, H Suh, R Jaenisch, HL Ploegh
Science 328 (5975), 243-248, 2010
K63-Linked Ubiquitination Targets Toxoplasma gondii for Endo-lysosomal Destruction in IFNγ-Stimulated Human Cells
B Clough, JD Wright, PM Pereira, EM Hirst, AC Johnston, R Henriques, ...
PLoS pathogens 12 (11), e1006027, 2016
Human GBP1 does not localize to pathogen vacuoles but restricts Toxoplasma gondii
AC Johnston, A Piro, B Clough, M Siew, S Virreira Winter, J Coers, ...
Cellular microbiology 18 (8), 1056-1064, 2016
Toxoplasma gondii Superinfection and Virulence during Secondary Infection Correlate with the Exact ROP5/ROP18 Allelic Combination
KDC Jensen, A Camejo, MB Melo, C Cordeiro, L Julien, GM Grotenbreg, ...
MBio 6 (2), e02280-14, 2015
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