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Amy. E.M. Beedle
Amy. E.M. Beedle
Verified email at kcl.ac.uk
Title
Cited by
Cited by
Year
Force triggers YAP nuclear entry by regulating transport across nuclear pores
A Elosegui-Artola, I Andreu, AEM Beedle, A Lezamiz, M Uroz, ...
Cell 171 (6), 1397-1410. e14, 2017
11242017
Steering chemical reactions with force
S Garcia-Manyes, AEM Beedle
Nature Reviews Chemistry 1 (11), 0083, 2017
1152017
Mechanical force application to the nucleus regulates nucleocytoplasmic transport
I Andreu, I Granero-Moya, NR Chahare, K Clein, M Molina-Jordán, ...
Nature cell biology 24 (6), 896-905, 2022
722022
Protein S-sulfenylation is a fleeting molecular switch that regulates non-enzymatic oxidative folding
AEM Beedle, S Lynham, S Garcia-Manyes
Nature communications 7 (1), 12490, 2016
692016
The mechanochemistry of copper reports on the directionality of unfolding in model cupredoxin proteins
AEM Beedle, A Lezamiz, G Stirnemann, S Garcia-Manyes
Nature communications 6 (1), 7894, 2015
672015
The force loading rate drives cell mechanosensing through both reinforcement and cytoskeletal softening
I Andreu, B Falcones, S Hurst, N Chahare, X Quiroga, AL Le Roux, ...
Nature communications 12 (1), 4229, 2021
632021
Forcing the reversibility of a mechanochemical reaction
AEM Beedle, M Mora, CT Davis, AP Snijders, G Stirnemann, ...
Nature Communications 9 (1), 3155, 2018
612018
Single-molecule force spectroscopy predicts a misfolded, domain-swapped conformation in human γD-crystallin protein
S Garcia-Manyes, D Giganti, CL Badilla, A Lezamiz, J Perales-Calvo, ...
Journal of Biological Chemistry 291 (8), 4226-4235, 2016
442016
The mechanical stability of proteins regulates their translocation rate into the cell nucleus
E Infante, A Stannard, SJ Board, P Rico-Lastres, E Rostkova, AEM Beedle, ...
Nature physics 15 (9), 973-981, 2019
402019
Binding of myomesin to obscurin-like-1 at the muscle M-band provides a strategy for isoform-specific mechanical protection
S Pernigo, A Fukuzawa, AEM Beedle, M Holt, A Round, A Pandini, ...
Structure 25 (1), 107-120, 2017
362017
Tailoring protein nanomechanics with chemical reactivity
AEM Beedle, M Mora, S Lynham, G Stirnemann, S Garcia-Manyes
Nature Communications 8 (1), 15658, 2017
342017
The laminin–keratin link shields the nucleus from mechanical deformation and signalling
Z Kechagia, P Sáez, M Gómez-González, B Canales, S Viswanadha, ...
Nature Materials 22 (11), 1409-1420, 2023
202023
Mechanobiology—chemical origin of membrane mechanical resistance and force-dependent signaling
AEM Beedle, A Williams, J Relat-Goberna, S Garcia-Manyes
Current opinion in chemical biology 29, 87-93, 2015
202015
The nanomechanics of lipid multibilayer stacks exhibits complex dynamics
J Relat‐Goberna, AEM Beedle, S Garcia‐Manyes
small 13 (24), 1700147, 2017
172017
Molecular fluctuations as a ruler of force-induced protein conformations
A Stannard, M Mora, AEM Beedle, M Castro-López, S Board, ...
Nano letters 21 (7), 2953-2961, 2021
162021
The role of single-protein elasticity in mechanobiology
AEM Beedle, S Garcia-Manyes
Nature Reviews Materials 8 (1), 10-24, 2023
132023
The reversibility of cellular mechano-activation
AEM Beedle, P Roca-Cusachs
Current Opinion in Cell Biology 84, 102229, 2023
52023
Mechanosensitivity of nucleocytoplasmic transport
I Andreu, I Granero-Moya, NR Chahare, K Clein, MM Jordŕn, AEM Beedle, ...
bioRxiv, 2021.07. 23.453478, 2021
52021
In search of a softer environment
AEM Beedle, P Roca-Cusachs
Nature Materials 21 (9), 995-996, 2022
32022
Fibrillar adhesion dynamics govern the timescales of nuclear mechano-response via the vimentin cytoskeleton
AEM Beedle, A Jaganathan, A Albajar-Sigales, FM Yavitt, K Bera, ...
bioRxiv, 2023
2023
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Articles 1–20