Tjaart de Beer
Tjaart de Beer
F. Hoffman-La Roche Ltd
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Cited by
Cited by
SWISS-MODEL: homology modelling of protein structures and complexes
A Waterhouse, M Bertoni, S Bienert, G Studer, G Tauriello, R Gumienny, ...
Nucleic acids research 46 (W1), W296-W303, 2018
The SWISS-MODEL Repository—new features and functionality
S Bienert, A Waterhouse, TAP de Beer, G Tauriello, G Studer, L Bordoli, ...
Nucleic acids research 45 (D1), D313-D319, 2017
PDBsum additions
TAP De Beer, K Berka, JM Thornton, RA Laskowski
Nucleic acids research 42 (D1), D292-D296, 2014
The Catalytic Site Atlas 2.0: cataloging catalytic sites and residues identified in enzymes
N Furnham, GL Holliday, TAP de Beer, JOB Jacobsen, WR Pearson, ...
Nucleic acids research 42 (D1), D485-D489, 2014
Sequence-based prediction for vaccine strain selection and identification of antigenic variability in foot-and-mouth disease virus
R Reeve, B Blignaut, JJ Esterhuysen, P Opperman, L Matthews, EE Fry, ...
PLoS computational biology 6 (12), e1001027, 2010
Amino acid changes in disease-associated variants differ radically from variants observed in the 1000 genomes project dataset
TAP de Beer, RA Laskowski, SL Parks, B Sipos, N Goldman, JM Thornton
PLoS computational biology 9 (12), e1003382, 2013
Structure-function study of a Plasmodium falciparum Hsp70 using three dimensional modelling and in vitro analyses
A Shonhai, M Botha, TAP de Beer, A Boshoff, GL Blatch
Protein and peptide letters 15 (10), 1117-1125, 2008
Mapping of amino acid residues responsible for adhesion of cell culture-adapted foot-and-mouth disease SAT type viruses
FF Maree, B Blignaut, TAP De Beer, N Visser, EA Rieder
Virus research 153 (1), 82-91, 2010
Predicting antigenic sites on the foot-and-mouth disease virus capsid of the South African Territories types using virus neutralization data
FF Maree, B Blignaut, JJ Esterhuysen, TAP De Beer, J Theron, HG O’Neill, ...
Journal of General Virology 92 (10), 2297-2309, 2011
Antimalarial drug discovery: in silico structural biology and rational drug design
TAP De Beer, GA Wells, PB Burger, F Joubert, E Marechal, L Birkholtz, ...
Infectious Disorders-Drug Targets (Formerly Current Drug Targets-Infectious …, 2009
Strømme Syndrome Is a Ciliary Disorder Caused by Mutations in CENPF
I Filges, E Bruder, K Brandal, S Meier, DE Undlien, TR Waage, I Hoesli, ...
Human mutation 37 (4), 359-363, 2016
Protein homology modelling and its use in South Africa: research in action
AO Tastan Bishop, TAP De Beer, F Joubert
South African Journal of Science 104 (1), 2-6, 2008
Elucidation of sulfadoxine resistance with structural models of the bifunctional Plasmodium falciparum dihydropterin pyrophosphokinase–dihydropteroate synthase
TAP de Beer, AI Louw, F Joubert
Bioorganic & medicinal chemistry 14 (13), 4433-4443, 2006
Analysis of SAT type foot-and-mouth disease virus capsid proteins and the identification of putative amino acid residues affecting virus stability
FF Maree, B Blignaut, TAP de Beer, E Rieder
PLoS One 8 (5), e61612, 2013
The SIB Swiss Institute of Bioinformatics’ resources: focus on curated databases
SIB Swiss Institute of Bioinformatics Members
Nucleic acids research 44 (D1), D27-D37, 2016
1,000 structures and more from the MCSG
D Lee, TAP de Beer, RA Laskowski, JM Thornton, CA Orengo
BMC structural biology 11 (1), 1, 2011
The malarial drug target Plasmodium falciparum 1-deoxy-d-xylulose-5-phosphate reductoisomerase (PfDXR): development of a 3-D model for identification of novel, structural and …
JL Goble, MR Adendorff, TAP de Beer, LL Stephens, GL Blatch
Protein and peptide letters 17 (1), 109-120, 2010
Discovery: an interactive resource for the rational selection and comparison of putative drug target proteins in malaria
F Joubert, CM Harrison, RJ Koegelenberg, CJ Odendaal, TAP de Beer
Malaria Journal 8 (1), 1-8, 2009
Common sequence variants affect molecular function more than rare variants?
Y Mahlich, J Reeb, M Hecht, M Schelling, TAP De Beer, Y Bromberg, ...
Scientific reports 7 (1), 1-13, 2017
Current challenges in genome annotation through structural biology and bioinformatics
N Furnham, TAP de Beer, JM Thornton
Current opinion in structural biology 22 (5), 594-601, 2012
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