Clusters of hyperactive neurons near amyloid plaques in a mouse model of Alzheimer's disease MA Busche, G Eichhoff, H Adelsberger, D Abramowski, KH Wiederhold, ... Science 321 (5896), 1686-1689, 2008 | 1163 | 2008 |
Synergy between amyloid-β and tau in Alzheimer’s disease MA Busche, BT Hyman Nature neuroscience 23 (10), 1183-1193, 2020 | 954 | 2020 |
Critical role of soluble amyloid-β for early hippocampal hyperactivity in a mouse model of Alzheimer’s disease MA Busche, X Chen, HA Henning, J Reichwald, M Staufenbiel, ... Proceedings of the National Academy of Sciences 109 (22), 8740-8745, 2012 | 739 | 2012 |
Tau impairs neural circuits, dominating amyloid-β effects, in Alzheimer models in vivo MA Busche, S Wegmann, S Dujardin, C Commins, J Schiantarelli, ... Nature neuroscience 22 (1), 57-64, 2019 | 402 | 2019 |
Impairments of neural circuit function in Alzheimer's disease MA Busche, A Konnerth Philosophical Transactions of the Royal Society B: Biological Sciences 371 …, 2016 | 348 | 2016 |
Neuronal hyperactivity–A key defect in Alzheimer's disease? MA Busche, A Konnerth Bioessays 37 (6), 624-632, 2015 | 242 | 2015 |
Rescue of long-range circuit dysfunction in Alzheimer's disease models MA Busche, M Kekuš, H Adelsberger, T Noda, H Förstl, I Nelken, ... Nature neuroscience 18 (11), 1623-1630, 2015 | 239 | 2015 |
What happens with the circuit in Alzheimer's disease in mice and humans? B Zott, MA Busche, RA Sperling, A Konnerth Annual review of neuroscience 41 (1), 277-297, 2018 | 209 | 2018 |
Neuronal excitation/inhibition imbalance: core element of a translational perspective on Alzheimer pathophysiology F Maestú, W de Haan, MA Busche, J DeFelipe Ageing Research Reviews 69, 101372, 2021 | 166 | 2021 |
Decreased amyloid-β and increased neuronal hyperactivity by immunotherapy in Alzheimer's models MA Busche, C Grienberger, AD Keskin, B Song, U Neumann, ... Nature neuroscience 18 (12), 1725-1727, 2015 | 166 | 2015 |
Tipping the scales: peptide-dependent dysregulation of neural circuit dynamics in Alzheimer’s disease SS Harris, F Wolf, B De Strooper, MA Busche Neuron 107 (3), 417-435, 2020 | 131 | 2020 |
BACE inhibition-dependent repair of Alzheimer’s pathophysiology AD Keskin, M Kekuš, H Adelsberger, U Neumann, DR Shimshek, B Song, ... Proceedings of the National Academy of Sciences 114 (32), 8631-8636, 2017 | 125 | 2017 |
In vivo calcium imaging of the aging and diseased brain G Eichhoff, MA Busche, O Garaschuk European journal of nuclear medicine and molecular imaging 35, 99-106, 2008 | 70 | 2008 |
Seizure protein 6 controls glycosylation and trafficking of kainate receptor subunits GluK2 and GluK3 M Pigoni, HE Hsia, J Hartmann, J Rudan Njavro, MD Shmueli, SA Müller, ... The EMBO journal 39 (15), e103457, 2020 | 28 | 2020 |
Wie Schlaf und Alzheimer-Krankheit zusammenhängen MA Busche, M Kekuš, H Förstl Der Nervenarzt 88 (3), 215-221, 2017 | 26* | 2017 |
In vivo two-photon calcium imaging of hippocampal neurons in Alzheimer mouse models MA Busche Biomarkers for Alzheimer’s Disease Drug Development, 341-351, 2018 | 24 | 2018 |
Aη-α and Aη-β peptides impair LTP ex vivo within the low nanomolar range and impact neuronal activity in vivo M Mensch, J Dunot, SM Yishan, SS Harris, A Blistein, A Avdiu, ... Alzheimer's research & therapy 13, 1-13, 2021 | 13 | 2021 |
Tau suppresses neuronal activity in vivo, even before tangles form MA Busche Brain 142 (4), 843-846, 2019 | 11 | 2019 |
Selective suppression of oligodendrocyte-derived amyloid beta rescues neuronal dysfunction in Alzheimer’s disease RM Rajani, R Ellingford, M Hellmuth, SS Harris, OS Taso, D Graykowski, ... PLoS biology 22 (7), e3002727, 2024 | 10 | 2024 |
PolyGR and polyPR knock-in mice reveal a conserved neuroprotective extracellular matrix signature in C9orf72 ALS/FTD neurons C Milioto, M Carcolé, A Giblin, R Coneys, O Attrebi, M Ahmed, SS Harris, ... Nature neuroscience 27 (4), 643-655, 2024 | 10 | 2024 |