Fiona Achcar
Fiona Achcar
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Probing the Metabolic Network in Bloodstream-Form Trypanosoma brucei Using Untargeted Metabolomics with Stable Isotope Labelled Glucose
DJ Creek, M Mazet, F Achcar, J Anderson, DH Kim, R Kamour, P Morand, ...
PLoS pathogens 11 (3), e1004689, 2015
mzMatch–ISO: an R tool for the annotation and relative quantification of isotope-labelled mass spectrometry data
A Chokkathukalam, A Jankevics, DJ Creek, F Achcar, MP Barrett, ...
Bioinformatics 29 (2), 281-283, 2013
Revisiting gametocyte biology in malaria parasites
P Ngotho, AB Soares, F Hentzschel, F Achcar, L Bertuccini, M Marti
FEMS microbiology reviews 43 (4), 401-414, 2019
Handling Uncertainty in Dynamic Models: The Pentose Phosphate Pathway in Trypanosoma brucei
EJ Kerkhoven, F Achcar, VP Alibu, RJ Burchmore, IH Gilbert, M Trybiło, ...
PLoS computational biology 9 (12), e1003371, 2013
AutoClass@ IJM: a powerful tool for Bayesian classification of heterogeneous data in biology
F Achcar, JM Camadro, D Mestivier
Nucleic acids research 37 (suppl_2), W63-W67, 2009
Metabolomic profiling of macrophages determines the discrete metabolomic signature and metabolomic interactome triggered by polarising immune stimuli
KM Rattigan, AW Pountain, C Regnault, F Achcar, IM Vincent, ...
PloS one 13 (3), e0194126, 2018
LC–MS-based absolute metabolite quantification: application to metabolic flux measurement in trypanosomes
DH Kim, F Achcar, R Breitling, KE Burgess, MP Barrett
Metabolomics 11, 1721-1732, 2015
Benzoxaborole treatment perturbs S-adenosyl-L-methionine metabolism in Trypanosoma brucei
PC Steketee, IM Vincent, F Achcar, F Giordani, DH Kim, DJ Creek, ...
PLoS neglected tropical diseases 12 (5), e0006450, 2018
TrypanoCyc: a community-led biochemical pathways database for Trypanosoma brucei
S Shameer, FJ Logan-Klumpler, F Vinson, L Cottret, B Merlet, F Achcar, ...
Nucleic acids research 43 (D1), D637-D644, 2015
Dynamic Modelling under Uncertainty: The Case of Trypanosoma brucei Energy Metabolism
F Achcar, EJ Kerkhoven, SilicoTryp Consortium, BM Bakker, MP Barrett, ...
PLoS computational biology 8 (1), e1002352, 2012
Suramin exposure alters cellular metabolism and mitochondrial energy production in African trypanosomes
M Zoltner, GD Campagnaro, G Taleva, A Burrell, M Cerone, KF Leung, ...
Journal of Biological Chemistry 295 (24), 8331-8347, 2020
Modeling challenges in the synthetic biology of secondary metabolism
R Breitling, F Achcar, E Takano
ACS synthetic biology 2 (7), 373-378, 2013
Deletion of transketolase triggers a stringent metabolic response in promastigotes and loss of virulence in amastigotes of Leishmania mexicana
J Kovářová, AW Pountain, D Wildridge, S Weidt, F Bringaud, ...
PLoS Pathogens 14 (3), e1006953, 2018
Plasmodium falciparum Gametocyte Density and Infectivity in Peripheral Blood and Skin Tissue of Naturally Infected Parasite Carriers in Burkina Faso
E Meibalan, A Barry, MP Gibbins, S Awandu, L Meerstein-Kessel, ...
The Journal of Infectious Diseases 223 (10), 1822-1830, 2021
Trypanosoma brucei: meet the system
F Achcar, EJ Kerkhoven, MP Barrett
Current opinion in microbiology 20, 162-169, 2014
Mapping the metabolism of five amino acids in bloodstream form Trypanosoma brucei using U-13C-labelled substrates and LC–MS
K Johnston, DH Kim, EJ Kerkhoven, R Burchmore, MP Barrett, F Achcar
Bioscience reports 39 (5), BSR20181601, 2019
Explicit consideration of topological and parameter uncertainty gives new insights into a well‐established model of glycolysis
F Achcar, MP Barrett, R Breitling
The FEBS journal 280 (18), 4640-4651, 2013
A Boolean probabilistic model of metabolic adaptation to oxygen in relation to iron homeostasis and oxidative stress
F Achcar, JM Camadro, D Mestivier
BMC systems biology 5, 1-19, 2011
The silicon trypanosome: a test case of iterative model extension in systems biology
F Achcar, A Fadda, JR Haanstra, EJ Kerkhoven, DH Kim, AE Leroux, ...
Advances in microbial physiology 64, 115-143, 2014
Running on empty: a metabolomics approach to investigating changing energy metabolism during fasted exercise and rest
G Blackburn, J Hay, C Skagen, E Paul, F Achcar, J Wilson, C Best, ...
Metabolites 10 (10), 399, 2020
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