| Targeting Mnks for cancer therapy J Hou, F Lam, C Proud, S Wang Oncotarget 3 (2), 118, 2012 | 179 | 2012 |
| 5-N-Methylated Quindoline Derivatives as Telomeric G-Quadruplex Stabilizing Ligands: Effects of 5-N Positive Charge on Quadruplex Binding Affinity and Cell … YJ Lu, TM Ou, JH Tan, JQ Hou, WY Shao, D Peng, N Sun, XD Wang, ... Journal of medicinal chemistry 51 (20), 6381-6392, 2008 | 152 | 2008 |
| 9-N-Substituted berberine derivatives: stabilization of G-quadruplex DNA and down-regulation of oncogene c-myc Y Ma, TM Ou, JQ Hou, YJ Lu, JH Tan, LQ Gu, ZS Huang Bioorganic & medicinal chemistry 16 (16), 7582-7591, 2008 | 150 | 2008 |
| Inhibition of Cell Proliferation by Quindoline Derivative (SYUIQ-05) through its Preferential Interaction with c-myc Promoter G-Quadruplex TM Ou, J Lin, YJ Lu, JQ Hou, JH Tan, SH Chen, Z Li, YP Li, D Li, LQ Gu, ... Journal of medicinal chemistry 54 (16), 5671-5679, 2011 | 127 | 2011 |
| Isaindigotone derivatives: a new class of highly selective ligands for telomeric G-quadruplex DNA JH Tan, TM Ou, JQ Hou, YJ Lu, SL Huang, HB Luo, JY Wu, ZS Huang, ... Journal of medicinal chemistry 52 (9), 2825-2835, 2009 | 107 | 2009 |
| Synthesis and evaluation of 9-O-substituted berberine derivatives containing aza-aromatic terminal group as highly selective telomeric G-quadruplex stabilizing ligands Y Ma, TM Ou, JH Tan, JQ Hou, SL Huang, LQ Gu, ZS Huang Bioorganic & Medicinal Chemistry Letters 19 (13), 3414-3417, 2009 | 89 | 2009 |
| Stabilization of G-quadruplex DNA by C-5-methyl-cytosine in bcl-2 promoter: implications for epigenetic regulation J Lin, J Hou, H Xiang, Y Yan, Y Gu, J Tan, D Li, L Gu, T Ou, Z Huang Biochemical and biophysical research communications 433 (4), 368-373, 2013 | 81 | 2013 |
| Synthesis and evaluation of novel rutaecarpine derivatives and related alkaloids derivatives as selective acetylcholinesterase inhibitors B Wang, YC Mai, Y Li, JQ Hou, SL Huang, TM Ou, JH Tan, LK An, D Li, ... European journal of medicinal chemistry 45 (4), 1415-1423, 2010 | 71 | 2010 |
| Molecular engineering of thiazole orange dye: Change of fluorescent signaling from universal to specific upon binding with nucleic acids in bioassay YJ Lu, Q Deng, JQ Hou, DP Hu, ZY Wang, K Zhang, LG Luyt, WL Wong, ... ACS Chemical Biology 11 (4), 1019-1029, 2016 | 70 | 2016 |
| Quinolino-benzo-[5, 6]-dihydroisoquindolium compounds derived from berberine: a new class of highly selective ligands for G-quadruplex DNA in c-myc oncogene Y Ma, TM Ou, JH Tan, JQ Hou, SL Huang, LQ Gu, ZS Huang European journal of medicinal chemistry 46 (5), 1906-1913, 2011 | 65 | 2011 |
| Design, synthesis and evaluation of isaindigotone derivatives as dual inhibitors for acetylcholinesterase and amyloid beta aggregation JW Yan, YP Li, WJ Ye, SB Chen, JQ Hou, JH Tan, TM Ou, D Li, LQ Gu, ... Bioorganic & medicinal chemistry 20 (8), 2527-2534, 2012 | 59 | 2012 |
| Design, synthesis and evaluation of isaindigotone derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors L Pan, JH Tan, JQ Hou, SL Huang, LQ Gu, ZS Huang Bioorganic & medicinal chemistry letters 18 (13), 3790-3793, 2008 | 55 | 2008 |
| Synthesis and Evaluation of Quinazolone Derivatives as a New Class of c-KIT G-Quadruplex Binding Ligands X Wang, CX Zhou, JW Yan, JQ Hou, SB Chen, TM Ou, LQ Gu, ZS Huang, ... ACS medicinal chemistry letters 4 (10), 909-914, 2013 | 52 | 2013 |
| Development of a universal colorimetric indicator for G-quadruplex structures by the fusion of thiazole orange and isaindigotone skeleton JW Yan, WJ Ye, SB Chen, WB Wu, JQ Hou, TM Ou, JH Tan, D Li, LQ Gu, ... Analytical chemistry 84 (15), 6288-6292, 2012 | 52 | 2012 |
| New insights into the structures of ligand− quadruplex complexes from molecular dynamics simulations JQ Hou, SB Chen, JH Tan, TM Ou, HB Luo, D Li, J Xu, LQ Gu, ZS Huang The Journal of Physical Chemistry B 114 (46), 15301-15310, 2010 | 47 | 2010 |
| 3D-QSAR studies of azaoxoisoaporphine, oxoaporphine, and oxoisoaporphine derivatives as anti-AChE and anti-AD agents by the CoMFA method YP Li, X Weng, FX Ning, JB Ou, JQ Hou, HB Luo, D Li, ZS Huang, ... Journal of Molecular Graphics and Modelling 41, 61-67, 2013 | 38 | 2013 |
| Chemical intervention of the NM23-H2 transcriptional programme on c-MYC via a novel small molecule C Shan, J Lin, JQ Hou, HY Liu, SB Chen, AC Chen, TM Ou, JH Tan, D Li, ... Nucleic acids research 43 (14), 6677-6691, 2015 | 37 | 2015 |
| 2-(2-indolyl-)-4(3H)-quinazolines derivates as new inhibitors of AChE: design, synthesis, biological evaluation and molecular modelling Z Li, B Wang, JQ Hou, SL Huang, TM Ou, JH Tan, LK An, D Li, LQ Gu, ... Journal of enzyme inhibition and medicinal chemistry 28 (3), 583-592, 2013 | 35 | 2013 |
| Impact of planarity of unfused aromatic molecules on G-quadruplex binding: Learning from isaindigotone derivatives JQ Hou, JH Tan, XX Wang, SB Chen, SY Huang, JW Yan, SH Chen, ... Organic & biomolecular chemistry 9 (18), 6422-6436, 2011 | 35 | 2011 |
| An integrated approach for discovery of highly potent and selective Mnk inhibitors: Screening, synthesis and SAR analysis T Teo, Y Yang, M Yu, SKC Basnet, T Gillam, J Hou, RM Schmid, ... European journal of medicinal chemistry 103, 539-550, 2015 | 34 | 2015 |
