Metformin improves healthspan and lifespan in mice A Martin-Montalvo, EM Mercken, SJ Mitchell, HH Palacios, PL Mote, ... Nature communications 4 (1), 1-9, 2013 | 841 | 2013 |
Defective mitophagy in XPA via PARP-1 hyperactivation and NAD+/SIRT1 reduction EF Fang, M Scheibye-Knudsen, LE Brace, H Kassahun, T SenGupta, ... Cell 157 (4), 882-896, 2014 | 362 | 2014 |
SRT1720 improves survival and healthspan of obese mice RK Minor, JA Baur, AP Gomes, TM Ward, A Csiszar, EM Mercken, ... Scientific reports 1 (1), 1-11, 2011 | 249 | 2011 |
A high-fat diet and NAD+ activate Sirt1 to rescue premature aging in cockayne syndrome M Scheibye-Knudsen, SJ Mitchell, EF Fang, T Iyama, T Ward, J Wang, ... Cell metabolism 20 (5), 840-855, 2014 | 212 | 2014 |
NAD+ Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair EF Fang, H Kassahun, DL Croteau, M Scheibye-Knudsen, K Marosi, H Lu, ... Cell metabolism 24 (4), 566-581, 2016 | 203 | 2016 |
Effects of sex, strain, and energy intake on hallmarks of aging in mice SJ Mitchell, J Madrigal-Matute, M Scheibye-Knudsen, E Fang, M Aon, ... Cell metabolism 23 (6), 1093-1112, 2016 | 203 | 2016 |
Nuclear DNA damage signalling to mitochondria in ageing EF Fang, M Scheibye-Knudsen, KF Chua, MP Mattson, DL Croteau, ... Nature reviews Molecular cell biology 17 (5), 308-321, 2016 | 196 | 2016 |
Protecting the mitochondrial powerhouse M Scheibye-Knudsen, EF Fang, DL Croteau, DM Wilson III, VA Bohr Trends in cell biology 25 (3), 158-170, 2015 | 195 | 2015 |
Cockayne syndrome group B protein prevents the accumulation of damaged mitochondria by promoting mitochondrial autophagy M Scheibye-Knudsen, M Ramamoorthy, P Sykora, S Maynard, PC Lin, ... Journal of Experimental Medicine 209 (4), 855-869, 2012 | 166 | 2012 |
SRT 2104 extends survival of male mice on a standard diet and preserves bone and muscle mass EM Mercken, SJ Mitchell, A Martin‐Montalvo, RK Minor, M Almeida, ... Aging cell 13 (5), 787-796, 2014 | 161 | 2014 |
DNA damage, DNA repair, aging, and neurodegeneration S Maynard, EF Fang, M Scheibye-Knudsen, DL Croteau, VA Bohr Cold Spring Harbor perspectives in medicine 5 (10), a025130, 2015 | 156 | 2015 |
A research agenda for aging in China in the 21st century EF Fang, M Scheibye-Knudsen, HJ Jahn, J Li, L Ling, H Guo, X Zhu, ... Ageing research reviews 24, 197-205, 2015 | 146 | 2015 |
Mitophagy in neurodegeneration and aging EM Fivenson, S Lautrup, N Sun, M Scheibye-Knudsen, T Stevnsner, ... Neurochemistry international 109, 202-209, 2017 | 143 | 2017 |
Animal models of aging research: implications for human aging and age-related diseases SJ Mitchell, M Scheibye-Knudsen, DL Longo, R de Cabo Annu. Rev. Anim. Biosci. 3 (1), 283-303, 2015 | 133 | 2015 |
Cockayne syndrome: clinical features, model systems and pathways AC Karikkineth, M Scheibye-Knudsen, E Fivenson, DL Croteau, VA Bohr Ageing research reviews 33, 3-17, 2017 | 128 | 2017 |
Cockayne syndrome group B protein promotes mitochondrial DNA stability by supporting the DNA repair association with the mitochondrial membrane MD Aamann, MM Sorensen, C Hvitby, BR Berquist, M Muftuoglu, J Tian, ... The FASEB Journal 24 (7), 2334-2346, 2010 | 127 | 2010 |
Negative regulation of STAT3 protein-mediated cellular respiration by SIRT1 protein M Bernier, RK Paul, A Martin-Montalvo, M Scheibye-Knudsen, S Song, ... Journal of Biological Chemistry 286 (22), 19270-19279, 2011 | 114 | 2011 |
3‐Hydroxybutyrate regulates energy metabolism and induces BDNF expression in cerebral cortical neurons K Marosi, SW Kim, K Moehl, M Scheibye‐Knudsen, A Cheng, R Cutler, ... Journal of neurochemistry 139 (5), 769-781, 2016 | 102 | 2016 |
Population specific biomarkers of human aging: a big data study using South Korean, Canadian, and Eastern European patient populations P Mamoshina, K Kochetov, E Putin, F Cortese, A Aliper, WS Lee, SM Ahn, ... The Journals of Gerontology: Series A 73 (11), 1482-1490, 2018 | 64 | 2018 |
Tomatidine enhances lifespan and healthspan in C. elegans through mitophagy induction via the SKN-1/Nrf2 pathway EF Fang, TB Waltz, H Kassahun, Q Lu, JS Kerr, M Morevati, EM Fivenson, ... Scientific reports 7 (1), 1-13, 2017 | 63 | 2017 |