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Jennifer A Miles
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Selective and potent proteomimetic inhibitors of intracellular protein–protein interactions
A Barnard, K Long, HL Martin, JA Miles, TA Edwards, DC Tomlinson, ...
Angewandte Chemie 127 (10), 3003-3008, 2015
1112015
Double quick, double click reversible peptide “stapling”
CM Grison, GM Burslem, JA Miles, LKA Pilsl, DJ Yeo, Z Imani, ...
Chemical Science 8 (7), 5166-5171, 2017
892017
Structure of the human FANCL RING-Ube2T complex reveals determinants of cognate E3-E2 selection
C Hodson, A Purkiss, JA Miles, H Walden
Structure 22 (2), 337-344, 2014
872014
Hydrocarbon constrained peptides–understanding preorganisation and binding affinity
JA Miles, DJ Yeo, P Rowell, S Rodriguez-Marin, CM Pask, SL Warriner, ...
Chemical science 7 (6), 3694-3702, 2016
842016
An α‐Helix‐Mimicking 12, 13‐Helix: Designed α/β/γ‐Foldamers as Selective Inhibitors of Protein–Protein Interactions
CM Grison, JA Miles, S Robin, AJ Wilson, DJ Aitken
Angewandte Chemie International Edition 55 (37), 11096-11100, 2016
652016
Stereocontrolled protein surface recognition using chiral oligoamide proteomimetic foldamers
V Azzarito, JA Miles, J Fisher, TA Edwards, SL Warriner, AJ Wilson
Chemical Science 6 (4), 2434-2443, 2015
652015
Structural analysis of human FANCL, the E3 ligase in the Fanconi anemia pathway
C Hodson, AR Cole, LPC Lewis, JA Miles, A Purkiss, H Walden
Journal of Biological Chemistry 286 (37), 32628-32637, 2011
632011
Orthogonal functionalisation of α-helix mimetics
A Barnard, K Long, DJ Yeo, JA Miles, V Azzarito, GM Burslem, ...
Organic & Biomolecular Chemistry 12 (35), 6794-6799, 2014
312014
Inhibition of the p53/hDM2 protein-protein interaction by cyclometallated iridium (III) compounds
LJ Liu, B He, JA Miles, W Wang, Z Mao, WI Che, JJ Lu, XP Chen, ...
Oncotarget 7 (12), 13965, 2016
282016
The Fanconi anemia DNA repair pathway is regulated by an interaction between ubiquitin and the E2-like fold domain of FANCL
JA Miles, MG Frost, E Carroll, ML Rowe, MJ Howard, A Sidhu, ...
Journal of Biological Chemistry 290 (34), 20995-21006, 2015
272015
Multivalent helix mimetics for PPI-inhibition
A Barnard, JA Miles, GM Burslem, AM Barker, AJ Wilson
Organic & Biomolecular Chemistry 13 (1), 258-264, 2015
252015
A catalytic protein–proteomimetic complex: using aromatic oligoamide foldamers as activators of RNase S
Z Hegedus, CM Grison, JA Miles, S Rodriguez-Marin, SL Warriner, ...
Chemical Science 10 (14), 3956-3962, 2019
202019
Evaluating the conformation of recombinant domain I of β2-glycoprotein I and its interaction with human monoclonal antibodies
C Pericleous, J Miles, D Esposito, A Garza-Garcia, PC Driscoll, ...
Molecular Immunology 49 (1-2), 56-63, 2011
172011
Identification of a cyanobacterial aldehyde dehydrogenase that produces retinoic acid in vitro
JA Miles, P Machattou, D Nevin-Jones, ME Webb, A Millard, DJ Scanlan, ...
Biochemical and biophysical research communications 510 (1), 27-34, 2019
122019
Selective Affimers Recognise the BCL‐2 Family Proteins BCL‐xL and MCL‐1 through Noncanonical Structural Motifs**
JA Miles, F Hobor, CH Trinh, J Taylor, C Tiede, PR Rowell, BR Jackson, ...
ChemBioChem 22 (1), 232-240, 2021
112021
A case study of eukaryogenesis: the evolution of photoreception by photolyase/cryptochrome proteins
JA Miles, TA Davies, RD Hayman, G Lorenzen, J Taylor, M Anjarwalla, ...
Journal of molecular evolution 88, 662-673, 2020
62020
The evolutionary origins of peroxynitrite signalling
JA Miles, JL Egan, JA Fowler, P Machattou, AD Millard, CJ Perry, ...
Biochemical and Biophysical Research Communications 580, 107-112, 2021
52021
Peptide & NMR spectroscopy studies of recombinant Domain I confirm conformationally correct Domain I and non-linear epitope binding to anti-Domain I antiphospholipid antibodies
C Pericleous, T Disu, J Miles, D Esposito, A Garza-Garcia, P Driscoll, ...
22010
Inhibition of Aurora‐A/N‐Myc Protein–Protein Interaction Using Peptidomimetics: Understanding the Role of Peptide Cyclization
RS Dawber, D Gimenez, M Batchelor, JA Miles, MH Wright, R Bayliss, ...
ChemBioChem 25 (2), e202300649, 2024
2024
Mechanisms of monoubiquitination in the Fanconi anemia pathway
JA Miles
UCL (University College London), 2014
2014
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Articles 1–20