Maurizio Recanatini
Maurizio Recanatini
Professor of Medicinal Chemistry, University of Bologna
Verified email at unibo.it - Homepage
TitleCited byYear
Multi-target-directed ligands to combat neurodegenerative diseases
A Cavalli, ML Bolognesi, A Minarini, M Rosini, V Tumiatti, M Recanatini, ...
Journal of medicinal chemistry 51 (3), 347-372, 2008
7872008
Toward a pharmacophore for drugs inducing the long QT syndrome: insights from a CoMFA study of HERG K+ channel blockers
A Cavalli, E Poluzzi, F De Ponti, M Recanatini
Journal of medicinal chemistry 45 (18), 3844-3853, 2002
3752002
Safety of non-antiarrhythmic drugs that prolong the QT interval or induce torsade de pointes
F De Ponti, E Poluzzi, A Cavalli, M Recanatini, N Montanaro
Drug safety 25 (4), 263-286, 2002
3362002
QT prolongation through hERG K+ channel blockade: Current knowledge and strategies for the early prediction during drug development
M Recanatini, E Poluzzi, M Masetti, A Cavalli, F De Ponti
Medicinal research reviews 25 (2), 133-166, 2005
2502005
3-(4-{[Benzyl(methyl)amino]methyl}phenyl)-6,7-dimethoxy-2H-2-chromenone (AP2238) Inhibits Both Acetylcholinesterase and Acetylcholinesterase-Induced β …
L Piazzi, A Rampa, A Bisi, S Gobbi, F Belluti, A Cavalli, M Bartolini, ...
Journal of medicinal chemistry 46 (12), 2279-2282, 2003
2262003
Multi-target-directed drug design strategy: from a dual binding site acetylcholinesterase inhibitor to a trifunctional compound against Alzheimer’s disease
ML Bolognesi, A Cavalli, L Valgimigli, M Bartolini, M Rosini, V Andrisano, ...
Journal of medicinal chemistry 50 (26), 6446-6449, 2007
2232007
Multi-target-directed coumarin derivatives: hAChE and BACE1 inhibitors as potential anti-Alzheimer compounds
L Piazzi, A Cavalli, F Colizzi, F Belluti, M Bartolini, F Mancini, ...
Bioorganic & medicinal chemistry letters 18 (1), 423-426, 2008
1892008
A small molecule targeting the multifactorial nature of Alzheimer's disease
A Cavalli, ML Bolognesi, S Capsoni, V Andrisano, M Bartolini, E Margotti, ...
Angewandte Chemie International Edition 46 (20), 3689-3692, 2007
1832007
Single-molecule pulling simulations can discern active from inactive enzyme inhibitors
F Colizzi, R Perozzo, L Scapozza, M Recanatini, A Cavalli
Journal of the American Chemical Society 132 (21), 7361-7371, 2010
1462010
SAR of 9-amino-1, 2, 3, 4-tetrahydroacridine-based acetylcholinesterase inhibitors: synthesis, enzyme inhibitory activity, QSAR, and structure-based CoMFA of tacrine analogues
M Recanatini, A Cavalli, F Belluti, L Piazzi, A Rampa, A Bisi, S Gobbi, ...
Journal of medicinal chemistry 43 (10), 2007-2018, 2000
1452000
Determination of lipophilicity by means of reversed-phase thin-layer chromatography: I. Basic aspects and relationship between slope and intercept of TLC equations
GL Biagi, AM Barbaro, A Sapone, M Recanatini
Journal of Chromatography A 662 (2), 341-361, 1994
1391994
A new class of nonsteroidal aromatase inhibitors: design and synthesis of chromone and xanthone derivatives and inhibition of the P450 enzymes aromatase and 17α-hydroxylase/C17 …
M Recanatini, A Bisi, A Cavalli, F Belluti, S Gobbi, A Rampa, P Valenti, ...
Journal of medicinal chemistry 44 (5), 672-680, 2001
1372001
Novel class of quinone-bearing polyamines as multi-target-directed ligands to combat Alzheimer's disease
ML Bolognesi, R Banzi, M Bartolini, A Cavalli, A Tarozzi, V Andrisano, ...
Journal of medicinal chemistry 50 (20), 4882-4897, 2007
1232007
Acetylcholinesterase inhibitors for potential use in Alzheimer's disease: molecular modeling, synthesis and kinetic evaluation of 11H-indeno-[1, 2-b]-quinolin-10-ylamine …
A Rampa, A Bisi, F Belluti, S Gobbi, P Valenti, V Andrisano, V Cavrini, ...
Bioorganic & medicinal chemistry 8 (3), 497-506, 2000
1072000
Target-related applications of first principles quantum chemical methods in drug design
A Cavalli, P Carloni, M Recanatini
Chemical reviews 106 (9), 3497-3519, 2006
1062006
Protein conformational transitions: the closure mechanism of a kinase explored by atomistic simulations
A Berteotti, A Cavalli, D Branduardi, FL Gervasio, M Recanatini, ...
Journal of the American Chemical Society 131 (1), 244-250, 2008
992008
Lead optimization providing a series of flavone derivatives as potent nonsteroidal inhibitors of the cytochrome P450 aromatase enzyme
S Gobbi, A Cavalli, A Rampa, F Belluti, L Piazzi, A Paluszcak, ...
Journal of medicinal chemistry 49 (15), 4777-4780, 2006
962006
Nonsteroidal aromatase inhibitors: recent advances
M Recanatini, A Cavalli, P Valenti
Medicinal research reviews 22 (3), 282-304, 2002
942002
The role of the peripheral anionic site and cation− π interactions in the ligand penetration of the human AChE gorge
D Branduardi, FL Gervasio, A Cavalli, M Recanatini, M Parrinello
Journal of the American Chemical Society 127 (25), 9147-9155, 2005
912005
Cholinesterase inhibitors: Xanthostigmine derivatives blocking the acetylcholinesterase-induced β-amyloid aggregation
F Belluti, A Rampa, L Piazzi, A Bisi, S Gobbi, M Bartolini, V Andrisano, ...
Journal of medicinal chemistry 48 (13), 4444-4456, 2005
892005
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