Patrick Maurel
Patrick Maurel
Inserm, Montpellier France
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TitleCited byYear
Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression
P Kuehl, J Zhang, Y Lin, J Lamba, M Assem, J Schuetz, PB Watkins, ...
Nature genetics 27 (4), 383-391, 2001
Primary hepatocytes: current understanding of the regulation of metabolic enzymes and transporter proteins, and pharmaceutical practice for the use of hepatocytes in metabolism …
NJ Hewitt, MJ Gómez Lechón, JB Houston, D Hallifax, HS Brown, ...
Drug metabolism reviews 39 (1), 159-234, 2007
Cyclosporin A drug interactions. Screening for inducers and inhibitors of cytochrome P-450 (cyclosporin A oxidase) in primary cultures of human hepatocytes and in liver microsomes.
L Pichard, I Fabre, G Fabre, J Domergue, B Saint Aubert, G Mourad, ...
Drug Metabolism and Disposition 18 (5), 595-606, 1990
Identification of an inducible form of cytochrome P-450 in human liver
PB Watkins, SA Wrighton, P Maurel, EG Schuetz, G Mendez-Picon, ...
Proceedings of the National Academy of Sciences 82 (18), 6310-6314, 1985
The increase in urinary excretion of 6 beta‐hydroxycortisol as a marker of human hepatic cytochrome P450IIIA induction.
C Ged, JM Rouillon, L Pichard, J Combalbert, N Bressot, P Bories, ...
British journal of clinical pharmacology 28 (4), 373-387, 1989
Expression of cyp3a4, cyp2b6, andcyp2c9 is regulated by the vitamin d receptor pathway in primary human hepatocytes
L Drocourt, JC Ourlin, JM Pascussi, P Maurel, MJ Vilarem
Journal of Biological Chemistry 277 (28), 25125-25132, 2002
Induction of CYP2C genes in human hepatocytes in primary culture
S Gerbal-Chaloin, JM Pascussi, L Pichard-Garcia, M Daujat, F Waechter, ...
Drug Metabolism and Disposition 29 (3), 242-251, 2001
The expression of CYP2B6, CYP2C9 and CYP3A4 genes: a tangle of networks of nuclear and steroid receptors
JM Pascussi, S Gerbal-Chaloin, L Drocourt, P Maurel, MJ Vilarem
Biochimica et Biophysica Acta (BBA)-General Subjects 1619 (3), 243-253, 2003
Dexamethasone induces pregnane X receptor and retinoid X receptor-α expression in human hepatocytes: synergistic increase of CYP3A4 induction by pregnane X receptor activators
JM Pascussi, L Drocourt, JM Fabre, P Maurel, MJ Vilarem
Molecular pharmacology 58 (2), 361-372, 2000
Metabolism of cyclosporin A. IV. Purification and identification of the rifampicin-inducible human liver cytochrome P-450 (cyclosporin A oxidase) as a product of P450IIIA gene …
J Combalbert, I Fabre, G Fabre, I Dalet, J Derancourt, JP Cano, P Maurel
Drug metabolism and disposition 17 (2), 197-207, 1989
Identification of the cytochrome P-450 induced by macrolide antibiotics in rat liver as the glucocorticoid responsive cytochrome P-450p
SA Wrighton, P Maurel, EG Schuetz, PB Watkins, B Young, PS Guzelian
Biochemistry 24 (9), 2171-2178, 1985
Omeprazole is an aryl hydrocarbon-like inducer of human hepatic cytochrome P450
D Diaz, I Fabrev, M Daujat, B Saint Aubert, P Bories, H Michel, P Maurel
Gastroenterology 99 (3), 737-747, 1990
The human pregnane X receptor: genomic structure and identification and functional characterization of natural allelic variants
J Zhang, P Kuehl, ED Green, JW Touchman, PB Watkins, A Daly, SD Hall, ...
Pharmacogenetics and Genomics 11 (7), 555-572, 2001
Effect of corticosteroids on the expression of cytochromes P450 and on cyclosporin A oxidase activity in primary cultures of human hepatocytes.
L Pichard, I Fabre, M Daujat, J Domergue, H Joyeux, P Maurel
Molecular pharmacology 41 (6), 1047-1055, 1992
The low-density lipoprotein receptor plays a role in the infection of primary human hepatocytes by hepatitis C virus
S Molina, V Castet, C Fournier-Wirth, L Pichard-Garcia, R Avner, D Harats, ...
Journal of hepatology 46 (3), 411-419, 2007
Dual effect of dexamethasone on CYP3A4 gene expression in human hepatocytes: Sequential role of glucocorticoid receptor and pregnane X receptor
JM Pascussi, L Drocourt, S Gerbal‐Chaloin, JM Fabre, P Maurel, ...
European Journal of Biochemistry 268 (24), 6346-6358, 2001
Transcriptional regulation of CYP2C9 gene role of glucocorticoid receptor and constitutive androstane receptor
S Gerbal-Chaloin, M Daujat, JM Pascussi, L Pichard-Garcia, MJ Vilarem, ...
Journal of Biological Chemistry 277 (1), 209-217, 2002
Possible involvement of pregnane X receptor–enhanced CYP24 expression in drug-induced osteomalacia
JM Pascussi, A Robert, M Nguyen, O Walrant-Debray, M Garabedian, ...
The Journal of clinical investigation 115 (1), 177-186, 2005
Effects of imidazole derivatives on cytochromes P450 from human hepatocytes in primary culture.
M Maurice, L Pichard, M Daujat, I Fabre, H Joyeux, J Domergue, P Maurel
The FASEB Journal 6 (2), 752-758, 1992
Dexamethasone enhances constitutive androstane receptor expression in human hepatocytes: consequences on cytochrome P450 gene regulation
JM Pascussi, S Gerbal-Chaloin, JM Fabre, P Maurel, MJ Vilarem
Molecular Pharmacology 58 (6), 1441-1450, 2000
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