Primary structure, synthesis, and biological activity of rat endothelin, an endothelium-derived vasoconstrictor peptide. M Yanagisawa, A Inoue, T Ishikawa, Y Kasuya, S Kimura, S Kumagaye, ... Proceedings of the National Academy of Sciences 85 (18), 6964-6967, 1988 | 729 | 1988 |
Positive inotropic action of novel vasoconstrictor peptide endothelin on guinea pig atria T Ishikawa, M Yanagisawa, S Kimura, K Goto, T Masaki American Journal of Physiology-Heart and Circulatory Physiology 255 (4 …, 1988 | 579 | 1988 |
Endothelin activates the dihydropyridine-sensitive, voltage-dependent Ca2+ channel in vascular smooth muscle. K Goto, Y Kasuya, N Matsuki, Y Takuwa, H Kurihara, T Ishikawa, S Kimura, ... Proceedings of the National Academy of Sciences 86 (10), 3915-3918, 1989 | 483 | 1989 |
Positive chronotropic effects of endothelin, a novel endothelium-derived vasoconstrictor peptide T Ishikawa, M Yanagisawa, S Kimura, K Goto, T Masaki Pflügers Archiv 413, 108-110, 1988 | 283 | 1988 |
Regulation of Ca2+ channels by cAMP and cGMP in vascular smooth muscle cells. T Ishikawa, JR Hume, KD Keef Circulation research 73 (6), 1128-1137, 1993 | 191 | 1993 |
Involvement of endothelin in the regulation of human vascular tonus. Potent vasoconstrictor effect and existence in endothelial cells. T Miyauchi, Y Tomobe, R Shiba, T Ishikawa, M Yanagisawa, S Kimura, ... Circulation 81 (6), 1874-1880, 1990 | 177 | 1990 |
Characteristics of pressor response to endothelin in spontaneously hypertensive and Wistar-Kyoto rats. T Miyauchi, T Ishikawa, Y Tomobe, M Yanagisawa, S Kimura, Y Sugishita, ... Hypertension 14 (4), 427-434, 1989 | 137 | 1989 |
Mechanism of contraction to endothelin in isolated porcine coronary artery Y Kasuya, T Ishikawa, M Yanagisawa, S Kimura, K Goto, T Masaki American Journal of Physiology-Heart and Circulatory Physiology 257 (6 …, 1989 | 103 | 1989 |
Modulation of K+ and Ca2+ channels by histamine H1‐receptor stimulation in rabbit coronary artery cells. T Ishikawa, JR Hume, KD Keef The Journal of Physiology 468 (1), 379-400, 1993 | 81 | 1993 |
Positive inotropic effect of calcitonin gene-related peptide mediated by cyclic AMP in guinea pig heart. T Ishikawa, N Okamura, A Saito, T Masaki, K Goto Circulation research 63 (4), 726-734, 1988 | 77 | 1988 |
Vasodilating effects of human and rat calcitonin gene-related peptides in isolated porcine coronary arteries T Shoji, I Ishihara, T Ishikawa, A Saito, K Goto Naunyn-Schmiedeberg's archives of pharmacology 336, 438-444, 1987 | 76 | 1987 |
Interactive role of tyrosine kinase, protein kinase C, and Rho/Rho kinase systems in the mechanotransduction of vascular smooth muscles K Nakayama, K Obara, Y Tanabe, M Saito, T Ishikawa, S Nishizawa Biorheology 40 (1-3), 307-314, 2003 | 73 | 2003 |
Role of calcitonin gene-related peptide as cardiotonic neurotransmitter in guinea pig left atria. A Saito, T Ishikawa, S Kimura, K Goto Journal of Pharmacology and Experimental Therapeutics 243 (2), 731-736, 1987 | 71 | 1987 |
Intracellular divalent cations block smooth muscle K+ channels. CH Gelband, T Ishikawa, JM Post, KD Keef, JR Hume Circulation research 73 (1), 24-34, 1993 | 67 | 1993 |
Dual effect of nitric oxide on cytosolic Ca2+concentration and insulin secretion in rat pancreatic β-cells Y Kaneko, T Ishikawa, S Amano, K Nakayama American Journal of Physiology-Cell Physiology 284 (5), C1215-C1222, 2003 | 66 | 2003 |
Interactive role of protein kinase C-δ with rho-kinase in the development of cerebral vasospasm in a canine two-hemorrhage model K Obara, S Nishizawa, M Koide, K Nozawa, A Mitate, T Ishikawa, ... Journal of vascular research 42 (1), 67-76, 2005 | 61 | 2005 |
Characteristics of binding of endothelin-1 and endothelin-3 to rat hearts. Developmental changes in mechanical responses and receptor subtypes. T Ishikawa, LM Li, O Shinmi, S Kimura, M Yanagisawa, K Goto, T Masaki Circulation research 69 (4), 918-926, 1991 | 59 | 1991 |
Mechanisms of altered sensitivity to endothelin-1 between aortic smooth muscles of spontaneously hypertensive and Wistar-Kyoto rats. Y Tomobe, T Ishikawa, M Yanagisawa, S Kimura, T Masaki, K Goto Journal of Pharmacology and Experimental Therapeutics 257 (2), 555-561, 1991 | 58 | 1991 |
Characterization of endothelium-dependent relaxation independent of NO and prostaglandins in guinea pig coronary artery A Yamanaka, T Ishikawa, K Goto Journal of Pharmacology and Experimental Therapeutics 285 (2), 480-489, 1998 | 54 | 1998 |
Role of α2C‐adrenoceptors in the reduction of skin blood flow induced by local cooling in mice M Honda, M Suzuki, K Nakayama, T Ishikawa British journal of pharmacology 152 (1), 91-100, 2007 | 53 | 2007 |