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Dhanasekaran Shanmugam
Dhanasekaran Shanmugam
Senior Principal Scientist, CSIR-National Chemical Laboratory, Pune, India.
Verified email at ncl.res.in
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Year
Using OrthoMCL to assign proteins to OrthoMCL‐DB groups or to cluster proteomes into new ortholog groups
S Fischer, BP Brunk, F Chen, X Gao, OS Harb, JB Iodice, D Shanmugam, ...
Current protocols in bioinformatics 35 (1), 6.12. 1-6.12. 19, 2011
4792011
Genomic-scale prioritization of drug targets: the TDR Targets database
F Agüero, B Al-Lazikani, M Aslett, M Berriman, FS Buckner, RK Campbell, ...
Nature reviews Drug discovery 7 (11), 900-907, 2008
3552008
Comparative Genomics of the Apicomplexan Parasites Toxoplasma gondii and Neospora caninum: Coccidia Differing in Host Range and Transmission Strategy
AJ Reid, SJ Vermont, JA Cotton, D Harris, GA Hill-Cawthorne, ...
PLoS pathogens 8 (3), e1002567, 2012
2632012
Chromerid genomes reveal the evolutionary path from photosynthetic algae to obligate intracellular parasites
YH Woo, H Ansari, TD Otto, CM Klinger, M Kolisko, J Michálek, A Saxena, ...
elife 4, e06974, 2015
2182015
Identification of Attractive Drug Targets in Neglected-Disease Pathogens Using an In Silico Approach
GJ Crowther, D Shanmugam, SJ Carmona, MA Doyle, C Hertz-Fowler, ...
PLoS neglected tropical diseases 4 (8), e804, 2010
1922010
TDR Targets: a chemogenomics resource for neglected diseases
MP Magariños, SJ Carmona, GJ Crowther, SA Ralph, DS Roos, ...
Nucleic acids research 40 (D1), D1118-D1127, 2012
1532012
Comparative genomics of the pathogenic ciliate Ichthyophthirius multifiliis, its free-living relatives and a host species provide insights into adoption of a parasitic …
RS Coyne, L Hannick, D Shanmugam, JB Hostetler, D Brami, VS Joardar, ...
Genome Biology 12, 1-26, 2011
1382011
Widespread occurrence of the Plasmodium falciparum chloroquine resistance transporter (Pfcrt) gene haplotype SVMNT in P. falciparum malaria in India
PG Vathsala, A Pramanik, S Dhanasekaran, CU Devi, CR Pillai, ...
American Journal of Tropical Medicine and Hygiene 70 (3), 256-259, 2004
1092004
Import of host δ-aminolevulinate dehydratase into the malarial parasite: identification of a new drug target
ZQ Bonday, S Dhanasekaran, PN Rangarajan, G Padmanaban
Nature medicine 6 (8), 898-903, 2000
1072000
δ-Aminolevulinic acid dehydratase from Plasmodium falciparum: indigenous versus imported
S Dhanasekaran, NR Chandra, BKC Sagar, PN Rangarajan, ...
Journal of Biological Chemistry 279 (8), 6934-6942, 2004
912004
Involvement of δ-aminolaevulinate synthase encoded by the parasite gene in de novo haem synthesis by Plasmodium falciparum
S Varadharajan, S Dhanasekaran, ZQ Bonday, PN Rangarajan, ...
Biochemical Journal 367 (2), 321-327, 2002
872002
A novel multifunctional oligonucleotide microarray for Toxoplasma gondii
A Bahl, PH Davis, M Behnke, F Dzierszinski, M Jagalur, F Chen, ...
BMC genomics 11, 1-18, 2010
742010
The search for the missing link: a relic plastid in Perkinsus?
JAF Robledo, E Caler, M Matsuzaki, PJ Keeling, D Shanmugam, DS Roos, ...
International journal for parasitology 41 (12), 1217-1229, 2011
712011
Glycolysis is important for optimal asexual growth and formation of mature tissue cysts by Toxoplasma gondii
A Shukla, KL Olszewski, M Llinás, LM Rommereim, BA Fox, DJ Bzik, ...
International journal for parasitology 48 (12), 955-968, 2018
512018
TDR Targets 6: driving drug discovery for human pathogens through intensive chemogenomic data integration
L Urán Landaburu, AJ Berenstein, S Videla, P Maru, D Shanmugam, ...
Nucleic acids research 48 (D1), D992-D1005, 2020
462020
Specific stereoisomeric conformations determine the drug potency of cladosporin scaffold against malarial parasite
P Das, P Babbar, N Malhotra, M Sharma, GR Jachak, RG Gonnade, ...
Journal of Medicinal Chemistry 61 (13), 5664-5678, 2018
452018
Highly diverged novel subunit composition of apicomplexan F-type ATP synthase identified from Toxoplasma gondii
R Salunke, T Mourier, M Banerjee, A Pain, D Shanmugam
PLoS Biology 16 (7), e2006128, 2018
392018
Targeted Phenotypic Screening in Plasmodium falciparum and Toxoplasma gondii Reveals Novel Modes of Action of Medicines for Malaria Venture Malaria Box Molecules
CR Subramanian G, Belekar MA, Shukla A, Tong JX, Sinha A, Chu TTT, Kulkarni ...
mSphere 3 (1), pii: e00534-17, 2018
31*2018
Plastid-associated porphobilinogen synthase from Toxoplasma gondii: kinetic and structural properties validate therapeutic potential
D Shanmugam, B Wu, U Ramirez, EK Jaffe, DS Roos
Journal of Biological Chemistry 285 (29), 22122-22131, 2010
312010
Insights from a Pan India sero-epidemiological survey (phenome-India cohort) for SARS-CoV2
S Naushin, V Sardana, R Ujjainiya, N Bhatheja, R Kutum, AK Bhaskar, ...
Elife 10, e66537, 2021
282021
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