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Hannah C. Safford
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Massively parallel pooled screening reveals genomic determinants of nanoparticle delivery
N Boehnke, JP Straehla, HC Safford, M Kocak, MG Rees, M Ronan, ...
Science 377 (6604), eabm5551, 2022
902022
A predictive microfluidic model of human glioblastoma to assess trafficking of blood–brain barrier-penetrant nanoparticles
JP Straehla, C Hajal, HC Safford, GS Offeddu, N Boehnke, TG Dacoba, ...
Proceedings of the National Academy of Sciences 119 (23), e2118697119, 2022
502022
Ionizable Lipid Nanoparticles for In Vivo mRNA Delivery to the Placenta during Pregnancy
KL Swingle, HC Safford, HC Geisler, AG Hamilton, AS Thatte, ...
Journal of the American Chemical Society 145 (8), 4691-4706, 2023
432023
β-Lactamase triggered visual detection of bacteria using cephalosporin functionalized biomaterials
D Alkekhia, H Safford, S Shukla, R Hopson, A Shukla
Chemical Communications 56 (75), 11098-11101, 2020
92020
Orthogonal Design of Experiments for Engineering of Lipid Nanoparticles for mRNA Delivery to the Placenta
HC Safford, KL Swingle, HC Geisler, AG Hamilton, AS Thatte, ...
Small, 2303568, 2023
72023
In vivo mRNA CAR T cell engineering via targeted ionizable lipid nanoparticles with extrahepatic tropism
MM Billingsley, N Gong, AJ Mukalel, AS Thatte, R El‐Mayta, SK Patel, ...
Small 20 (11), 2304378, 2024
62024
Rational design of nanomedicine for placental disorders: birthing a new era in women's reproductive health
HC Geisler, HC Safford, MJ Mitchell
Small, 2300852, 2023
42023
Bile acid-containing lipid nanoparticles enhance extrahepatic mRNA delivery
SK Patel, MM Billingsley, AJ Mukalel, AS Thatte, AG Hamilton, N Gong, ...
Theranostics 14 (1), 1, 2024
32024
Oxidized mRNA Lipid Nanoparticles for In Situ Chimeric Antigen Receptor Monocyte Engineering
AJ Mukalel, AG Hamilton, MM Billingsley, J Li, AS Thatte, X Han, ...
Advanced Functional Materials, 2312038, 2024
12024
DDEL-04. ENGINEERED NANOCARRIERS TO ENHANCE DRUG DELIVERY ACROSS THE BLOOD-BRAIN BARRIER
JP Straehla, C Hajal, H Safford, G Offeddu, J Wyckoff, RD Kamm, ...
Neuro-Oncology 22 (Suppl 3), iii284, 2020
12020
Chromogenic beta-lactamase substrate
A Shukla, D Alkekhia, S Shukla, H Safford
US Patent 11,957,690, 2024
2024
DDEL-17. POOLED CANCER CELL SCREENING IDENTIFIES GENOMIC DETERMINANTS OF NANOPARTICLE DELIVERY TO CANCER CELLS: SUB ANALYSIS OF CENTRAL NERVOUS SYSTEM TUMOR CELL LINES
J Straehla, N Boehnke, H Safford, M Kocak, M Rees, M Ronan, ...
Neuro-Oncology 24 (Supplement_7), vii97-vii97, 2022
2022
Identification of a predictive biomarker for liposomal nanoparticle delivery through pan-cancer pooled screening
JP Straehla, N Boehnke, H Safford, M Kocak, MG Rees, M Ronan, ...
Cancer Research 82 (12_Supplement), 293-293, 2022
2022
A PREDICTIVE MICROFLUIDIC MODEL OF VASCULARIZED GLIOMA TUMORS TO ASSESS TRAFFICKING OF THERAPEUTICS ACROSS THE BLOOD-BRAIN BARRIER
C Hajal, J Straehla, G Offeddu, H Safford, P Hammond, R Kamm
NEURO-ONCOLOGY 23, 217-218, 2021
2021
LAYER-BY-LAYER NANOPARTICLES DESIGNED FOR DUAL BLOOD-BRAIN BARRIER AND GLIOMA TARGETING
J Straehla, C Hajal, H Safford, G Offeddu, J Wyckoff, R Kamm, ...
NEURO-ONCOLOGY 23, 168-169, 2021
2021
Development of a multi-omic, pooled cancer cell screen for nanoparticle delivery
JP Straehla, N Boehnke, M Kocak, M Ronan, H Safford, MG Rees, ...
Cancer Research 81 (13_Supplement), 309-309, 2021
2021
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