Amy. E.M. Beedle
Amy. E.M. Beedle
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Cited by
Force triggers YAP nuclear entry by regulating transport across nuclear pores
A Elosegui-Artola, I Andreu, AEM Beedle, A Lezamiz, M Uroz, ...
Cell 171 (6), 1397-1410. e14, 2017
Steering chemical reactions with force
S Garcia-Manes, AEMI Beedle
Nature Chemistry 1 (11), 0083, 2017
Protein S-sulfenylation is a fleeting molecular switch that regulates non-enzymatic oxidative folding
AEM Beedle, S Lynham, S Garcia-Manyes
Nature communications 7 (1), 1-10, 2016
The mechanochemistry of copper reports on the directionality of unfolding in model cupredoxin proteins
AEM Beedle, A Lezamiz, G Stirnemann, S Garcia-Manyes
Nature communications 6 (1), 1-9, 2015
Single-molecule force spectroscopy predicts a misfolded, domain-swapped conformation in human γD-crystallin protein
S Garcia-Manyes, D Giganti, CL Badilla, A Lezamiz, J Perales-Calvo, ...
Journal of Biological Chemistry 291 (8), 4226-4235, 2016
Forcing the reversibility of a mechanochemical reaction
AEM Beedle, M Mora, CT Davis, AP Snijders, G Stirnemann, ...
Nature communications 9 (1), 1-9, 2018
Binding of myomesin to obscurin-like-1 at the muscle M-band provides a strategy for isoform-specific mechanical protection
S Pernigo, A Fukuzawa, AEM Beedle, M Holt, A Round, A Pandini, ...
Structure 25 (1), 107-120, 2017
Tailoring protein nanomechanics with chemical reactivity
AEM Beedle, M Mora, S Lynham, G Stirnemann, S Garcia-Manyes
Nature communications 8 (1), 1-11, 2017
The mechanical stability of proteins regulates their translocation rate into the cell nucleus
E Infante, A Stannard, SJ Board, P Rico-Lastres, E Rostkova, AEM Beedle, ...
Nature Physics 15 (9), 973-981, 2019
Steering chemical reactions with force
S Garcia-Manyes, AEM Beedle
Nature Reviews Chemistry 1 (11), 1-16, 2017
Mechanobiology—chemical origin of membrane mechanical resistance and force-dependent signaling
AEM Beedle, A Williams, J Relat-Goberna, S Garcia-Manyes
Current opinion in chemical biology 29, 87-93, 2015
The nanomechanics of lipid multibilayer stacks exhibits complex dynamics
J Relat‐Goberna, AEM Beedle, S Garcia‐Manyes
small 13 (24), 1700147, 2017
Molecular fluctuations as a ruler of force-induced protein conformations
A Stannard, M Mora, AEM Beedle, M Castro-López, S Board, ...
Nano letters 21 (7), 2953-2961, 2021
Mechanosensitivity of nucleocytoplasmic transport
I Andreu, I Granero-Moya, NR Chahare, K Clein, MM Jordŕn, AEM Beedle, ...
bioRxiv, 2021
The force loading rate drives cell mechanosensing through both reinforcement and fluidization
I Andreu, B Falcones, S Hurst, N Chahare, X Quiroga, AL Le Roux, ...
bioRxiv, 2021
Tailoring protein nanomechanics through chemical reactivity with single bond resolution
AEMI Beedle
King's College London, 2018
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