Prolonged Mek1/2 suppression impairs the developmental potential of embryonic stem cells J Choi, AJ Huebner, K Clement, RM Walsh, A Savol, K Lin, H Gu, ... Nature 548 (7666), 219-223, 2017 | 250 | 2017 |
Nrf2 links epidermal barrier function with antioxidant defense M Schäfer, H Farwanah, AH Willrodt, AJ Huebner, K Sandhoff, D Roop, ... EMBO molecular medicine 4 (5), 364-379, 2012 | 193 | 2012 |
Lineage conversion induced by pluripotency factors involves transient passage through an iPSC stage O Bar-Nur, C Verheul, AG Sommer, J Brumbaugh, BA Schwarz, I Lipchina, ... Nature biotechnology 33 (7), 761-768, 2015 | 121 | 2015 |
Activation of Nrf2 in keratinocytes causes chloracne (MADISH)‐like skin disease in mice M Schäfer, AH Willrodt, S Kurinna, AS Link, H Farwanah, A Geusau, ... EMBO molecular medicine 6 (4), 442-457, 2014 | 98 | 2014 |
The RNA helicase DDX6 controls cellular plasticity by modulating P-body homeostasis B Di Stefano, EC Luo, C Haggerty, S Aigner, J Charlton, J Brumbaugh, ... Cell stem cell 25 (5), 622-638. e13, 2019 | 91 | 2019 |
Direct reprogramming of mouse fibroblasts into functional skeletal muscle progenitors O Bar-Nur, MFM Gerli, B Di Stefano, AE Almada, A Galvin, A Coffey, ... Stem Cell Reports 10 (5), 1505-1521, 2018 | 86 | 2018 |
Reduced MEK inhibition preserves genomic stability in naive human embryonic stem cells B Di Stefano, M Ueda, S Sabri, J Brumbaugh, AJ Huebner, A Sahakyan, ... Nature methods 15 (9), 732-740, 2018 | 82 | 2018 |
Sox2 suppresses gastric tumorigenesis in mice A Sarkar, AJ Huebner, R Sulahian, A Anselmo, X Xu, K Flattery, N Desai, ... Cell reports 16 (7), 1929-1941, 2016 | 78 | 2016 |
DUSP9 modulates DNA hypomethylation in female mouse pluripotent stem cells J Choi, K Clement, AJ Huebner, J Webster, CM Rose, J Brumbaugh, ... Cell stem cell 20 (5), 706-719. e7, 2017 | 75 | 2017 |
An intermediate pluripotent state controlled by microRNAs is required for the naive-to-primed stem cell transition P Du, M Pirouz, J Choi, AJ Huebner, K Clement, A Meissner, ... Cell stem cell 22 (6), 851-864. e5, 2018 | 61 | 2018 |
Amniotic fluid activates the nrf2/keap1 pathway to repair an epidermal barrier defect in utero AJ Huebner, D Dai, M Morasso, EE Schmidt, M Schäfer, S Werner, ... Developmental cell 23 (6), 1238-1246, 2012 | 57 | 2012 |
Inducible histone K-to-M mutations are dynamic tools to probe the physiological role of site-specific histone methylation in vitro and in vivo J Brumbaugh, IS Kim, F Ji, AJ Huebner, B Di Stefano, BA Schwarz, ... Nature cell biology 21 (11), 1449-1461, 2019 | 50 | 2019 |
Lce1 family members are Nrf2-target genes that are induced to compensate for the loss of loricrin Y Ishitsuka, AJ Huebner, RH Rice, PJ Koch, VV Speransky, AC Steven, ... Journal of Investigative Dermatology 136 (8), 1656-1663, 2016 | 39 | 2016 |
Aurora kinase-A deficiency during skin development impairs cell division and stratification EC Torchia, L Zhang, AJ Huebner, S Sen, DR Roop Journal of Investigative Dermatology 133 (1), 78-86, 2013 | 22 | 2013 |
Planar cell polarity effector gene Intu regulates cell fate-specific differentiation of keratinocytes through the primary cilia D Dai, L Li, A Huebner, H Zeng, E Guevara, DJ Claypool, A Liu, J Chen Cell Death & Differentiation 20 (1), 130-138, 2013 | 22 | 2013 |
Dissecting dual roles of MyoD during lineage conversion to mature myocytes and myogenic stem cells M Yagi, F Ji, J Charlton, S Cristea, K Messemer, N Horwitz, B Di Stefano, ... Genes & Development 35 (17-18), 1209-1228, 2021 | 19 | 2021 |
Transcription factor-mediated intestinal metaplasia and the role of a shadow enhancer H Singh, D Seruggia, S Madha, M Saxena, AK Nagaraja, Z Wu, J Zhou, ... Genes & Development 36 (1-2), 38-52, 2022 | 12 | 2022 |
H3K36 methylation maintains cell identity by regulating opposing lineage programmes MS Hoetker, M Yagi, B Di Stefano, J Langerman, S Cristea, LP Wong, ... Nature cell biology 25 (8), 1121-1134, 2023 | 7 | 2023 |
Dissection of gastric homeostasis in vivo facilitates permanent capture of isthmus-like stem cells in vitro AJ Huebner, RA Gorelov, R Deviatiiarov, S Demharter, T Kull, RM Walsh, ... Nature Cell Biology 25 (3), 390-403, 2023 | 6 | 2023 |
Derivation and long-term propagation of mouse embryonic stem cells J Choi, K Hochedlinger, A Huebner | 1 | 2017 |