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Christopher R Pudney
Christopher R Pudney
Professor of Applied Biochemistry, University of Bath
Verified email at bath.ac.uk - Homepage
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Cited by
Year
On the temperature dependence of enzyme-catalyzed rates
VL Arcus, EJ Prentice, JK Hobbs, AJ Mulholland, MW Van der Kamp, ...
Biochemistry 55 (12), 1681-1688, 2016
2832016
Biocatalysis with thermostable enzymes: structure and properties of a thermophilic ‘ene’‐reductase related to old yellow enzyme
BV Adalbjörnsson, HS Toogood, A Fryszkowska, CR Pudney, TA Jowitt, ...
ChemBioChem 11 (2), 197-207, 2010
1332010
Fast protein motions are coupled to enzyme H-transfer reactions.
CR Pudney, A Guerriero, NJ Baxter, LO Johannissen, JP Waltho, S Hay, ...
Journal of the American Chemical Society, 2013
1002013
Evidence to support the hypothesis that promoting vibrations enhance the rate of an enzyme catalyzed H-tunneling reaction
CR Pudney, S Hay, C Levy, J Pang, MJ Sutcliffe, D Leys, NS Scrutton
Journal of the American Chemical Society 131 (47), 17072-17073, 2009
932009
Direct Analysis of Donor− Acceptor Distance and Relationship to Isotope Effects and the Force Constant for Barrier Compression in Enzymatic H-Tunneling Reactions
CR Pudney, LO Johannissen, MJ Sutcliffe, S Hay, NS Scrutton
Journal of the American Chemical Society 132 (32), 11329-11335, 2010
922010
α-Secondary isotope effects as probes of “tunneling-ready” configurations in enzymatic H-tunneling: Insight from environmentally coupled tunneling models
CR Pudney, S Hay, MJ Sutcliffe, NS Scrutton
Journal of the American Chemical Society 128 (43), 14053-14058, 2006
832006
Barrier compression enhances an enzymatic hydrogen‐transfer reaction
S Hay, CR Pudney, TA McGrory, J Pang, MJ Sutcliffe, NS Scrutton
Angewandte Chemie International Edition 48 (8), 1452-1454, 2009
692009
Coupled motions direct electrons along human microsomal P450 Chains
CR Pudney, B Khara, LO Johannissen, NS Scrutton
PLoS biology 9 (12), e1001222, 2011
642011
Mutagenesis of morphinone reductase induces multiple reactive configurations and identifies potential ambiguity in kinetic analysis of enzyme tunneling mechanisms
CR Pudney, S Hay, J Pang, C Costello, D Leys, MJ Sutcliffe, NS Scrutton
Journal of the American Chemical Society 129 (45), 13949-13956, 2007
632007
Enzyme evolution and the temperature dependence of enzyme catalysis
VL Arcus, MW Van Der Kamp, CR Pudney, AJ Mulholland
Current Opinion in Structural Biology 65, 96-101, 2020
592020
Specificity of bispecific T cell receptors and antibodies targeting peptide-HLA
CJ Holland, RM Crean, JM Pentier, B de Wet, A Lloyd, V Srikannathasan, ...
The Journal of clinical investigation 130 (5), 2673-2688, 2020
562020
The red edge excitation shift phenomenon can be used to unmask protein structural ensembles: implications for NEMO–ubiquitin interactions
DAM Catici, HE Amos, Y Yang, JMH van den Elsen, CR Pudney
The FEBS journal 283 (12), 2272-2284, 2016
552016
A complete thermodynamic analysis of enzyme turnover links the free energy landscape to enzyme catalysis
HBL Jones, SA Wells, EJ Prentice, A Kwok, LL Liang, VL Arcus, ...
The FEBS journal 284 (17), 2829-2842, 2017
462017
Gating mechanisms for biological electron transfer: Integrating structure with biophysics reveals the nature of redox control in cytochrome P450 reductase and copper-dependent …
NGH Leferink, CR Pudney, S Brenner, DJ Heyes, RR Eady, ...
FEBS letters, 2012
422012
Are environmentally coupled enzymatic hydrogen tunneling reactions influenced by changes in solution viscosity?
S Hay, CR Pudney, MJ Sutcliffe, NS Scrutton
Angewandte Chemie 120 (3), 547-550, 2008
382008
Structural and mechanistic aspects of flavoproteins: probes of hydrogen tunnelling
S Hay, CR Pudney, NS Scrutton
The FEBS Journal 276 (15), 3930-3941, 2009
362009
Polyubiquitin drives the molecular interactions of the NF-κB essential modulator (NEMO) by allosteric regulation
DAM Catici, JE Horne, GE Cooper, CR Pudney
Journal of Biological Chemistry 290 (22), 14130-14139, 2015
322015
Bipartite recognition and conformational sampling mechanisms for hydride transfer from nicotinamide coenzyme to FMN in pentaerythritol tetranitrate reductase
CR Pudney, S Hay, NS Scrutton
The FEBS Journal 276 (17), 4780-4789, 2009
302009
Change in heat capacity accurately predicts vibrational coupling in enzyme catalyzed reactions
VL Arcus, CR Pudney
FEBS Letters, 2015
292015
Sensing enzyme activation heat capacity at the single-molecule level using gold-nanorod-based optical whispering gallery modes
S Subramanian, HBL Jones, S Frustaci, S Winter, MW van der Kamp, ...
ACS applied nano materials 4 (5), 4576-4583, 2021
282021
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