| Multi-target-directed ligands to combat neurodegenerative diseases A Cavalli, ML Bolognesi, A Minarini, M Rosini, V Tumiatti, M Recanatini, ... Journal of medicinal chemistry 51 (3), 347-372, 2008 | 1361 | 2008 |
| Toward a pharmacophore for drugs inducing the long QT syndrome: insights from a CoMFA study of HERG K+ channel blockers A Cavalli, E Poluzzi, F De Ponti, M Recanatini Journal of medicinal chemistry 45 (18), 3844-3853, 2002 | 509 | 2002 |
| Safety of non-antiarrhythmic drugs that prolong the QT interval or induce torsade de pointes: an overview F De Ponti, E Poluzzi, A Cavalli, M Recanatini, N Montanaro Drug safety 25, 263-286, 2002 | 387 | 2002 |
| QT prolongation through hERG K+ channel blockade: Current knowledge and strategies for the early prediction during drug development M Recanatini, E Poluzzi, M Masetti, A Cavalli, F De Ponti Medicinal research reviews 25 (2), 133-166, 2005 | 365 | 2005 |
| 3-(4-{[Benzyl(methyl)amino]methyl}phenyl)-6,7-dimethoxy-2H-2-chromenone (AP2238) Inhibits Both Acetylcholinesterase and Acetylcholinesterase-Induced β … L Piazzi, A Rampa, A Bisi, S Gobbi, F Belluti, A Cavalli, M Bartolini, ... Journal of medicinal chemistry 46 (12), 2279-2282, 2003 | 330 | 2003 |
| Multi-target-directed drug design strategy: from a dual binding site acetylcholinesterase inhibitor to a trifunctional compound against Alzheimer’s disease ML Bolognesi, A Cavalli, L Valgimigli, M Bartolini, M Rosini, V Andrisano, ... Journal of medicinal chemistry 50 (26), 6446-6449, 2007 | 326 | 2007 |
| Multi-target-directed coumarin derivatives: hAChE and BACE1 inhibitors as potential anti-Alzheimer compounds L Piazzi, A Cavalli, F Colizzi, F Belluti, M Bartolini, F Mancini, ... Bioorganic & Medicinal Chemistry Letters 18 (1), 423-426, 2008 | 307 | 2008 |
| A small molecule targeting the multifactorial nature of Alzheimer's disease A Cavalli, ML Bolognesi, S Capsoni, V Andrisano, M Bartolini, E Margotti, ... ANGEWANDTE CHEMIE. INTERNATIONAL EDITION 46, 3689-3692, 2007 | 241 | 2007 |
| SAR of 9-amino-1, 2, 3, 4-tetrahydroacridine-based acetylcholinesterase inhibitors: synthesis, enzyme inhibitory activity, QSAR, and structure-based CoMFA of tacrine analogues M Recanatini, A Cavalli, F Belluti, L Piazzi, A Rampa, A Bisi, S Gobbi, ... Journal of medicinal chemistry 43 (10), 2007-2018, 2000 | 224 | 2000 |
| Single-molecule pulling simulations can discern active from inactive enzyme inhibitors F Colizzi, R Perozzo, L Scapozza, M Recanatini, A Cavalli Journal of the American Chemical Society 132 (21), 7361-7371, 2010 | 211 | 2010 |
| Galloflavin (CAS 568‐80‐9): a novel inhibitor of lactate dehydrogenase M Manerba, M Vettraino, L Fiume, G Di Stefano, A Sartini, E Giacomini, ... ChemMedChem 7 (2), 311-317, 2012 | 199 | 2012 |
| Phytoestrogens in postmenopause: the state of the art from a chemical, pharmacological and regulatory perspective E Poluzzi, C Piccinni, E Raschi, A Rampa, M Recanatini, F De Ponti Current medicinal chemistry 21 (4), 417-436, 2014 | 194 | 2014 |
| Dynamic docking: a paradigm shift in computational drug discovery D Gioia, M Bertazzo, M Recanatini, M Masetti, A Cavalli Molecules 22 (11), 2029, 2017 | 183 | 2017 |
| A new class of nonsteroidal aromatase inhibitors: design and synthesis of chromone and xanthone derivatives and inhibition of the P450 enzymes aromatase and 17α-hydroxylase/C17 … M Recanatini, A Bisi, A Cavalli, F Belluti, S Gobbi, A Rampa, P Valenti, ... Journal of medicinal chemistry 44 (5), 672-680, 2001 | 182 | 2001 |
| Novel class of quinone-bearing polyamines as multi-target-directed ligands to combat Alzheimer's disease ML Bolognesi, R Banzi, M Bartolini, A Cavalli, A Tarozzi, V Andrisano, ... Journal of medicinal chemistry 50 (20), 4882-4897, 2007 | 178 | 2007 |
| Determination of lipophilicity by means of reversed-phase thin-layer chromatography: I. Basic aspects and relationship between slope and intercept of TLC equations GL Biagi, AM Barbaro, A Sapone, M Recanatini Journal of Chromatography A 662 (2), 341-361, 1994 | 175 | 1994 |
| Protein conformational transitions: the closure mechanism of a kinase explored by atomistic simulations A Berteotti, A Cavalli, D Branduardi, FL Gervasio, M Recanatini, ... Journal of the American Chemical Society 131 (1), 244-250, 2009 | 155 | 2009 |
| The role of fragment-based and computational methods in polypharmacology G Bottegoni, AD Favia, M Recanatini, A Cavalli Drug discovery today 17 (1-2), 23-34, 2012 | 151 | 2012 |
| Target-related applications of first principles quantum chemical methods in drug design A Cavalli, P Carloni, M Recanatini Chemical reviews 106 (9), 3497-3519, 2006 | 146 | 2006 |
| The role of the peripheral anionic site and cation− π interactions in the ligand penetration of the human AChE gorge D Branduardi, FL Gervasio, A Cavalli, M Recanatini, M Parrinello Journal of the American Chemical Society 127 (25), 9147-9155, 2005 | 139 | 2005 |
Andrea CavalliDirector, CECAM-EPFL - Professor, University of BolognaVerified email at unibo.it
