Wild-type p53 triggers a rapid senescence program in human tumor cells lacking functional p53 MM Sugrue, DY Shin, SW Lee, SA Aaronson Proceedings of the National Academy of Sciences 94 (18), 9648-9653, 1997 | 360 | 1997 |
p38 kinase regulates nitric oxide-induced apoptosis of articular chondrocytes by accumulating p53 via NFκB-dependent transcription and stabilization by serine 15 phosphorylation SJ Kim, SG Hwang, DY Shin, SS Kang, JS Chun Journal of Biological Chemistry 277 (36), 33501-33508, 2002 | 228 | 2002 |
p53 negatively regulates cdc2 transcription via the CCAAT-binding NF-Y transcription factor J Yun, HD Chae, HE Choy, J Chung, HS Yoo, MH Han, DY Shin Journal of Biological Chemistry 274 (42), 29677-29682, 1999 | 205 | 1999 |
Roscovitine sensitizes glioma cells to TRAIL-mediated apoptosis by downregulation of survivin and XIAP EH Kim, SU Kim, DY Shin, KS Choi Oncogene 23 (2), 446-456, 2004 | 181 | 2004 |
The absence of ribonuclease H1 or H2 alters the sensitivity of Saccharomyces cerevisiae to hydroxyurea, caffeine and ethyl methanesulphonate: implications for roles of RNases H … A Arudchandran, S Cerritelli, S Narimatsu, M Itaya, DY Shin, Y Shimada, ... Genes to cells 5 (10), 789-802, 2000 | 169 | 2000 |
Heat Shock Response of Saccharomyces cerevisiae Mutants Altered in Cyclic AMP-Dependent Protein Phosphorylation DY Shin, K Matsumoto, H Iida, I Uno, T Ishikawa Molecular and cellular biology 7 (1), 244-250, 1987 | 165 | 1987 |
Constitutive activation of cyclin B1-associated cdc2 kinase overrides p53-mediated G2-M arrest M Park, HD Chae, J Yun, M Jung, YS Kim, SH Kim, MH Han, DY Shin Cancer Research 60 (3), 542-545, 2000 | 144 | 2000 |
Characterization of a Protein Kinase C-δ (PKC-δ) ATP Binding Mutant: AN INACTIVE ENZYME THAT COMPETITIVELY INHIBITS WILD TYPE PKC-δ ENZYMATIC ACTIVITY (∗) W Li, JC Yu, DY Shin, JH Pierce Journal of Biological Chemistry 270 (14), 8311-8318, 1995 | 118 | 1995 |
p53 and its homologues, p63 and p73, induce a replicative senescence through inactivation of NF-Y transcription factor MS Jung, J Yun, HD Chae, JM Kim, SC Kim, TS Choi, DY Shin Oncogene 20 (41), 5818-5825, 2001 | 114 | 2001 |
Cdk2-dependent phosphorylation of the NF-Y transcription factor and its involvement in the p53-p21 signaling pathway J Yun, HD Chae, TS Choi, EH Kim, YJ Bang, J Chung, KS Choi, ... Journal of Biological Chemistry 278 (38), 36966-36972, 2003 | 106 | 2003 |
Cdk2-dependent phosphorylation of the NF-Y transcription factor is essential for the expression of the cell cycle-regulatory genes and cell cycle G1/S and G2/M transitions HD Chae, J Yun, YJ Bang, DY Shin Oncogene 23 (23), 4084-4088, 2004 | 91 | 2004 |
Oocyte-based screening of cytokinesis inhibitors and identification of pectenotoxin-2 that induces Bim/Bax-mediated apoptosis in p53-deficient tumors HD Chae, TS Choi, BM Kim, JH Jung, YJ Bang, DY Shin Oncogene 24 (30), 4813-4819, 2005 | 82 | 2005 |
DNA damage induces the IL-6/STAT3 signaling pathway, which has anti-senescence and growth-promoting functions in human tumors UJ Yun, SE Park, YS Jo, J Kim, DY Shin Cancer letters 323 (2), 155-160, 2012 | 78 | 2012 |
Factor analysis of the metabolic syndrome among elderly Koreans—the South‐west Seoul Study KM Choi, J Lee, KB Kim, DR Kim, SK Kim, DH Shin, NH Kim, IB Park, ... Diabetic medicine 20 (2), 99-104, 2003 | 70 | 2003 |
Bcl-xL and E1B-19K proteins inhibit p53-induced irreversible growth arrest and senescence by preventing reactive oxygen species-dependent p38 activation MS Jung, DH Jin, HD Chae, S Kang, SC Kim, YJ Bang, TS Choi, K Choi, ... Journal of Biological Chemistry 279 (17), 17765-17771, 2004 | 65 | 2004 |
A randomized phase I comparative pharmacokinetic study comparing SB 5 with reference adalimumab in healthy volunteers D Shin, Y Lee, H Kim, T Körnicke, R Fuhr Journal of Clinical Pharmacy and Therapeutics 42 (6), 672-678, 2017 | 62 | 2017 |
A novel human ERK phosphatase regulates H-ras and v-raf signal transduction DY Shin, T Ishibashi, TS Choi, E Chung, IY Chung, SA Aaronson, ... Oncogene 14 (22), 2633-2639, 1997 | 61 | 1997 |
Identification of a novel anti-apoptotic E3 ubiquitin ligase that ubiquitinates antagonists of inhibitor of apoptosis proteins SMAC, HtrA2, and ARTS J Kim, SY Kim, BM Kim, H Lee, I Kim, J Yun, Y Jo, T Oh, Y Jo, HD Chae, ... Journal of Biological Chemistry 288 (17), 12014-12021, 2013 | 53 | 2013 |
Suppression of distant pulmonary metastasis of MDA‐MB 435 human breast carcinoma established in mammary fat pads of nude mice by retroviral‐mediated TIMP‐2 gene transfer YK Lee, IS So, SC Lee, JH Lee, CW Lee, WM Kim, MK Park, ST Lee, ... The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2005 | 38 | 2005 |
Inactivation of p38 kinase delays the onset of senescence in rabbit articuilar chondrocytes S Kang, M Jung, CW Kim, DY Shin Mechanisms of ageing and development 126 (5), 591-597, 2005 | 29 | 2005 |